Clinical trials: Post-operative Cardiac Surgery
Injection, Non-cardiac Surgery
A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery
To observe and study the clinical effect of Huperzine A Injection on reducing postoperative delirium in elderly patients undergoing non-cardiac surgery
- Conditions
- Injection, Non-cardiac Surgery, Delirium in Old Age, Post Operative Delirium
- Trial name
- NCT05242419
- Testing
- Sodium Chloride Injection, Huperzine A Injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Postoperative Pulmonary Complications (PPCs), Cardiac Surgery in Adult Patient
Sigh Ventilation in Cardiac Surgery
The purpose of this trial is to investigate whether sigh ventilation strategy, combining sigh breaths, low tidal volume, and moderate PEEP levels, protects against major pulmonary complications within the first 7 postoperative…
- Trial name
- NCT07024420
- Testing
- Sigh Breaths, Low Tidal Volume, Moderate PEEP
- Where
- China
- Volunteers
- 686 people
- Sponsor
- Zhongda Hospital
Cardiac Valve Disease
Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries
Comparison between the effects of intrathecal morphine versus intrathecal dexmedetomidine on analgesia and respiratory function, in open heart surgery.
- Trial name
- NCT06076759
- Testing
- Intrathecal morphine or dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pain, Postoperative, Opioid Use
Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain
The goal of this pilot study is to describe and compare Ultrasound-Guided Erector Spinae Plane (ESP) Blocks using Exparel® (bupivacaine liposome injectable suspension) to Marcaine® (bupivacaine hydrochloride) for pain management…
- Conditions
- Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
- Trial name
- NCT06077422
- Testing
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Rutgers, The State University of New Jersey
Heart Diseases, Atrial Fibrillation
Clinical Value of Remote Ischemic Preconditioning
Objectives: Despite utilization of available means for cardioprotection during cardiac surgery, myocardial injury still occurs. Further improvement of cardioprotection is therefore necessary.
- Trial name
- NCT01740102
- Testing
- RIPC
- Where
- Norway
- Volunteers
- 92 people
- Sponsor
- Norwegian University of Science and Technology
Infective Endocarditis, Infection Related to Ventricular Assist Device
Retrospective Analysis of Nephrotoxicity During Daptomycin Versus Vancomycin Treatments in High Risk Patients
Acute kidney injury (AKI) is a frequent complication that occurs in 15 to 25% of patients after vascular surgery, and up to 40% of patients after cardiac surgery.
- Conditions
- Infective Endocarditis, Infection Related to Ventricular Assist Device, Infection Related to Vascular Prothesis, Surgical Site Infection
- Trial name
- DVN (NCT03961503)
- Testing
- Daptomycin (DAP) treatment, Vancomycin (VAN) treatment
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Post-cardiac Surgery
Dexmedetomidine Enhancing the Recovery After Cardiac Surgery
Enhanced Recovery After Surgery (ERAS) aims to facilitate a quicker and smoother recovery period following surgical procedures. The implementation of these protocols may lead to patients returning to their daily activities…
- Trial name
- NCT06907277
- Testing
- Dexmedetomidine, Fentanyl, Lidocain
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Anxiety and Fear, Anxiety Depression
Psychological Well-being of Patients Awaiting for Cardiac Surgery During the COVID-19 Pandemic
The effect and impact of postponing cardiac surgery / creating a waiting list as a result of COVID-19 on patients, both psychologically and symptomatically on three groups of patients: 1.
- Conditions
- Anxiety and Fear, Anxiety Depression, Anxiety Postoperative, Psychological Stress
- Trial name
- NCT04406181
- Testing
- HADS, a survey
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pericardial Effusion
Cochicine Treatment for Post- Operative Pericardial Effusion
Background: The incidence of asymptomatic pericardial effusion is high after cardiac surgery. Objective: To assess whether colchicine is effective in reducing post operative pericardial effusion volume.
- Trial name
- POPE2 (NCT01266694)
- Testing
- Colchicines
- Where
- 10 sites in France
- Volunteers
- 199 people
- Sponsor
- French Cardiology Society
Cardiac Output, Surgery
Personalized Hemodynamic Management in High-risk Major Abdominal Surgery
Postoperative mortality within 30 days after surgery is around 2% in patients having major noncardiac surgery in Europe and the USA.
- Conditions
- Cardiac Output, Surgery, Postoperative Complications, Anesthesia
- Trial name
- PELICAN (NCT05648279)
- Testing
- Personalized hemodynamic management
- Where
- 12 sites in Austria, Czechia and 3 more
- Volunteers
- 1,128 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Pain
Ropivacaine After Sternotomy
Continuous ropivacaine infusion to sternotomy wound after coronary artery bypass grafting (CABG) or heart valve surgery to diminish postoperative pain.
- Trial name
- NAROSYD (NCT02449486)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Kuopio University Hospital
Heart; Dysfunction Postoperative, Cardiac Surgery, Adverse Anesthesia Outcome
The Prognostic Value of Troponin T for Long-term Outcome After Cardiac Surgery
This survey has two aims. First, we would like to be informed about the health condition of our patients two years following heart surgery at University Hospital, Basel.
- Trial name
- NCT00468598
- Where
- Switzerland
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Complication of Anesthesia, Ischaemia-reperfusion Injury
Dexmedetomidine Effect on Mitochondrial Function
The investigators hypothesize that in addition to a known sympatholytic effect, intraoperative dexmedetomidine reduces adverse changes in mitochondrial function and structure attenuating ischaemia-reperfusion and end-organ injury…
- Trial name
- NCT02299063
- Testing
- Dexmedetomidine, 0.9% NaCl
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Hospital for Sick Children
Acute Renal Failure
A New Way to Detect Acute Kidney Injury
Acute renal failure after cardiac surgery is a common postoperative complication, affecting approximately 20% of patients. It is associated with an increase in short-term mortality and an increase in hospital stay; but is also…
- Trial name
- VEX-CARDS (NCT07198906)
- Testing
- Determination of VEXUS score and onset of chronic renal failure
- Where
- France
- Sponsor
- University Hospital, Rouen
Post-Op Complication
Perioperative Smart Device Monitoring to Predict Complications
This is a prospective, single-center, observational study designed to to quantify complications following non cardiac intermediate and high-risk surgery, and to identify digital biomarkers (collected pre, and post-operatively by…
- Trial name
- PreSmart (NCT06156033)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Atrial Fibrillation, Atrial Flutter
Pericardiotomy in Cardiac Surgery
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Cardiac Events
- Trial name
- PRINCE (NCT06486636)
- Testing
- Left Posterior Pericardiotomy
- Where
- 19 sites in United States, Austria and 3 more
- Volunteers
- 1,400 people
- Sponsor
- Population Health Research Institute
Cardiopulmonary Bypass, Cardiac Surgery
Ulinastatin Improves Postoperative Oxygenation After Cardiopulmonary Bypass
Retrospective study determine whether ulinastatin enhances postoperative pulmonary oxygenation after cardiopulmonary bypass (CPB).
- Trial name
- NCT03154814
- Testing
- ulinastatin, control
- Where
- 2 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Konkuk University Medical Center
Acute Kidney Injury
Application of Intraoperative Transesophageal Echocardiography Imaging of Vein and CLCVP in Early Prediction and Intervention CSA-AKI
The goal of this clinical trial is to learn about in postoperative acute kidney injury in cardiac surgery. The main questions it aims to answer are: Intraoperative Transesophageal Ultrasound Doppler venous imaging can be used to…
- Trial name
- NCT05682716
- Testing
- Controlled low central venous pressure (CLCVP) technology, Nitroglycerin
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
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