Clinical trials: Post-operative Cardiac Surgery
Complex Congenital Heart Disease, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in the Correction of Complex Congenital Heart Disease
This study is a multicenter, stepwise design, cluster randomized controlled trial. Random sequence is generated by computer, and each center enters the intervention expectation (Phase I) in random order to implement ERAS…
- Trial name
- NCT05914103
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,030 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Cardiac Surgery, Postoperative Pain
Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block for Cardiac Surgery
This prospective, randomized, controlled study aims to evaluate the effects of ultrasound-guided bilateral single-shot serratus posterior superior intercostal plane (SPSIP) block on postoperative recovery and pain management in…
- Conditions
- Cardiac Surgery, Postoperative Pain, Postoperative Recovery After Cardiac Surgery
- Trial name
- NCT07785323
- Testing
- Serratus posterior superior intercostal plane block, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Burak Çilingir
Depression, Anxiety
Postoperative Anxiety and Depression Among Older Chinese Patients
A multicenter, prospective observational study to describe the socioeconomic characteristics and the occurrence of postoperative anxiety and depression in the Chinese old population.
- Conditions
- Depression, Anxiety, Elderly Patients, Non-cardiac Surgery
- Trial name
- NCT06495840
- Testing
- no intervention
- Where
- China
- Sponsor
- Chinese PLA General Hospital
CABG, Cardiac Anesthesia
Impact of the Cardiopulmonary Bypass and Cross-Clamp Time Ratio on Postoperative Outcomes in Open Heart Surgery: A Prospective Observational Analysis
This study aims to investigate the relationship between the ratio of cardiopulmonary bypass (CPB) time to cross-clamp (CC) time and postoperative complications in open heart surgery.
- Conditions
- CABG, Cardiac Anesthesia, Cardiac Surgery Prognosis, Bypass Complication
- Trial name
- NCT06873620
- Where
- Turkey (Türkiye)
- Volunteers
- 348 people
- Sponsor
- Ahmet Yuksek
Graft Patency, Coronary Artery Bypass Grafting Surgery
ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery
The purpose of this study is to determine whether adding clopidogrel to aspirin after coronary bypass operation (CABG) improves graft patency, in patients that have preoperatively increased platelet activity(hypercoagulable) and…
- Conditions
- Graft Patency, Coronary Artery Bypass Grafting Surgery, Hypercoagulability, Thrombosis
- Trial name
- TEG-CABG (NCT01046942)
- Testing
- Clopidogrel+acetylsalicylic acid, acetylsalicylic acid
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative, Anesthesia, Local
Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
This study aims to investigate the effect of transversus thoracis muscle plane block (TTP), using repeated boluses of ropivacaine via catheter, on postoperative pain and oxycodone consumption after elective cardiac surgery with…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- TTPcat (NCT04916418)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Postoperative Mortality, Anesthesia
The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China
At present, the elderly population in China has reached 241 million, and there are more than 20 million elderly surgical patients every year, accounting for about 25% of the surgical population.
- Conditions
- Postoperative Mortality, Anesthesia, Elderly Patients, Noncardiac Surgery
- Trial name
- NCT04389008
- Testing
- no interventions
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Chinese PLA General Hospital
Analgesia
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block
In 2012 Blanco et al. [1] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries.
- Trial name
- NCT06636578
- Testing
- dexmedetomidine, ropivacaine, fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Cardiorespiratory; Insufficiency, Due to A Procedure, Long-Term, Cardiac Surgery
Changes in Fitness and Strength in Postoperative Cardiac Patients Undergoing Exercise Therapy: Biological and Functional Mechanisms of Recovery
This study seeks to determine the biological, physiological and psychological effects of supervised exercise programs in patients surviving open heart surgery.
- Trial name
- NCT04903691
- Testing
- Cardiac Exercise Program
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Yale University
Atrial Fibrillation
READ-POAF Pilot Studies Postoperative Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation after coronary artery bypass grafting will be monitored up to 1 year after the procedure by implanting a Reveal XT internal loop recorder two weeks before the surgery.
- Trial name
- NCT01530750
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Open Heart Surgery, Postoperative Pain
Postoperative Pain Alleviation in Open Heart Surgery
Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation.
- Trial name
- NCT03106818
- Testing
- bupivacain with magnesium sulphate, Bupivacaine only, conventional
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Surgery, Cardiac, Atrial Fibrillation
Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Postoperative atrial fibrillation is quite common after cardiac surgery with up to 1 in 3 patients experiencing this abnormal heart rhythm.
- Trial name
- PATRONUS (NCT05543278)
- Testing
- Amiodarone
- Volunteers
- 242 people
- Sponsor
- Massachusetts General Hospital
Atrial Fibrillation, Surgery--Complications
Incidence of Post-operative Atrial Fibrillation Secondary to Abdominal Surgery
Background and purpose Post-operative AF (POAF) is considered a phenomenon rather than a definite diagnosis and the current clinical guidelines have no specific recommendations regarding its management.
- Trial name
- SECAFIB-SURG (NCT04090905)
- Testing
- Standard clinical monitoring, Holter monitoring
- Where
- Denmark
- Volunteers
- 466 people
- Sponsor
- Frederiksberg University Hospital
Cardiac Surgery, Coronary Artery Bypass Grafting
Oscillating Positive Expiratory Pressure (OPEP) Therapy in High Risk Patients Following Cardiac Surgery
Respiratory dysfunction following cardiac surgery is well documented and due in part to the location of the incision and nature of the surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Chronic Obstructive Pulmonary Disease (COPD), Older Adults
- Trial name
- NCT02732574
- Testing
- Oscilatory Positive Expiratory Pressure (OPEP) device
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post-Operative Atrial Fibrillation, Acupuncture Therapy
Acupuncture Treatment for Patients Who Develop Arrhythmias in the Post-Operative Cardio-Thoracic Setting
A feasibility study on the provision of acupuncture treatment in the hospital to 20 patients who have undergone open heart surgery procedures. The acupuncture treatments may begin as early as postoperative Day 2.
- Trial name
- NCT03525860
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Mayo Clinic
Perioperative Myocardial Injury, Myocardial Injury After Non-Cardiac Surgery
Intrahepatic Blood Flow Occlusion and Cardiac Injury Risk in Partial Hepatectomy
The goal of this observational study is to examine whether intrahepatic blood flow occlusion strategies during partial hepatectomy are associated with postoperative cardiac injury in patients undergoing hepatectomy.
- Conditions
- Perioperative Myocardial Injury, Myocardial Injury After Non-Cardiac Surgery, Hypotension, Ischemia Reperfusion Injury
- Trial name
- NCT06753461
- Testing
- intrahepatic blood flow occlusion
- Volunteers
- 2,600 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
PERCUTANEOUS CORONARY INTERVENTION, STENTS
The Surgery After Stenting (SAS) Registry
The SAS registry will include any patient with previous coronary stenting undergoing any type of surgery or operative endoscopic/endovascular procedure at the participating Centers.
- Conditions
- PERCUTANEOUS CORONARY INTERVENTION, STENTS, SURGERY
- Trial name
- SAS registry (NCT01997242)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Postoperative; Dysfunction Following Cardiac Surgery
Cerebral Energy State in Cardiac Surgery
Impaired cerebral function remains an important complication of cardiopulmonary bypass (CPB) during cardiac surgery. The aim of the present study is to investigate whether the lactate to pyruvate (LP) ratio obtained by…
- Trial name
- NCT02846818
- Testing
- Microdialysis
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Postoperative Delirium
Risk Factors for Postoperative Delirium in Elderly Patients Undergoing Major Non-Cardiac Surgery in Singapore
The primary aim is to establish the risk factors, in particular the modifiable risk factors, for the development of POD in elderly patients undergoing major non-cardiac surgery in a tertiary hospital in Singapore.
- Trial name
- NCT04617210
- Testing
- Neurocognitive tests and blood taking
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University Hospital, Singapore
Anemia, Intensive Care
Observational Study of Iron Metabolism in Anemia in ICU and Post-Operative Patients
Anemia in intensive care and post-operative patients is due to both blood loss (leading to iron loss) and inflammation.
- Conditions
- Anemia, Intensive Care, Cardiac Surgery
- Trial name
- FAIRe (NCT00338234)
- Where
- France
- Volunteers
- 153 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.