Clinical trials: Post-operative Cardiac Surgery
Anemia, Coronary Artery Bypass Surgery
Randomized Trial of a Liberal Versus a Restrictive Transfusion Strategy in Elderly Cardiac Surgery Patients
The purpose of this study is to determine whether a less restrictive strategy of red blood cell transfusion in elderly patients following coronary bypass surgery results in enhanced postoperative recovery as determined by quality…
- Trial name
- NCT00318227
- Testing
- Blood Transfusion
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ischemia Reperfusion Injury
Remote Ischemic Preconditioning in Cardiac Surgery
Aim of the work : Evaluation of the role of Remote Ischemic Preconditioning (RIP) on liver function in patients undergoing on-pump cardiac surgery.
- Trial name
- NCT04647370
- Testing
- remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Coronary Artery Disease
Antegrade Autologous Blood Reinfusion After CPB
This prospective observational study aims to evaluate the effect of antegrade pump blood reinfusion using the crystalloid "chase" technique on postoperative transfusion requirements in adult patients undergoing cardiac surgery…
- Trial name
- NCT07420582
- Testing
- Antegrade Pump Blood Reinfusion, No Anterograde Pump Blood Reinfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Kocaeli City Hospital
Auricular Acupressure, Cervical Spine Surgery
Auricular Acupressure on Improving Pain and Heart Variability in Patients After Cervical Spine Surgery
The primary objective of this study is to investigate the effectiveness of auricular acupressure in improving post-cervical spine surgery pain and heart rate variability in patients.
- Trial name
- NCT06087380
- Testing
- auricular acupressure, standard ward care
- Where
- Taiwan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Pain, Postoperative, Atrial Fibrillation
BRS and Outcomes in Cardiothoracic Surgery
The purpose of this study is to determine whether baroreceptor sensitivity (the ability of your body to change your heart rate and/or blood pressure in response to a situation) has any effect on how likely you are to suffer…
- Conditions
- Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
- Trial name
- NCT03243279
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Atrial Fibrillation New Onset, Hemorrhage
Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation
The aim of this study is to evaluate the prophylactic effects of Ranolazine on new onset atrial fibrillation in post-operative coronary artery bypass graft and valve surgery patient population at Staten Island University hospital.
- Conditions
- Atrial Fibrillation New Onset, Hemorrhage, Prolonged QTc Interval, Ventricular Tachycardia
- Trial name
- NCT01590979
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Postoperative Delirium
Effect of Cerebral Oxygen Saturation Intervention
Postoperative delirium (POD) is a common complication after cardiac surgery,and the pathogenesis is considered imbalance of cerebral oxygen.
- Trial name
- ECOS (NCT04212988)
- Testing
- Increase the SCO2 value
- Where
- China
- Volunteers
- 140 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Coronary Artery Disease
Perioperative Depression and Postoperative Arrhythmia in Elective Coronary Bypass Graft Surgery
Postoperative arrhythmias (heart irregularities) are one of the most common complications after cardiac surgery and are associated with increased morbidity and mortality.
- Trial name
- NCT00622024
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Congenital Heart Disease
Relationship of Brain Natriuretic Peptide (BNP) Levels to Cardiac Diagnosis, Operation Performed, Post-operative Course and Outcome
The purpose of this study is to assess brain natriuretic peptide levels to evaluate the relationship of those levels with the diagnosis of congenital cardiac disease, operation performed, post-operative course, and outcome.
- Trial name
- NCT00238810
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Healthcare of Atlanta
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Colorectal Cancer, Intraoperative Hemodynamic Management
MAP- Versus Cardiac Index-Guided Hemodynamic Management in Colorectal Surgery
This prospective randomized trial aims to compare the effects of two intraoperative hemodynamic management strategies on early postoperative renal function in patients undergoing colorectal surgery.
- Trial name
- NCT07609680
- Testing
- Mean Arterial Pressure-Guided Hemodynamic Management, Cardiac Index-Guided Hemodynamic Management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pain, Cardiac Surgery
Comparison of Paravertebral Block and Deep Parasternal Intercostal Plane Block in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is often associated with significant postoperative pain. Poor pain control after sternotomy may increase opioid use, delay mobilization, prolong extubation time, and…
- Conditions
- Postoperative Pain, Cardiac Surgery, Postoperative Pain After Cardiac Surgery Via Median Sternotomy
- Trial name
- SPARE-CABG (NCT07498946)
- Testing
- Thoracic paravertebral block (TPVB), Bilateral Deep Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Surgery, Non Cardiac Surgery
Surgical Start Time and Prognosis
Surgical start times significantly impacted mortality, morbidity, and resource utilization, particularly in high-risk patients.
- Trial name
- NCT06792578
- Testing
- Surgical Start Time
- Where
- South Korea
- Volunteers
- 291,051 people
- Sponsor
- Asan Medical Center
Intracranial Hypertension
Effects of Extracorporeal Circulation Techniques on Cerebral Perfusion in CABG Surgery
This prospective study aims to compare the effects of minimal invasive extracorporeal circulation (MiECC) and conventional reservoir-based extracorporeal circulation techniques on cerebral perfusion in patients undergoing…
- Trial name
- NCT07420738
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kartal Kosuyolu High Speciality Training and Research Hospital
Organ Protection
Effect of Intravenous Lidocaine on Serum miRNA-135a in Patients Undergoing Non-cardiac Surgery
The purpose of this study is to investigate the effects of intravenous lidocaine on serum miRNA-135a and its downstream proteins Rock2 and Add1 in elderly patients undergoing non-cardiac under general anesthesia.
- Trial name
- NCT05503043
- Testing
- Lidocaine, Normal saline
- Volunteers
- 50 people
- Sponsor
- General Hospital of Ningxia Medical University
Open Heart Surgery, Cardiopulmonary Bypass
Procalcitonin and Postoperative Outcome After Open-heart Surgery
The aim of this study was to investigate the impact of serum values of procalcitonin (PCT), C-reactive protein (CRP) and lactate to predict postoperative complications in the early postoperative period after open-heart surgery…
- Conditions
- Open Heart Surgery, Cardiopulmonary Bypass, Procalcitonin, C-reactive Protein
- Trial name
- NCT04213040
- Testing
- Serum levels of Procalcitonin, C-reactive protein, lactate
- Volunteers
- 214 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Surgical Site Infection
24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis
A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd generation cephalosporin…
- Trial name
- NCT04303390
- Testing
- Cefuroxime, Cefazolin, 24 hours
- Where
- Saudi Arabia
- Volunteers
- 568 people
- Sponsor
- Saud Al Babtain Cardiac Center
Eye Abnormalities, Arrythmia
Relation Between Oculocardiac Reflex and Laryngospasm
The aim of this study is to evaluate whether there is a significant relation between various arrhythmias during the surgeon's stretching the eye muscles and laryngospasm and emergence agitation in strabismus surgeries
- Trial name
- NCT05339880
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Cardiac Disease Minimally Invasive Cardiac Surgery Postoperative Pain
Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based Anesthesia
Enhanced Recovery After Surgery (ERAS) protocols have revolutionized perioperative management by implementing evidence-based, patient-centered strategies that improve clinical outcomes, shorten hospital length of stay, and reduce…
- Trial name
- Esp (NCT07749274)
- Testing
- Dexmedetomidine, Ultrasound-Guided Bilateral Erector Spinae Plane Block (ESPB), Fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Complication, Postoperative, Cardiac Complication
Acute Effect of Positive Expiratory Pressure Versus Breath Stacking Technique After Cardiac Surgery
This study evaluates the efficacy and safety of a single session of positive expiratory pressure and of breath stacking technique in patients after cardiac surgery.
- Trial name
- NCT04013360
- Testing
- Breath Stacking, Expiratory Positive Airway Pressure
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Santa Maria
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