Clinical trials: Post-operative Cardiac Surgery
Atrial Fibrillation New Onset
Cost-effectiveness Analysis Between Two Anticoagulation Strategies for Atrial Fibrillation in the Postoperative Period of Coronary Artery Bypass Graft Surgery
Coronary artery bypass graft (CABG) surgery is a common intervention in patients with coronary artery disease (CAD). The presence of new postoperative atrial fibrillation / atrial flutter (POAF) occurs in 15-40% of patients…
- Trial name
- TASK-POAF (NCT05300555)
- Testing
- Rivaroxaban 20 MG Oral Tablet, Warfarin
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Cognitive Dysfunction, Postoperative Delirium
Ulinastatin Improves Post-Cardiac Surgery Cognitive Dysfunction
The study comprised two primary components: a retrospective analysis of clinical big data and a conventional prospective cohort study involving patients undergoing cardiac surgery. The objectives were: 1.
- Trial name
- NCT06268249
- Testing
- Ulinastatin
- Where
- China
- Volunteers
- 7,065 people
- Sponsor
- Qin Zhang
Postoperative Delirium
Postoperative Delirium in Patients Undergoing Cardiac Surgery
Establish a follow-up database for postoperative delirium in cardiac surgery patients, adopt a bidirectional cohort design to simultaneously analyze the associations between "preoperative exposure factors and postoperative…
- Trial name
- NCT07239648
- Testing
- Serum metabolic profile
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xijing Hospital
Postoperative Atrial Fibrillation
Quality of Life in Patients With Postoperative Atrial Fibrillation After Cardiac Surgery
Prospective observational study on quality of life with postoperative atrial fibrillation after cardiac surgery using SF-36 and qualitative questions
- Trial name
- NCT07173998
- Testing
- Survey
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain, Regional Anaesthsia
Parasternal and Adductor Canal Blocks in CABG
This randomized controlled trial evaluates the effectiveness of different postoperative analgesic strategies in patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Postoperative Pain, Regional Anaesthsia, Pain Management
- Trial name
- NCT07599748
- Testing
- parasternal block, Parasternal block + Adductor canal block, conventional analgesic regimen
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Zonguldak Bulent Ecevit University
Postoperative Complications
Left Ventricular Global Longitudinal Strain and Postoperative Myocardial Injury
To use left ventricular global longitudinal strain as a means of monitoring myocardial exercise function during anaesthesia in patients with coronary artery disease, to explore the association with the occurrence of postoperative…
- Trial name
- NCT05392426
- Testing
- Left Ventricular Global Longitudinal Strain, EF CO SV EDV ESV
- Where
- 2 sites in China
- Volunteers
- 58 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Cardiac Surgery
Catecholamine-O-Methyl-Transferase(COMT)-Polymorphism in Cardiac Surgery
Although clinical risk factors for postoperative development of vasodilatory shock and acute renal failure have been identified; there is a considerable proportion of patients undergoing cardiac surgery where this syndrome cannot…
- Trial name
- NCT00334009
- Where
- Australia
- Volunteers
- 250 people
- Sponsor
- Austin Health
Postoperative Delirium, Postoperative Cognitive Dysfunction
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- CogCheck-Valid (NCT03360838)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 475 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Diseases
Impact of Preoperative Frailty and Cognitive Impairment on Postoperative Outcomes in Elderly Cardiac Surgery Patients
This is a retrospective study of patients aged 65 years and older who underwent cardiac and aortic surgery between March 5, 2021 and October 12, 2022 in the operating room of Severance Cardiovascular Hospital to determine the…
- Trial name
- NCT06330532
- Where
- South Korea
- Volunteers
- 447 people
- Sponsor
- Yonsei University
Transversus Thoracic Plane Block, Cardiac Surgery
Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery
The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are: 1.
- Conditions
- Transversus Thoracic Plane Block, Cardiac Surgery, Post Operative Pain
- Trial name
- NCT06546722
- Testing
- Transversus Thoracic Plane Block
- Where
- Lebanon
- Volunteers
- 150 people
- Sponsor
- Saint-Joseph University
Pain, Postoperative, Cardiac Surgery
Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery
The primary objective of this study is to determine if the addition of PECS2 block provides superior post-operative analgesia for cardiac surgery patients after midline sternotomy compared to only standard-of-care post-operative…
- Trial name
- NCT04282239
- Testing
- PECS2 block, Ropivacaine 0.5% Injectable Solution, Lidocaine Epinephrine
- Where
- United States
- Sponsor
- NYU Langone Health
Perioperative Complication, Perioperative/Postoperative Complications
Continuous vs Intermittent Monitoring of Respiratory and Heart Rate in Relation to Length of Stay
Is heart rate and respiratory rate measured continuously with a new wireless sensor better as compared to standard care, with manually measured spot checks by nurses on general wards? Does continuous monitoring detect more…
- Conditions
- Perioperative Complication, Perioperative/Postoperative Complications, Surgery-Complications
- Trial name
- CIM-LOS (NCT06973044)
- Testing
- Checkpoint Cardio wireless continuous monitoring device
- Where
- 2 sites in Sweden
- Volunteers
- 46 people
- Sponsor
- Karolinska Institutet
Quantitative Flow Reserve, Minimally Invasive Coronary Surgery
The Impact of Preoperative Quantitative Flow Reserve (QFR) on Early Postoperative Radial Artery Graft Outcomes in Coronary Artery Bypass Grafting
The goal of this observational study is to learn about the long-term effects of Quantitative Flow Reserve (QFR) assessment in patients undergoing Coronary Artery Bypass Grafting (CABG).
- Conditions
- Quantitative Flow Reserve, Minimally Invasive Coronary Surgery, Radial Artery
- Trial name
- QFR-RADIAL (NCT07669987)
- Testing
- Observational
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University Third Hospital
Rhinovirus, Congenital Heart Disease
'The Impact of Rhinovirus Infections in Paediatric Cardiac Surgery'
This is a prospective single- center observational study in the Leiden University Medical Center in approximately 250 children (<12 years) undergoing elective cardiac surgery, for congenital heart disease.
- Conditions
- Rhinovirus, Congenital Heart Disease, Respiratory Infections, Post-operative Complications
- Trial name
- RISK (NCT02438293)
- Testing
- rhinovirus diagnostics
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Leiden University
Atrial Fibrillation New Onset
Silymarin for the Prevention of Atrial Fibrillation After Cardiac Surgery
The study is a prospective, randomized, controlled trial to assess the effects of silymarin on the occurrence of postoperative atrial fibrillation after coronary artery bypass graft surgery.
- Trial name
- NCT06114719
- Testing
- Silymarin
- Where
- Serbia
- Volunteers
- 160 people
- Sponsor
- University of Novi Sad
Circulatory Perfusion Disorder, Congenital Heart Disease
Early Use of Vasopressin in Post-Fontan Management
This is an investigator initiated, prospective, single-center, double-blinded, randomized, placebo-controlled trial of post-operative low dose vasopressin infusions as an early treatment of low systemic perfusion in pediatric…
- Conditions
- Circulatory Perfusion Disorder, Congenital Heart Disease, Single-ventricle
- Trial name
- VAMP (NCT03088345)
- Testing
- Vasopressin, Arginine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Aortic Valve Stenosis, Regurgitation, Aortic
Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable CoreValve Evolut R or Evolut PRO System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprotheses. The 'LYTEN' Trial
The treatment with transcatheter aortic valve implantation (TAVI) of patients with small (≤23mm) surgical bioprostheses remains a challenge due to the increased transvalvular residual gradients and high rates of severe…
- Conditions
- Aortic Valve Stenosis, Regurgitation, Aortic, Prosthesis Failure
- Trial name
- NCT03520101
- Testing
- TAVI_ViV procedure with Edwards valve, TAVI_ViV procedure with CoreValve system
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Postoperative Delirium, Cardiac Surgical Procedures
Dynamic Multimodal Delirium Warning After Cardiac Surgery
After heart surgery, up to half of all patients may develop a state of sudden confusion called postoperative delirium. This condition can lead to longer time on a breathing machine, extended stays in the intensive care unit…
- Trial name
- DEW-POD (NCT07686900)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southeast University, China
Ischemia/Reperfusion Injury After Neonatal Cardiac Surgery, Inflammatory Reaction After Neonatal Cardiac Surgery
Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass
Around 7500 neonates born yearly in the United States have complex congenital heart disease that require surgical repair in the first few days of life.
- Trial name
- NCT02151877
- Testing
- Inhaled Nitric Oxide
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
The Cardiac Function
Postoperative Arrhythmia and Preoperative Cardiac Function
This study aims to investigate the association between echocardiographic parameters-including preoperative cardiac echo, as well as postoperative follow-up echocardiography and other associated parameters-and the risk factors…
- Trial name
- NCT06999681
- Testing
- No Interventions
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
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