Clinical trials: Post-operative Chronic Pain
Acute Pain, Chronic Pain
ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY
The main aim of our study was to test the hypothesis that Erector spine plane block (ESP) with sedation will provide the similar employment of fentanyl and propofol during surgery as an infiltrative local anaesthesia with…
- Conditions
- Acute Pain, Chronic Pain, Postoperative Pain, Anesthesia
- Trial name
- NCT05483647
- Testing
- Local infiltrative anaesthesia, Erector spine plane block
- Where
- Ukraine
- Volunteers
- 52 people
- Sponsor
- Lviv National Medical University
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Pain, Postoperative, Scoliosis Idiopathic
Gabapentin and Chronic Post Surgical Pain
The purpose of this study is to investigate the effect of a common pain medication (gabapentin) on chronic postsurgical pain in pediatric patients who require surgery for idiopathic scoliosis.
- Trial name
- CPSP (NCT03867240)
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- Emory University
Phantom Limb Pain
Evaluation of Neuroprosthesis with Sensory Feedback for Modulation of Phantom Limb Pain and Enhancing Quality of Life
This clinical trial is designed to assess the effectiveness of advanced neuromodulation techniques in reducing phantom limb pain by improving sensory feedback in bionic prostheses.
- Trial name
- NCT06702904
- Testing
- Peripheral Nerve Stimulation, Spinal cord stimulation, Dorsal Root Ganglion Stimulation
- Where
- 2 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Skolkovo Institute of Science and Technology
Potassium, Decreased Level, Postsurgical Pain, Chronic
Serum Potassium as a Predictor of Clinical Outcomes in an Older Patient Cohort With Chronic Postsurgical Pain
Perioperative serum potassium in patients over 65 impacts recovery, quality of life and physical functioning. While perioperative serum potassium is an important preoperative risk factor for poor surgical outcomes in older…
- Trial name
- NCT05385640
- Testing
- NO intervention
- Where
- China
- Volunteers
- 3,088 people
- Sponsor
- Chinese PLA General Hospital
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Chronic Pain
Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
The goal of this research proposal is to determine if the intraoperative administrative of Ketamine and Magnesium during laparoscopic gynecologic surgery improves postoperative pain in patients on chronic opioid therapy for…
- Trial name
- NCT02940509
- Testing
- Ketamine plus Magnesium sulfate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Post-Mastectomy Chronic Pain Syndrome
Dex & Mastectomy Pain
Chronic post-surgical pain is a common complication following mastectomy and represents a significant source of long-term morbidity.
- Trial name
- NCT07556952
- Testing
- Dexamethasone (intravenous), Normal Saline (0.9% NaCl)
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Phantom Limb Pain
Virtual Mirror Therapy for Relief of Chronic Phantom Limb Pain
The purpose of this project is to further investigate the use of Virtual Mirror therapy for alleviating symptoms of chronic phantom limb pain.
- Trial name
- NCT05194800
- Testing
- Virtual Mirror Therapy
- Sponsor
- University of Alabama at Birmingham
Post Operative Pain, Chronic
Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty
Pain is a major problem that has to be dealt with in case of hip fracture, as it presents an obstacle for examination, positioning for receiving neuroaxial anesthesia and postoperative mobility and physiotherapy.
- Trial name
- NCT05050487
- Testing
- PENG block, lumbar erector spinae plane block
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain, Video-Assisted Thoracoscopic Surgery
US-Guided ESPB Versus TPVB on Acute and Chronic Pain After VATS
Postoperative acute and chronic pain is frequently observed in patients undergoing video assisted thoracoscopic surgery (VATS). This prolongs the discharge time of patients and increases the frequency of postoperative pulmonary…
- Conditions
- Postoperative Pain, Video-Assisted Thoracoscopic Surgery, Thoracic Paravertebral Block, Erector Spinae Plane Block
- Trial name
- NCT04964401
- Testing
- Thoracic paravertebral block vs Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Chronic Post Surgical Pain, Functional Recovery
Incidence of Chronic Pain in Patients Undergoing Knee Arthroplasty Within a Fast-Track Protocol
The goal of this study is to learn about pain after knee replacement surgery. The surgery uses a fast-recovery program called Enhanced Recovery After Surgery (ERAS).
- Conditions
- Chronic Post Surgical Pain, Functional Recovery, ERAS, Chronic Opioid Use
- Trial name
- NCT07673276
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- University Hospital, Ghent
Acute Pain, Postoperative, Chronic Pain
Effect of Rebound Pain on Chronic Postsurgical Pain After Total Knee Arthroplasty
This prospective observational study aims to evaluate whether rebound pain after peripheral nerve block is associated with the development of chronic postsurgical pain following elective total knee arthroplasty.
- Conditions
- Acute Pain, Postoperative, Chronic Pain, Arthroplasty, Replacement, Knee
- Trial name
- NCT07511985
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Konya City Hospital
Chronic Postoperative Pain
Does a Multimodal no-Compression Suture Technique of the Intercostal Space Reduce Chronic Post-Thoracotomy Pain?
Chronic post-thoracotomy pain is a significant adverse outcome of thoracic surgery. transcollation technology evaluated with a prospective randomized trial the effect of a multimodal no-compression suture technique of the…
- Trial name
- NCT02630849
- Testing
- intercostal muscle flap and pericostal no-compression suture, Standard suture technique of the intercostal space
- Volunteers
- 380 people
- Sponsor
- University of Roma La Sapienza
Chronic Post-surgical Pain
Duloxetine to Prevent Chronic Postsurgical Pain After Inguinal Hernia Repair in Patients at High Risk
The clinical trial will be conducted in 14 Spanish hospitals. It is estimated, based on our previous studies, that 2855 patients scheduled for elective inguinal hernia surgery will have to be assessed to detect patients with ≥…
- Trial name
- GENDOLCAT3 (NCT06606067)
- Testing
- Duloxetine
- Where
- Spain
- Volunteers
- 294 people
- Sponsor
- Parc de Salut Mar
Chronic Apical Periodontitis
Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic Paste
This study aimed to evaluate the efficacy of N-acetylcysteine (NAC) used as an intracanal medicament on antibacterial activity, periapical RANKL/OPG ratio, and postoperative pain levels.
- Trial name
- NCT07340944
- Testing
- N Acetyl Cysteine, Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Chronic Pain, Failed Back Surgery Syndrome
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
Doctors sometimes treat chronic pain with devices that send mild electrical currents into the spinal cord. This type of treatment is referred to as neurostimulation.
- Conditions
- Chronic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes, Neuropathic Pain
- Trial name
- NCT04732325
- Testing
- Spinal cord stimulation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Michigan
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Inguinal Hernia
Safety and Effectiveness of Optomesh 3D for Inguinal Hernia Repair
OPTIMUS is an observational study assessing the safety and effectiveness of Optomesh 3D, a shaped surgical mesh used in planned keyhole surgery for a groin (inguinal) hernia.
- Trial name
- OPTIMUS (NCT07836179)
- Testing
- Optomesh 3D
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Swissmed Hospital
Breast Cancer, Chronic Pain
Effect of Perioperative CBT on Chronic Persistent Postsurgical Pain Among Breast Cancer Patients
Chronic persistent post-surgical pain (CPSP) is defined as pain at or near the site of surgery persisting for 3 months or more after the date of surgery.
- Conditions
- Breast Cancer, Chronic Pain, Chronic Postsurgical Pain, Quality of Life
- Trial name
- NCT04924010
- Testing
- Cognitive Behavioural Therapy (CBT), Education and Mindfulness
- Where
- Ireland
- Volunteers
- 48 people
- Sponsor
- Mater Misericordiae University Hospital