Clinical trials: Post-operative Chronic Pain
Inguinal Hernia, Adult
Comparison of Self Fixating Mesh to Mesh Fixation With Metallic Tacks in Laparoscopic Inguinal Hernia Repair
This study compares the use of self-fixating mesh to mesh fixation with tackers in the management of inguinal hernia by laparoscopic method.
- Trial name
- SELFITAC (NCT03564535)
- Testing
- Self fixating group, Tacker fixation group
- Where
- India
- Volunteers
- 112 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Opioid Use Disorder, Pain, Chronic
Adolescent Outcomes of Post-operative Opioid EXposure
The goal of this observational study is to examine the factors associated with the transition from medical exposure to opioids with "signposts" of future opioid use disorder among adolescent surgical patients.
- Trial name
- APEX (NCT06350409)
- Where
- 5 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Sharon Levy
Tonsillitis Chronic, Tonsillectomy
Tonsillectomy Using BiZact™ - a Randomized Side-controlled Clinical Trial
Tonsillectomies are frequently followed by severe postoperative pain, hence high analgetics consumption and prolonged hospitalization. Also, postoperative hemorrhages can be hazardous.
- Conditions
- Tonsillitis Chronic, Tonsillectomy, Hemorrhage, Postoperative Pain
- Trial name
- NCT03793816
- Testing
- BiZactTM Open Sealer/Divider
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Chronic Sinusitis
Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery
The purpose of this study is to assess the use of IV acetaminophen (Ofirmev) as a and safe and efficacious agent in reducing post-operative pain; we hypothesize that its use will reduce post-operative pain when compared to a…
- Trial name
- IVAPAP (NCT01608308)
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Health Science Center, Houston
Thoracic Surgery, Video-Assisted, Lidocaine
Lidocaine Infusion for Postthoracotomy Pain Syndrome
This study seeks to investigate lidocaine infusion to reduce postthoractomy pain syndrome after thoracic Surgery
- Conditions
- Thoracic Surgery, Video-Assisted, Lidocaine, Pain, Postoperative, Chronic Pain
- Trial name
- LIPPS (NCT03666299)
- Testing
- Lidocaine, Control
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Guangzhou First People's Hospital
Pain, Postoperative, Knee Pain Chronic
Ultrasound-guided Genicular Nerve Block for Total Knee Arthroplasty (GenTKR)
Knee Osteoarthritis affects one third of the population over 65 years old. Total knee arthroplasty (TKA) has become one of the most frequent surgical procedures in the world.
- Trial name
- GenTKR (NCT04024319)
- Testing
- Genicular Nerve Block
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Hospital Clinic of Barcelona
Chronic Pain, Acute Pain
Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs
The aim of this study is to evaluate the impact of intravenous lidocaine on acute and chronic post surgical pain on patients undergoing video assisted thoracoscopic surgery(VATS).
- Conditions
- Chronic Pain, Acute Pain, Neuralgia
- Trial name
- NCT02862769
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Apical Periodontitis
Evaluation of Post-Operative Pain Following the Use of Nano-Calcium Hydroxide
The goal of this clinical trial is to evaluate the effect of different intracanal medicaments-conventional calcium hydroxide (CH) and nano-sized calcium hydroxide (NCH)-on the intensity of postoperative pain following root canal…
- Trial name
- NCT07057336
- Testing
- Conventional Calcium Hydroxide (CH), Nanocalcium Hydroxide (NCH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cukurova University
Phantom Limb Pain, Postoperative Pain
Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Limb loss is frequently associated with postamputation pain that can be challenging to treat and often involves opioids. Advances in the field of neuromodulation has led to development of an intentionally reversible percutaneous…
- Conditions
- Phantom Limb Pain, Postoperative Pain, Neuroma, Acute Pain
- Trial name
- NCT03484429
- Testing
- Peripheral nerve stimulation, Standard Medical Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Pain, Acute, Pain, Postoperative
The Impact of Esmolol Administration on Postoperative Recovery
The aim of this study will be to investigate the effect of a continuous infusion of low dose esmolol on intraoperative and postoperative opioid consumption, as well as on postoperative recovery and chronic pain
- Conditions
- Pain, Acute, Pain, Postoperative, Pain, Chronic Post-Surgical, Esmolol
- Trial name
- esmolol (NCT05567822)
- Testing
- Esmolol Hydrochloride, normal saline
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
Total Knee Replacement, Post-operative Pain
Tapentadol vs Tramadol in Total Knee Arthroplasty
Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).
- Conditions
- Total Knee Replacement, Post-operative Pain, Chronic Pain
- Trial name
- NCT06269770
- Testing
- Tapentadol, Tramadol
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Thessaly
Chronic Post Surgical Pain
A Post Market Study to Assess the Spinal Modulation Dorsal Root Ganglion Stimulator System in Chronic Post Surgical Pain
20-SMI-2013 is a post market, observational, questionnaire based study to assess the effectiveness of the commercially available Axium neurostimulator in the management of chronic post surgical pain
- Trial name
- NCT02335229
- Testing
- Axium DRG Neurostimulator
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Abbott Medical Devices
Thyroid, Acute Pain
Ketamine in Robot-assisted Thyroidectomy
In this prospective double-blinded study, The investigators compared acute postoperative pain and rescue analgesic demand during postoperative period after robot thyroidectomy between ketamine and placebo groups.
- Conditions
- Thyroid, Acute Pain, Chronic Pain
- Trial name
- KEThyRobot (NCT01997801)
- Testing
- Ketamine infusion, NS infusion
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative, Chronic Pain
The Effect of Choice of Intraoperative Opioid on Postoperative Pain
The primary aim of this randomized, double-blind study is to examine the effect of a single intraoperative dose of methadone on postoperative pain and analgesic requirements in patients undergoing cardiac surgery with…
- Trial name
- NCT01542645
- Testing
- Methadone, Fentanyl
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Endeavor Health
Leiomyoma, Pelvic Organ Prolapse
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy.
- Conditions
- Leiomyoma, Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Chronic Pain
- Trial name
- TAP (NCT04172272)
- Testing
- Systemic multimodal analgesia administered intravenously, Transversus abdominis plane block (TAP block), Combined transversus abdominis plane block (TAP block) with systemic multimodal analgesia administered intravenously
- Where
- 2 sites in Croatia
- Volunteers
- 75 people
- Sponsor
- General Hospital Pula
Chronic Kidney Diseases, Post Operative Pain
Methadone Pharmacokinetics in End-stage Renal Disease
The goal of this observational study is to describe the influence of renal function on the pharmacokinetics of methadone used through an intravenous patient-controlled analgesia (IV-PCA) pump for the management of acute…
- Conditions
- Chronic Kidney Diseases, Post Operative Pain, Pain, Acute
- Trial name
- MCKD (NCT06056245)
- Testing
- Preoperative step, Intraoperative, Post-operative
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Chronic Postoperative Pain
Postoperative Pain After Ambulatory Arthroscopic Shoulder Surgery
Shoulder disorders are frequent, often associated with pain and occur in 7-34% of the general population and in 21% of the elderly population.
- Trial name
- NCT02924519
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Thoracotomy
Thoracotomy is frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain. Many factors such as postoperative analgesia treatment plan, operation time, number of chest tubes, and…
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, Thoracotomy
- Trial name
- NCT05177575
- Testing
- Thoracotomy application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Chronic Post-surgical Pain
Chronic Post Surgical Pain-Cardiac
The CPSP-Cardiac is a large, multi-center, observational study with the aim to investigate the incidence of chronic pain in the 3rd month postoperatively in cardiac surgery and its affecting factors.
- Trial name
- CPSP-Cardiac (NCT06382077)
- Where
- 29 sites in Turkey (Türkiye)
- Volunteers
- 2,442 people
- Sponsor
- Ondokuz Mayıs University
Persistent Pain, Postoperative Hyperalgesia
Prevention of Persistent Postsurgical Pain After Thoracotomy
Postthoracotomy acute pain is followed by persistent postsurgical pain in 20-30% of the patients, defined as pain that lasts more than 3-6 months after surgery.
- Trial name
- NCT01243801
- Testing
- Ketamine
- Where
- 2 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona