Clinical trials: Post-operative Chronic Pain
Neurosurgery
Superficial Cervical Plexus Block for Postoperative Chronic Pain
The incidence of postoperative chronic pain after craniotomy is high. Postoperative chronic pain seriously affects patient's quality of life. Compound local scalp nerve block is a good choice for analgesia after craniotomy.
- Trial name
- NCT05108337
- Testing
- Superficial cervical plexus block, Control group
- Where
- 2 sites in China
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Pain Measurement, Chronic Pain
Evaluation of Chronic Postsurgical Pain Risk in Patients Undergoing CIED Implantation Using an AID Support System
Chronic postsurgical pain (CPSP) remains a significant clinical and public health challenge despite major advances in surgical and anesthetic techniques.
- Conditions
- Pain Measurement, Chronic Pain, Cardiac Implantable Electrical Devices, Neuropathic Pain
- Trial name
- PAIN-AID (NCT07322900)
- Volunteers
- 180 people
- Sponsor
- Istanbul University - Cerrahpasa
Post Operative Pain
Postoperative Pain After Using Different Single-File Glide Path Systems
This study aimed to evaluate postoperative pain intensity after glide-path preparation with the ProGlider (PG) and WaveOne Gold Glider (WOGG) systems in asymptomatic teeth with necrotic pulp and periapical lesions.Maxillary and…
- Trial name
- NCT05955742
- Testing
- Control, ProGlider, WaveOne Gold Glider
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Post Surgical Pain, Post Operative Pain
Chronic Postsurgical Pain: Multivariate Prediction Model
The goal of this observational study is to identify the risk factors of Chronic Postoperative pain (or Chronic Post Surgery Pain - CPSP) three months after surgery and, subsequently.
- Conditions
- Post Surgical Pain, Post Operative Pain, Postoperative Pain, Chronic
- Trial name
- CPoP (NCT06417528)
- Testing
- Chronic Post Surgery Pain (CPSP)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Phantom Limb Pain, Residual Limbs
Focused Ultrasound Treatment of Stump Neuromas for the Relief of Chronic Post-Amputation Neuropathic Pain
AIM: To provide initial information on the efficacy (pain reduction) and safety of focused ultrasound surgery for the ablation of stump neuromas in amputees with chronic neuropathic pain.
- Conditions
- Phantom Limb Pain, Residual Limbs, Amputation
- Trial name
- NCT03255395
- Testing
- Magnetic resonance-guided focused ultrasound
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rambam Health Care Campus
Chronic Pain, Complex Regional Pain Syndrome
Effects of Spinal Cord Stimulation on Sensory Perceptions of Chronic Pain Patients
It's well known that Spinal cord stimulation (SCS) changes the perception of chronic pain in the area stimulated by epidural electrodes.
- Conditions
- Chronic Pain, Complex Regional Pain Syndrome, Failed Back Surgery Syndrome
- Trial name
- NCT02837822
- Testing
- Spinal cord stimulator, Implantation of a spinal cord stimulator
- Where
- 2 sites in United States, Canada
- Volunteers
- 38 people
- Sponsor
- CHU de Quebec-Universite Laval
Failed Back Surgery Syndrome, Spinal Cord Stimulation
Impact of the SCS With Different Waveforms Over the Quality of Life (SCS-Quality)
Prospective, randomized, multicentre, parallel, controlled, and double-blind trial. It is a study with 2 groups with evaluation pre and post treatment with Spinal Cord Stimulation (SCS) implantation of patients with Failed Back…
- Trial name
- SCS-Quality (NCT04244669)
- Testing
- IPG with Conventional Stimulation, IPG with SCS DTM
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Pablo López Pais
Acute Postoperative Pain, Chronic Postoperative Pain
Femoral and Epidural Block After Total Knee Arthroplasty
Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control.
- Trial name
- NCT02115945
- Testing
- DN4 test, The SF 12 test, HAD scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pain, Postoperative
Observational Study of an Automatic Detection of Patients at Risk of Chronic Postoperative Pain ("Alerte Douleur")
Following surgery, some but not all patients develop persistent (or chronic) postoperative pain CPSP. Several risk factors for this persistent pain have been confirmed in previous studies, but neither surgeons nor…
- Trial name
- ALDO (NCT03164954)
- Testing
- automatic risk detection
- Where
- Switzerland
- Volunteers
- 355 people
- Sponsor
- Benno Rehberg-Klug
Pain, Postoperative, Anxiety Preoperative
The Efficacy of a Mindfulness-Based Virtual Reality Intervention to Reduce Pain in Postoperative Patients
The goal of this randomized clinical trial is to evaluate whether a virtual reality (VR) mindfulness intervention can reduce anxiety and postoperative pain in adults undergoing surgery, primarily hernia and varicose vein…
- Trial name
- VR-MindPain (NCT06961695)
- Testing
- VR Mindfulness-Based Relaxation
- Volunteers
- 64 people
- Sponsor
- Babes-Bolyai University
Perioperative Pain in Robotic Prostatectomy
Tramadol / Magnesium in Ropivacaine Solution in UG-bilateral TAP Block and Analgesia in Robotic Radical Prostatectomy
Tramadol and magnesium have already been researched in recent decades for their different roles in pain control. This clinical study will compare and re-evaluate their effect on the duration and quality of analgesia provided by a…
- Trial name
- NCT07289321
- Testing
- Ultrasound - guided bilateral transversus abdominis plane block (TAP) in patients undergoing robotic-assisted radical prostatectomy.
- Where
- Greece
- Volunteers
- 105 people
- Sponsor
- Aretaieion University Hospital
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Chronic Rhinosinusitis (Diagnosis)
Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery
The safest and most effective post-operative pain control regimen after functional endoscopic sinus surgery (FESS) has been the subject of persistent research.
- Trial name
- NCT05287217
- Testing
- Comparison of medication administration for pain control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Post Traumatic Chronic Pain
The Biopsychosocial Model to Identify Risk Factors for Chronic Postoperative Pain in Orthopedic Trauma Surgery Patients
This study aims to assess multidimensional risk factors for chronic post-traumatic pain in orthopedic trauma surgery patients. The purpose is to better understand pain chronification mechanisms by quantifying the interaction…
- Trial name
- TRAUMA PAIN (NCT07685184)
- Testing
- • biological collection
- Volunteers
- 600 people
- Sponsor
- University Hospital, Montpellier
Phantom Limb Pain, Pain, Chronic
Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain
Controlled clinical trial of two parallel groups, with random assignment 1:1, non-inferiority, blinded for the patient, for who administers the intervention and for who analyzes the data. 112 participants
- Trial name
- Ampupain (NCT05608733)
- Testing
- Epidural catheter, Continuous sciatic nerve block
- Where
- Colombia
- Volunteers
- 112 people
- Sponsor
- Universidad de Antioquia
Chronic Rhinosinusitis (CRS), Emergence Agitation
Trans-nasal Sphenopalatine Ganglion Block for Prevention of Emergence Agitation Following Functional Endoscopic Sinus Surgery
This randomized double-blind controlled trial aims to evaluate whether bilateral trans-nasal sphenopalatine ganglion block (SPGB) using bupivacaine reduces the incidence of emergence agitation following Functional Endoscopic…
- Trial name
- SPGB-EA (NCT07645521)
- Testing
- Bilateral Trans-nasal Sphenopalatine Ganglion Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Acute Post-operative Pain, Chronic Post Operative Pain
Duloxetine Impact on Postoperative Pain Control and Outcomes
1. Evaluate differences between patients taking Duloxetine or placebo following lateral lumbar interbody fusion for postoperative narcotic consumption. 2.
- Conditions
- Acute Post-operative Pain, Chronic Post Operative Pain, Narcotic Use, Opioid Use
- Trial name
- NCT05611749
- Testing
- Duloxetine 60 MG
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Cardiac Surgery
Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Sternotomy
Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%.
- Trial name
- NCT05885230
- Testing
- pecto intercostal fascial block using bupivacaine 0.25%, lidocaine infusion
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Inguinal Hernia, Postoperative Pain
Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal hernia repair is one of the most frequently performed operations in young men. Persistent pain after inguinal surgery represents a significant cause of disability, occurring in between 15%-35% of cases.
- Trial name
- NCT00825344
- Testing
- Etanercept, Saline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University