Clinical trials: Post-operative Chronic Pain
Hysterectomy, Chronic Pain
Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy
Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete…
- Conditions
- Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression
- Trial name
- EPOCH (NCT04014829)
- Testing
- Pain-Pressure Threshold, Mechanical Temporal Summation, Hospital Anxiety and Depression Scale
- Where
- Singapore
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Pain, Chronic, Pain, Neuropathic
Caregiver Burden and Correlation With Clinical Outcome in Spinal Cord Stimulation for Chronic Neuropathic Pain
Prospective multicentric observational trial on caregiver burden, caregiver satisfaction and clinical outcome in spinal cord stimulation for chronic neuropathic pain.
- Conditions
- Pain, Chronic, Pain, Neuropathic, Failed Back Surgery Syndrome
- Trial name
- CAREstim (NCT04737746)
- Where
- 2 sites in Belgium
- Volunteers
- 42 people
- Sponsor
- AZ Delta
Breast Cancer, Pain
Psychological and Social Factors and Risk Chronic Pain After Surgery in Women With Breast Cancer
Certain psychological and social factors may increase the risk of developing chronic pain after surgery. Evaluating these factors over time in patients who have undergone surgery for breast cancer may help doctors plan treatment…
- Conditions
- Breast Cancer, Pain, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- SDPM (NCT00466830)
- Testing
- questionnaire administration, management of therapy complications, psychosocial assessment and care
- Sponsor
- Institut Bergonié
Cerebral Palsy, Chronic Post Surgical Pain
Chronic Postsurgical Pain
The study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors for the development of chronic postsurgical pain.
- Trial name
- CPSP (NCT05764681)
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Chantel Burkitt
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Exploring the effects of repeated transcranial magnetic stimulation (rTMS) during the perioperative period on the incidence of postoperative delirium, postoperative cognitive dysfunction, and chronic postoperative pain in elderly…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Chronic Post-surgical Pain
- Trial name
- NCT06392919
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Affiliated Hospital of Nantong University
Chronic Shoulder Pain
Exparel for Total Shoulder Pain
Total shoulder surgery (arthroplasty) is a widely successful method of treating shoulder arthritis. Although the goal of the procedure is pain relief, post-operative pain is unavoidable.
- Trial name
- ETSP (NCT03739021)
- Testing
- Exparel, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Ilioinguinal Nerve Section, Pain Prevention
Prophylactic Ilioinguinal Neurectomy During Open Tension-Free Inguinal Hernia Repair
postoperative chronic inguinal pain is a common postoperative complication after open inguinal hernia repair. Chronic inguinal pain is a common complication following open inguinal hernia repair.
- Conditions
- Ilioinguinal Nerve Section, Pain Prevention, Hernioplasty
- Trial name
- NCT06327763
- Testing
- ilioinguinal nerve section
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Chronic Postoperative Pain
Validation of Predictive Scale of Chronic Postsurgical Pain
To asses the precision of a score to predict chronic post surgical pain in patients undergoing inguinal hernia repair, abdominal hysterectomy, vaginal hysterectomy and thoracotomy.
- Trial name
- NCT02991287
- Testing
- Inguinal hernia repair, Abdominal hysterectomy, Vaginal hysterectomy
- Where
- 21 sites in Spain
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Chronic Pain, Postoperative, Sternotomy Pain
Early Screening of Chronic Post-sternotomy Pain Using the DN4-i Questionnaire
Chronic post-sternotomy pain (CPSP) is a common complication after cardiac surgery, with a reported prevalence between 30% and 50%.
- Trial name
- DEPDN4i (NCT07603271)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institute Arnault Tzanck, France
Breast Cancer, Breast Cancer Female
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
The LOLIPOP Trial is a large (n=4,300 patients) pragmatic, international, multicentre, prospective, randomised, double blind, placebo-controlled, parallel assessment, safety and effectiveness superiority study.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Conserving Surgery, Mastectomy
- Trial name
- LOLIPOP (NCT05072314)
- Testing
- lidocaine 2% and 10%
- Where
- 49 sites in Australia, Hong Kong and 2 more
- Volunteers
- 4,300 people
- Sponsor
- Monash University
Pain, Chronic Postsurgical, Knee Osteoarthritis
Central Sensitization in Total Knee Arthroplasty Patients with Persistent Pain
Persistent post-surgical pain is a significant adverse effect after total knee arthroplasty, present in around 20% of the patients. Central sensitization may contribute to developing and maintaining pain.
- Conditions
- Pain, Chronic Postsurgical, Knee Osteoarthritis, Sensitization, Central
- Trial name
- NCT05575310
- Testing
- Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- University of Barcelona
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
Endometriosis, Post Operative Pain
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain…
- Trial name
- NCT05229653
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Chronic Pain Post-Procedural
Block REducing Pain After Surgery Trial
This observational study evaluates difference in chronic pain after six months from surgery between patients who received PECS block and general anesthesia versus general anesthesia alone.
- Trial name
- BREAST (NCT03448913)
- Testing
- PECS block
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- University of Padova
Chronic Pain, Tissue Adhesion
Laparoscopic Adhesiolysis for Chronic Abdominal Pain Revisited
Chronic abdominal and pelvic pain is a common complaint following peritoneal surgery, affecting 20-40% of patients. Adhesions account for 60% of chronic postoperative pain cases, suggesting that adhesiolysis can play an important…
- Trial name
- NCT02983916
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Radboud University Medical Center
Chronic Post-surgical Pain
Transversus Abdominis Plane Block for Chronic Postsurgical Orchalgia
the study will evaluate the effect of transversus abdominis plane block (TAP) on chronic post-groin surgeries orchalgia (chronic testicular pain)
- Trial name
- NCT03525938
- Testing
- TAP block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Pain, Postoperative
Effect of Ketamine on Analgesia Post-Cardiac Surgery
Randomized, controlled, double-blind pilot study evaluating the effect of an intraoperative infusion of intravenous Ketamine on the quantity of opioid consumed postoperatively in coronary artery bypass surgery patients receiving…
- Trial name
- NCT02925858
- Testing
- Normal Saline Flush, 0.9% Injectable Solution_#1, Ketamine Hydrochloride
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Jewish General Hospital
Chronic Post-Surgical Pain
Effect of Perioperative Sleep Quality on Chronic Post-Surgical Pain
The goal of this prospective observational cohort study is to assess the impact of perioperative sleep quality on the development of chronic post-surgical pain (CPSP) in adult patients (aged 18-80 years, ASA I-III) undergoing…
- Trial name
- NCT06871891
- Where
- China
- Volunteers
- 1,138 people
- Sponsor
- Peking Union Medical College Hospital
Surgery
Collecting Outcomes and Managing Pain After Surgery
The primary aim of this study is to measure pain and psychosocial patient reported outcomes, objective functionality, and actual daily at home opioid usage in orthopedic patients.
- Trial name
- COMPAS (NCT03834818)
- Testing
- COMPAS Participants
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Duke University
Postoperative Chronic Pain
Effect of Esketamine and Lidocaine on Postoperative Chronic Pain and Long-term Survival in Patients Undergoing Hepatectomy
This study is a further observation and follow-up of the patients enrolled in the registration number ChiCTR230007164430 to further evaluate the effect of long-term infusion of esketamine and lidocaine on postoperative chronic…
- Trial name
- NCT06778460
- Testing
- Esketamine-lidocaine group
- Where
- China
- Volunteers
- 304 people
- Sponsor
- West China Hospital