Clinical trials: Post-operative Chronic Pain
Pain
Patient Controlled Analgesia Pharmacogenetic Study
The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop…
- Trial name
- NCT01731873
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Postherniotomy Pain
Predisposing Factors for Chronic Postherniotomy Pain
Chronic pain affects pain in 5-8% of patients more than a year after groin hernia repair. However no prospective study has investigated potential predisposing factors for development of pain, including genetic, psychosocial and…
- Trial name
- NCT00649142
- Testing
- Open sutured mesh repair, Laparoscopic mesh glue fixation
- Where
- 2 sites in Denmark, Germany
- Volunteers
- 455 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Knee Pain Chronic
Chronic Pain and Functional Prognosis After Total Knee Replacement: Continuous Locoregional Analgesia by Catheter to the Femoral Triangle Versus Tissue Infiltration as Part of an Improved Rehabilitation After Surgery Approach
The prevalence of Chronic Post-Surgical Pain (CPSP) after knee replacement, defined as pain greater than or equal to 4/10 on the visual analogue scale after the third postoperative month, is recognised as high, with an average of…
- Trial name
- TKAFTER (NCT03998813)
- Testing
- Ropivacaine
- Where
- 5 sites in France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Postoperative Chronic Pain
Intravenous Lidocaine on Chronic Pain in Patients Undergoing Hepatectomy
This study is a further observation and follow-up of the patients enrolled in the registration number NCT04295330 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality…
- Trial name
- NCT05492669
- Testing
- Lidocaine Hydrochloride, Injectable, 0.9% normal saline
- Where
- China
- Volunteers
- 260 people
- Sponsor
- West China Hospital
Surgical Procedures, Operative, Pain
Evaluation of Pain Trajectories After Surgery and Their Potential Relationship With Chronicity at 3 Months
The effective management of acute postoperative pain remains a daily challenge despite the organizational efforts made and the techniques put in place.
- Conditions
- Surgical Procedures, Operative, Pain, Chronic Pain
- Trial name
- ETADOL (NCT05326737)
- Testing
- In hospital pain evaluation, In hospital questionnaires, Telephone contact at 3 months
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Renal Failure Chronic, Surgery
Methadone Anesthesia For Kidney Transplant Receptors
Intraoperative methadone or fentanyl will be administered to patients submitted to kidney transplant surgery. Postoperative pain, analgesic consumption and side effects will be evaluated
- Trial name
- NCT04908345
- Testing
- Methadone, Fentanyl
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Postoperative Pain
euCPSP: European Observational Study on Chronic Post Surgical Pain,PAIN-OUT Study
This project a European observational study on the incidence and characteristics of chronic post surgical pain (CPSP). Research Questions What is the incidence of chronic post surgical pain (CPSP) in Europe? What are the risk…
- Trial name
- PAIN-OUT (NCT01467102)
- Where
- 24 sites in Belgium, France and 9 more
- Volunteers
- 3,618 people, healthy volunteers welcome
- Sponsor
- European Society of Anaesthesiology
Opioid Use, Opioid Dependence
Can Simplified and More Detailed Instructions Affect Post-Operative Narcotic Consumption
This project intends to investigate whether (1) a patient-maintained opioid diary provides an accurate measure of opioid consumption (morphine equivalents), (2) improved patient educational materials decrease narcotic…
- Conditions
- Opioid Use, Opioid Dependence, Knee Pain Chronic, Knee Osteoarthritis
- Trial name
- NCT03534102
- Testing
- Improved Opioid-Tapering Instructions, Clinical Patient Educator
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain, Back Pain Lower Back Chronic
Magnesium Sulfate Infusion on Postoperative Pain in Lumbar Surgery
Effective postoperative analgesia after lumbar spine surgery (e.g., laminectomy, vertebroplasty, lumbar stabilization) is associated with faster recovery and shorter hospital stay.
- Trial name
- NCT07418580
- Testing
- Magnesium sulfate, normal saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Post-thoracotomy Pain
Does Peri-Operative Gabapentin Reduce Chronic Post-Thoracotomy Pain?
The primary objective of this study is to determine if gabapentin can decrease or prevent chronic post-thoracotomy pain.
- Trial name
- NCT00934193
- Testing
- Gabapentin
- Sponsor
- University of Kansas Medical Center
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Breast Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT03124511
- Testing
- Surgery for breast cancer
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Danish Pain Research Center
Chronic Postsurgical Pain
Clinical Prediction Model and External Validation of Chronic Postsurgical Pain in Elders
This study will collect perioperative pain-related data of elderly patients in multi-centers. Analyzing these collected data to find the high-risk factors of chronic postsurgical pain in elderly patients and to establish an…
- Trial name
- NCT05372406
- Testing
- • no intervention
- Where
- China
- Volunteers
- 7,770 people
- Sponsor
- Chinese PLA General Hospital
Inguinal Hernia, Inguinal Hernia Repair
Comparative Study of Inguinodynia After Inguinal Hernia Repair
To evaluate the postoperative pain and the relapse after the repair of the inguinal hernia by Lichtenstein technique with four different mesh types with different types of fixation in patients undergoing major ambulatory surgery.
- Conditions
- Inguinal Hernia, Inguinal Hernia Repair, Open Inguinal Hernia
- Trial name
- NCT03678272
- Testing
- HERNIOPLASTY WITH PANAVALE MESH, HERNIOPLASTY WITH PARIETEX PROGRIP MESH, HERNIOPLASTY WITH ADHESIX MESH
- Volunteers
- 270 people
- Sponsor
- Hospital General Universitario Elche
Chronic Postoperative Pain
Dexmedetomidine for Prevention of Chronic Postoperative Pain
Chronic postoperative pain (CPSP) is common symptom in patients after surgery, seriously affected the quality of life. Accumulating evidences have demonstrated dexmedetomidine can improve chronic pain.
- Trial name
- NCT03275207
- Testing
- saline, dexmedetomidine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhongda Hospital
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Failed Back Surgery Syndrome
A Post Market Study on DRG Stimulation in FBSS (SYMPATHY)
The purpose of this Post Market Observational Study is to monitor the effect of the Axium® SCS System in the management of chronic pain following surgical lumbar discectomy in subjects whom are routinely scheduled for treatment…
- Trial name
- NCT02634398
- Where
- Switzerland
- Sponsor
- Abbott Medical Devices
Analgesia, Post Operative Pain
Morphine vs Sufentanil PCA: Same Same or Different?
Patient-controlled intravenous analgesia (PCA) has already proven its quality. However, with new strategies starting to emerge and the current concept of opioid sparing, it is a goal to find the optimal PCA strategy capable of…
- Conditions
- Analgesia, Post Operative Pain, Patient Satisfaction, Chronic Pain
- Trial name
- NCT05259098
- Testing
- Sufentanil Sublingual Tablet System, Intravenous Patient-Controlled Analgesia with morfine
- Where
- Portugal
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Failed Back Surgery Syndrome, CRPS (Complex Regional Pain Syndromes)
Comparison of Effectiveness of Tonic, High Frequency and Burst Spinal Cord Stimulation in Chronic Pain Syndromes
Spinal cord stimulation (SCS) is one of the most commonly undertaken neuromodulatory surgery techniques in the treatment of neuropathic pain.
- Trial name
- NCT03957395
- Testing
- Device: Precision Novi™ system Neurostimulation procedures
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Jan Biziel University Hospital No 2 in Bydgoszcz
Inguinal Hernia, Femoral Hernia
Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations
The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia…
- Conditions
- Inguinal Hernia, Femoral Hernia, Umbilical Hernia, Ventral Hernia
- Trial name
- NCT05920200
- Testing
- open non-mesh hernia repair, open mesh hernia repair, MIS hernia repair
- Where
- Russia
- Volunteers
- 4,000 people
- Sponsor
- Immanuel Kant Baltic Federal University