Clinical trials: Post-operative Nausea
Microvascular Decompression Surgery, Postoperative Nausea and Vomiting
Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery
Postoperative nausea and vomiting (PONV) is a common problem and may lead to catastrophic complications, especially in neurosurgical cases.
- Trial name
- NCT03685032
- Testing
- Dexamethasone, Ondansetron, 0.9% Sodium Chloride Injection
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Khon Kaen University
Anesthesia, Pain, Postoperative
Effect of Erector Spinae Plane Block on Postoperative Nausea and Vomiting
This study will investigate the hypothesis that preoperative erector spinae plane (ESP) block will reduce the incidence of postoperative nausea and vomiting (PONV) in patients undergoing elective lumbar disc herniation (LDH)…
- Conditions
- Anesthesia, Pain, Postoperative, Nausea and Vomiting, Postoperative
- Trial name
- NCT06710457
- Testing
- ESP, No ESP
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Ankara City Hospital Bilkent
Cesarean Section Complications, Pain
Intraabdominal Chloroprocaine During Cesarean Delivery for Pain Control
Objective The objective of this study is to test the hypothesis that instillation of intra-abdominal chloroprocaine during cesarean deliveries is associated with decreased postoperative pain and nausea compared to placebo…
- Trial name
- NCT03260972
- Testing
- Chloroprocaine Hcl 2% Inj, Normal saline
- Sponsor
- Johns Hopkins University
Postoperative Nausea and Vomiting
Study of APD421 as PONV Treatment (no Prior Prophylaxis)
Double-blind, randomised, parallel-group, placebo-controlled, adaptive, seamless, dose-selecting study to compare the efficacy of APD421 to placebo as treatment of established PONV, in patients who have not had prior PONV…
- Trial name
- NCT02449291
- Testing
- APD421
- Where
- 4 sites in United States, France and 1 more
- Volunteers
- 568 people
- Sponsor
- Acacia Pharma Ltd
Postoperative Nausea and Vomiting
Effect of Aromatherapy on Postoperative Nausea, Vomiting
The aim of this study is to evaluate the effect of the aromatherapy with lavender, rose or ginger essential oils on nausea, vomiting and postoperative quality of recovery scores in patients with postoperative nausea and vomiting.
- Trial name
- NCT02732379
- Testing
- Lavender Aromatherapy, Rose Aromatherapy, Ginger Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people
- Sponsor
- Tokat Gaziosmanpasa University
Postoperative Nausea, Postoperative Vomiting
Influence of Monitoring the Depth of General Anesthesia Upon the Incidence of PONV and Emergence Delirium in Children Undergoing Endoscopic Adenoidectomy in General Anesthesia
The study has been designed as a prospective randomized clinical trial. Due to the use of a bispectral (BIS) monitor in the interventional arm, the study will not be blinded for the anesthetist.
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Emergence Delirium
- Trial name
- NCT04466579
- Testing
- BIS monitor, Standard care
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Postoperative Nausea and Vomiting (PONV)
Dexamethasone for Prevention of Postoperative Vomiting After Laparoscopic Gynecologic Surgery
Postoperative nausea and vomiting (PONV) are common and distressing complications following laparoscopic gynecologic surgery. This randomized controlled trial evaluated whether a single preoperative intravenous dose of…
- Trial name
- PONV-DEX-GYN (NCT07421817)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Rawalpindi Medical College
Palonosetron
Comparison of the Efficacy of Acupressure P6 Point, Dexamethasone and Ondansetron Versus Palonosetron Monotherapy for Preventing Postoperative Nausea and Vomiting in Laparoscopic Surgery
Postoperative nausea and vomiting (PONV) is defined as nausea and/or vomiting occurring within 24 hours after surgery, it commonly affects 20-30% patients but as high as 70-80% patients who are deemed high risk for PONV may be…
- Trial name
- NCT04461093
- Testing
- Acupressure wristband and Palanosetron
- Where
- 2 sites in Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mohd Zulfakar Mazlan, MBBS
Postoperative Nausea and Vomiting
Dexamethasone, Can it Replace Ketoprofen in the Strategy of Intraoperative Multimodal Analgesia in Paediatric Surgery ? A Prospective Randomized Double-blinded Study. DEXA OP
Postoperative pain and nausea-vomiting (PONV) are the first causes of failure in ambulatory care in pediatric surgery. Actually, the paracetamol/ketoprofen combination in intraoperative care is recommended for effective…
- Trial name
- DEXA OP (NCT02400047)
- Testing
- Dexamethasone 0.2 mg/kg, Dexamethasone 0.4 mg/kg, Ketoprofen 1 mg/kg
- Where
- France
- Volunteers
- 580 people
- Sponsor
- Rennes University Hospital