Clinical trials: Post-operative Pain
Perioperative Inflammatory Response, Postoperative Pain
Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
the aim is to determine the value of adding bilateral supra zygomatic maxillary nerve block to general anesthesia in attenuating the systemic inflammatory response in paediatrics.
- Trial name
- NCT05495750
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alaa Mohamed Abdel Salam Ibrahim Soliman
Postoperative Pain, Acute, Anaesthetic
Analgesic Effect of Intraoperative Intravenous S-Ketamine During Total Knee Arthroplasty Surgery
Severe acute pain after total knee arthroplasty surgery has multiple implications for hospitals and patients, monopolising resources and affecting the quality of life.
- Trial name
- NCT05289050
- Testing
- sodium chloride (NaCl; 0.9%), S-ketamine
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Ling Dong
Pain, Postoperative
Effect of Preincisional Bupivakain Infiltration on Postoperative Narcotic Medication Requirement
Postoperative pain and use of narcotic analgesics after laparoscopic bariatric surgeries are problems that need to be solved in terms of patient comfort.
- Trial name
- NCT03071991
- Testing
- study group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Thoracoscopic Lobectomy
Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management
Phase Ⅱ, randomized, double-blind, comparator-controlled study to evaluate the efficacy, safety and pharmacokinetics of single injection intercostal nerve block with HR18034 for postoperative pain management compared with…
- Trial name
- NCT05744674
- Testing
- HR18034, Ropivacaine Hydrochloride Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Post-operative Pain
Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control
Both single shot femoral nerve block and continuous femoral nerve block with catheter have been shown to be effective for pain control after anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT01916590
- Testing
- Bupivicaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Colorado, Denver
Anxiety, Pain, Postoperative
Postoperative Effects of Preoperative Anxiety
INTRODUCTION Patients who will have obesity surgery have about %48 psychiatric illnesses like anxiety disorder. Studies which analyze the relationship between preoperative anxiety level and postoperative pain had reported…
- Trial name
- NCT04432558
- Testing
- Spielberger's State-Trait Anxiety Inventory, Visual analog scale, Ramsay's sedation scale, Tramadol, paracetamol, diclofenac sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pain, Postoperative, Pain, Chest
Ideal Initial Bolus and Infusion Rate for Erector Spinae Plane Block Catheters
This study would like to identify the best starting dose and infusion rate for nerve blocks and nerve catheters related to the erector spinae plane block that can improve functional status and pain control on cardiac surgery…
- Trial name
- NCT03961048
- Testing
- Ropivacaine 0.2%-Sodium Chloride 0.9% Injectable Solution bilaterally, Ropivacaine 0.2%-Sodium Chloride 0.9% Injectable Solution unilaterally
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Pain, Postoperative, Acute Pain
Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy
The purpose of this phase 3 study is to evaluate the efficacy and safety of VVZ-149 Injections for the treatment of postoperative pain following laparoscopic colectomy.
- Trial name
- NCT05764525
- Testing
- VVZ-149 Injections
- Where
- 5 sites in South Korea
- Volunteers
- 285 people
- Sponsor
- Vivozon Pharmaceutical Inc.
Postoperative Pain, Cesarean Section
Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune…
- Conditions
- Postoperative Pain, Cesarean Section, Wound Heal
- Trial name
- NCT05840406
- Testing
- Postoperative pain management with acetaminophen, Bilateral TAP Block with levobupivacaine, Bilateral TAP Block with levobupivacaine and dexmedetomidine
- Where
- Croatia
- Volunteers
- 105 people
- Sponsor
- University Hospital Sestre Milosrdnice
Knee Osteoarthritis, Pain, Postoperative
Influence of Patient Sex on Pain Control and Multimodal Analgesia in Total Knee Arthroplasty
The purpose of this study is to examine the influence of sex on postoperative pain, following total knee arthroplasty (TKA). Patients will first be stratified by sex and then be randomized into one of two multimodal analgesic…
- Trial name
- NCT04471233
- Testing
- Multimodal analgesia including pregabalin, Multimodal analgesia not including pregabalin
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Northwell Health
Post Operative Endodontic Pain
Reduction of Post-operative Endodontic Pain
To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.
- Trial name
- NCT01480752
- Testing
- Lornoxicam, normal saline, no injection
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Hernioplasty, Cholecystectomy, Laparoscopic
Intensive Monitoring of Post-surgery Pain in Major Ambulatory Surgery
Moderate to severe acute postoperative pain (APP) during part of the postoperative period is a barrier that hinders the central objective of perioperative medicine, which is to achieve an optimal postoperative recovery process.
- Conditions
- Hernioplasty, Cholecystectomy, Laparoscopic, Haemorrhoidal Surgery, Knee Arthroscopy
- Trial name
- NCT07252817
- Testing
- Intensive monioring group, Standard monitoring group
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Consorci Sanitari del Maresme
Postoperative Pain
Effectiveness of Magnetic Therapy on Pain Intensity
Static magnetic therapy is increasingly used to alleviate pain; however, its efficacy has not been determined yet. The aims of this proposal are to evaluate the effect of magnetic therapy on pain intensity levels, opioid…
- Trial name
- NCT00104533
- Testing
- Magnets
- Where
- Colombia
- Volunteers
- 164 people
- Sponsor
- Javeriana University
Pain, Postoperative, Anesthesia
Oral Methadone in Cardiac Surgery
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac…
- Conditions
- Pain, Postoperative, Anesthesia, Cardiac Surgery
- Trial name
- OMICS (NCT07221617)
- Testing
- Methadone, oral, Methadone, intravenously
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Post Operative Pain, Acute
Bupivacaine Alone vs Bupivacaine With Tramadol in Local Anesthesia Procedures
This study looked at two different medicines used during local anesthesia to control pain after surgery. Investigators compared bupivacaine alone with bupivacaine mixed with tramadol.
- Trial name
- NCT07469826
- Testing
- Tramadol, Bupivacaine
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Post Operative Pain, Acute, Arthroscopic Shoulder Surgery
Comparison Between Dexametidomedine\Bupivacaine and Plain Bupivacaine in Superior Trunk Block for Arthroscopic Shoulder Surgeries
Comparison between dexametidomedine\bupivacaine and plain bupivacaine in superior trunk block for arthroscopic shoulder surgeries
- Trial name
- NCT07046325
- Testing
- dexametedomidine, Bupivacain
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Pain, Postoperative
Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management…
- Trial name
- NCT04349774
- Testing
- Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Uskova
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University