Clinical trials: Post-operative Pain Control
Pain, Postoperative
Toradol v. Celecoxib for Postoperative Pain
Randomized control trial between ketorolac versus celecoxib for postoperative pain following hysterectomy.
- Trial name
- POP (NCT03331315)
- Testing
- Celecoxib, Ketorolac
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Michael Ulm, MD
Post Operative Pain, Knee Osteoarthritis
Cryoneurolysis Prior to Total Knee Arthroplasty
Knee osteoarthritis is a major issue worldwide with limited treatment options. Many patients receive knee joint replacement surgery which is considered effective and safe.
- Conditions
- Post Operative Pain, Knee Osteoarthritis, Opioid-Related Disorders
- Trial name
- NCT05840276
- Testing
- Cryoneurolysis
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Ankle Fracture
Exparel and Ankle Surgery
This study involves a drug called Exparel that has been approved by the US Food and Drug Administration (FDA), for application directly to wound sites. EXPAREL® is a long acting pain reliever.
- Trial name
- NCT02072135
- Testing
- Exparel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing elective arthroscopic shoulder surgery on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993798
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 10 sites in Austria, Germany and 3 more
- Volunteers
- 107 people
- Sponsor
- Durect
Pain, Postoperative, Cesarean Section Complications
Satisfaction Following Cesarean Section
Presently, the standard of care at the investigators' practice is that the discharging physician decides the type and amount of opioid medication to prescribe a patient following a cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section Complications, Postpartum Disorder, Opioid Use
- Trial name
- NCT03355248
- Testing
- Oxycodone Acetaminophen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ProMedica Health System
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Pain, Postoperative, Bariatric Surgery Candidate
A Study to Compare Two Techniques for Pain Control After Bariatric Surgery
The purpose of this study is to compare the postoperative pain and other clinical outcomes in patients who, during bariatric surgery, will be injected with a local anesthetic (Ropivacaine) through two different techniques.
- Trial name
- NCT04427059
- Testing
- Transversus Abdominis Plane (TAP) block, Port-Site Infiltration (PSI)
- Where
- Switzerland
- Volunteers
- 115 people
- Sponsor
- Fabio Garofalo
Thoracic Diseases
Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Thoracotomy
Thoracotomy surgery is the most painful of all surgical procedures. Inadequate postoperative pain control in these patients may cause serious morbidity related to pulmonary, cardiovascular and emotional systems.
- Trial name
- NCT04221880
- Testing
- Bupivacaine Hcl 0.25% Inj, Saline Solution for Block, Saline Solution intravenously
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Post Operative Pain
External Oblique Intercostal Plane Block for Patients Undergoing Upper Abdominal Surgeries
Ithe study will evaluate the analgesic efficacy of external oblique intercostal block for patients undergoing upper abdominal surgeries
- Trial name
- EOINB (NCT06514417)
- Testing
- US-guided external oblique intercostal block
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Menoufia University
Colon Cancer
the Effect of the Transversus Abdominis Plane (TAP) Block on the Minimal Laparotomy : a Randomized Controlled Trial
Transversus abdominis plane block (TAP block) is a new regional block for abdominal wall.It had been reported the effect of post-operative pain control in minor abdominal surgery, such as inguinal hernia repair and appendectomy.
- Trial name
- NCT01418391
- Testing
- Transversus Abdominis Plane block
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain, Postoperative, Shoulder Osteoarthritis
Effective Pain Management During Shoulder Replacement Surgery With EXPAREL
The purpose of this study is to examine the effectiveness of post-operative pain control of local infiltration (LIA) of EXPAREL administration to ropivacaine administered via continuous interscalene nerve block (CINB) for…
- Trial name
- NCT03474510
- Testing
- local infiltration of liposomal bupivacaine, continuous infusion of ropivacaine interscalene nerve block
- Where
- United States
- Sponsor
- TriHealth Inc.
Post-operative Analgesia, Early Mobility
Comparison of the Combination of Popliteal Sciatic and Femoral Block With the Combination of Ipack Adductor Canal Blocks
Comparison of the combination of popliteal sciatic and femoral block with the combination of ipack adductor canal blocks and mobilization and analgesia duration in elective knee surgeries
- Trial name
- kneesurgery (NCT06683313)
- Testing
- combination femoral nerve and popliteal sciatica block, combination adductor canal and IPACK block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Paravertebral Peripheral Nerve Block, Acute Pain Management
Ultrasound-Assisted Paravertebral Block v. Traditional Paravertebral Block For Pain Control
The overall purpose of this research study is to compare the effectiveness of ultrasound assisted paravertebral block placement versus traditional "blind" technique for postoperative analgesia following thoracotomy or visually…
- Trial name
- NCT01949480
- Testing
- Thoracotomy, Video-Assisted Thoracoscopic Surgery (VATS)
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh
Spinal Surgery, Post-operative Care
Perioperative Rectal Methadone in Spine Surgery
Patients undergoing spinal surgery require pain control medication after their surgery. Investigators have successfully used intravenous Methadone to manage pain after surgery.
- Conditions
- Spinal Surgery, Post-operative Care, Post-operative Pain Management
- Trial name
- PROMISE (NCT06843174)
- Testing
- Rectal Methadone administer during spinal surgery
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
Postoperative Pain, Tonsillectomy
Sphenopalatine Ganglion Block for Pain Relief After Pediatric Adenotonsillectomy
The aim of this clinical trial is to discover whether sphenopalatine ganglion block (SPGB) reduces postoperative pain in children aged 2 to 13 years undergoing tonsil surgery (with or without adenoid removal).
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- SPARK (NCT07793617)
- Testing
- Sphenopalatine ganglion block (Ropivacaine)
- Volunteers
- 145 people
- Sponsor
- Vinícius C Quintão, MD, MSc, PhD
Surgical Wound, Post-Op Complication
CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery
Major abdominal surgery is associated with significant complications which may lead to morbidity and mortality. Pain experienced after surgery affects the recovery from surgery.
- Conditions
- Surgical Wound, Post-Op Complication, Opioid Use
- Trial name
- CLoWI (NCT04503720)
- Testing
- CLoWI, PCA
- Where
- 2 sites in Singapore
- Volunteers
- 52 people
- Sponsor
- JurongHealth
Postoperative Pain
Comparison of Regional Block, Caudal Block and Wound Infiltration in Inguinal Hernitomy
Background: Although Inguinal herniotomy in children is taken as a day care procedure, post-operative pain management still remain controversial in these cases and superiority of wound infiltration, caudal block or regional block…
- Trial name
- Painseverity (NCT06386250)
- Testing
- regional block, Caudal block, Epidural
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- King Edward Medical University
Post Operative Pain, Laparoscopic Sleeve Gastrectomy
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
This will be a prospective, obesity-registry based, single-blind randomized controlled trial with a 1:1 allocation ratio. Specific inclusion criteria are all patients eligible to undergo a Laparoscopic sleeve gastrectomy (LSG)…
- Conditions
- Post Operative Pain, Laparoscopic Sleeve Gastrectomy, Robotic Sleeve Gastrectomy, Obesity
- Trial name
- EARLY (NCT06425016)
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Robotic Sleeve Gastrectomy (RSG)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ricard Corcelles
Lung Diseases, Lung Cancers
Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients
This prospective, observational study included ASA class II-III patients aged 18-70 years who underwent elective unilateral lobectomy via a thoracotomy.
- Trial name
- NCT06964698
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
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