Clinical trials: Post-operative Pain Control
Gynecology
the Effect of Pre-sacral Nerve Block on Post-operative Pain Following Laparoscopic Hysterectomy
40 patients who are consenting to be recruited in the study and are fulfilling the eligibility criteria will be subjected to: Group A Before the removal of uterus and the closure of vaginal cuff, insertion of 6inch 22G needle 2…
- Trial name
- NCT05757011
- Testing
- pre-sacral nerve block (bupivacaine injection into both uterosacral ligaments at the end of laparoscopic hysterectomy.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Postoperative Pain, Kidney Calculi
Nephrostomy Tract Infiltration for Pain Control After PCNL
This prospective, randomized, controlled clinical trial aims to evaluate the effectiveness of nephrostomy tract local anesthetic infiltration for postoperative pain control in patients undergoing prone percutaneous…
- Trial name
- NCT07721571
- Testing
- Bupivacaine, Intravenous Tramadol and Paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Pain
The Effectiveness and Safety of Gabapentin for Post-operative Pain After Cesarean Section
The purpose of this study is to determine whether a single dose of gabapentin, given before cesarean section, will reduce pain in the initial 24 hours after surgery.
- Trial name
- NCT00573664
- Testing
- Gabapentin, lactose
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia
Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee Arthroscopy
A randomized double-blinded clinical trial was carried out on 40 patients undergoing knee arthroscopy. Patients were divided randomly into two equal groups.
- Trial name
- NCT04790292
- Testing
- group M, group MD
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Pain, Postoperative
A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain
the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus US guided QL catheters
- Trial name
- NCT04368364
- Testing
- Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Sacral Erector Spinae Plane Block, Caudal Block
Sacral Erector Spinae Plane Block Versus Caudal Block in Penile Surgeries in Pediatrics
The study will be conducted to compare the efficacy of ultrasound guided Sacral Erector Spinae Plane Block to caudal block on pain management in penile surgeries in pediatrics.
- Conditions
- Sacral Erector Spinae Plane Block, Caudal Block, Penile Surgeries, Pediatrics
- Trial name
- NCT06235944
- Testing
- Caudal block, Sacral erector spinae block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Post Operative Pain
Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy
The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive U S guided external oblique intercostal block after induction.
- Trial name
- EOINBvsESB (NCT06048744)
- Testing
- external oblique intercostal block, Erector Spine block
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Menoufia University
Osteoarthritis, Knee
Postoperative Pain Control Results Using Periarticular Versus Intra-capsular Injection of Bupivacaine Liposome Injectable Suspension in Total Knee Arthroplasty
The purpose of this study is to determine quantitative and qualitative differences in post-operative pain relief for patients undergoing primary total knee arthroplasty (TKA) who receive administration of a newly approved, long…
- Trial name
- NCT02166632
- Testing
- Intracapsular Injection, Periarticular Injection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Broward Health
Post Operative Analgesia, Dexmedetomidine
Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone
Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding…
- Conditions
- Post Operative Analgesia, Dexmedetomidine, TAP Block
- Trial name
- NCT07508202
- Testing
- Dexmedetomidine, Dexamethasone
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Postoperative Pain
TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain
In this randomized, controlled, double-blinded trial we plan to evaluate post-operative pain relief after laparoscopic-assisted Transversus Abdominis Plane (TAP) block using liposomal bupivacaine plus bupivacaine versus…
- Trial name
- LATAP (NCT02400645)
- Testing
- Pre-incisional wound infiltration, Laparoscope to place TAP block with liposomal bupivacaine, Liposomal bupivacaine
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Chronic Shoulder Pain
Exparel for Total Shoulder Pain
Total shoulder surgery (arthroplasty) is a widely successful method of treating shoulder arthritis. Although the goal of the procedure is pain relief, post-operative pain is unavoidable.
- Trial name
- ETSP (NCT03739021)
- Testing
- Exparel, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Total Knee Arthroplasty, Post Operative Analgesia
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
Many methods of pain relief have been implemented in an attempt to provide safe and effective analgesia for patients following total knee arthroplasty.
- Trial name
- NCT00677261
- Testing
- Sciatic Nerve Block, Posterior capsule infiltration with local anesthetic
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hemorrhoids
Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy
Over the past decade, continuous wound infiltration systems have been introduced to treat a variety of post-surgical pain. These systems, commonly referred to pain pumps by patients, possess a catheter(s) attached to a reservoir…
- Trial name
- NCT01099605
- Testing
- placement of a continuous infusion pump, continuous infusion pump of bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Tonsillitis, Post-operative Nausea and Vomiting (PONV)
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham.
- Conditions
- Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction
- Trial name
- NCT06326983
- Testing
- Dexmedetomidine, Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston Children's Hospital
Tibial Plateau Fracture, Pain, Postoperative
Duloxetine Tibial Plateau
The purpose of this study is to determine if Duloxetine provides effective pain management for adult patients (18 or older) undergoing tibial plateau surgery.
- Trial name
- NCT04639011
- Testing
- Duloxetine, Standard of care (SOC) for tibial plateau surgery
- Where
- 2 sites in United States
- Sponsor
- Boston Medical Center
Hip Fractures, Post Operative Pain
Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block
The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries
- Trial name
- NCT06294665
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Oocyte Retrieival and Post Operative Pain Control, Acupuncture
ACU-TENS on Pain and Stress Reduction Before and During TUGOR
Objectives: To demonstrate the use of acupuncture-type transcutaneous electrical nerve stimulation (acu-TENS) during transvaginal ultrasound-guided oocyte retrieval (TUGOR) will reduce 50% of the intensity of pain experienced by…
- Trial name
- NCT06910540
- Testing
- Acu-TENS
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Chinese University of Hong Kong
Physiological Effect of Drugs, Morphine
Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
The purpose of this study is to show that the effect of 3% 2-chloroprocaine prior to epidural morphine administration will be not inferior to the effect of epidural 2% lidocaine with 1:200,000 epinephrine on total opioid use for…
- Conditions
- Physiological Effect of Drugs, Morphine, Analgesics, Analgesics, Opioid
- Trial name
- NCT04369950
- Testing
- 2% lidocaine with 1:200,000 epinephrine and epidural morphine, 3% 2-chloroprocaine and epidural morphine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain
Comparison of Surgical Rectus Sheath Block and Intrathecal Morphine
Pain is the main obstacle in delaying postoperative recovery and leads to prolonged hospital stay. Administration of intrathecal morphine during spinal anaesthesia can provide effective pain control.
- Trial name
- NCT02790099
- Testing
- Bupivacaine, Morphine
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- Queen Mary Hospital, Hong Kong
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