Clinical trials: Post-operative Pain Control
Pain, Postoperative
A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain
the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus US guided QL catheters
- Trial name
- NCT04368364
- Testing
- Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Wounds Injuries, Anesthesia, Local
Single-centre Study to Investigate Safety and Efficacy of Tri-Solfen in Wound Debridement
This is a Phase IIa open, randomised, single and parallel group, therapy controlled, single centre study, which has been divided into 3 sequential phases, which are designed to study respectively, (a) the time taken to achieve…
- Trial name
- NCT03865147
- Testing
- Tri-Solfen Gel (Lidocaine HCl, Bupivacaine HCl, Adrenaline Acid Tartrate /Cetrimide), EMLA cream, Post Operative Analgesia (Paracetamol, Ibuprofen)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Medical Ethics UK Ltd
Vasectomy, NSAIDs
Post-Vasectomy Pain Study
This is a prospective four-armed unblinded randomized controlled trial to assess four different potential post-operative treatment options for men who undergo a vasectomy.
- Conditions
- Vasectomy, NSAIDs, Post-operative Care
- Trial name
- NCT07824258
- Testing
- Acetaminophen, ibuprofen, oxycodone
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Bilateral Superficial Cervical Block
Ultrasound Guided Bilateral Superficial Cervical Block for Post-operative Pain Therapy in Thyroid Surgery
Ultrasound Guided Bilateral Superficial Cervical Block for Postoperative Pain Therapy in Thyroid Surgery
- Trial name
- NCT03109691
- Testing
- bupivacaine, Dexamethasone, ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Analgesia
Analgesic Techniques for Robotic Prostatectomy Procedures
Robot-assisted radical prostatectomy and robot-assisted simple prostatectomy are minimally invasive procedures associated with reduced postoperative pain compared to open surgery.
- Trial name
- PROPAIN (NCT07483840)
- Testing
- Thoracic Erector Spinae Plane Block (ESPB-T), Rectus Sheath Block (RSB), Low-dose Spinal Analgesia (SA)
- Where
- Italy
- Volunteers
- 147 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Kidney Transplant Recipient, Kidney Transplant Donor
Investigation of the Effects of Quadratus Lumborum Block Applied to Patients in Kidney Transplant Surgery
This study aims to determine the most effective and long-lasting pain relief method for post-operative analgesia in kidney donor and recipient patients in kidney transplantation programme with the least invasive and least drug…
- Trial name
- NCT06011850
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Post Operative Pain, Shoulder Pain
The Effect of Postoperative Modified Trendelenburg Position to Decrease Shoulder Pain After Laparoscopic Hysterectomy: A Randomized Controlled Trial
Laparoscopic surgery is commonly used procedure in diagnostic and treatment including Hysterectomy. Post laparoscopic shoulder pain is common side effect mostly occur after surgery.
- Conditions
- Post Operative Pain, Shoulder Pain, Gynecologic Disease
- Trial name
- NCT05428982
- Testing
- Postoperative Modified Trendelenburg position
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Postoperative Pain, Postoperative Nausea and Vomiting
Effects of Methylprednisolone After Total Knee Arthroplasty
The purpose of the study is to compare the effects of pre-operative methylprednisolone (125mg iv) versus placebo on postoperative outcome after knee arthroplasty.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Sleeping Quality, Fatigue
- Trial name
- NCT00968578
- Testing
- Methylprednisolone
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Post-operative Pain, Thoracic Epidural
Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
To find out if there is a benefit from adding dexmedetomidine to epidural bupivacaine as regards: Intra and postoperative opioid consumption Pain score (numerical rating scale) Hemodynamic stability, Patient satisfaction.
- Conditions
- Post-operative Pain, Thoracic Epidural, Thoracotomy Surgery
- Trial name
- adjuvants (NCT06489574)
- Testing
- thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery, thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Pain
IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative pain management after C-section is an important topic as the number of elective c-sections increases each year. Pain is managed either by giving opioids or by using non-opioids.
- Trial name
- NCT02069184
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Montefiore Medical Center
Total Knee Replacement
Femoral Block With or Without Ropivacaine for Analgesia After Total Knee Replacement (TKR)
Total knee replacement is a painful procedure. Many solutions have been proposed to diminish the post-operative doses of narcotics, including nerve blocks.
- Trial name
- TKR (NCT00910013)
- Testing
- Ropivacaine
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Hopital de l'Enfant-Jesus
Post-operative Pain
To Evaluate the Effect of Wound Infiltration With Bupivacaine for Post-operative Pain Relief After Laparoscopic Cholecystectomy
To evaluate the effect of wound infiltration with 0.25% Bupivacaine in laparoscopic cholecystectomy in terms of pain severity, patient satisfaction level, quality of life, hospital stay and return to job and normal activities.
- Trial name
- NCT03958513
- Testing
- Bupivacaine, 0.9% normal saline
- Where
- Bangladesh
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Ovarian Cancer, Post Operative Pain
Intraperitoneal Lidocaine in Ovarian Cancer Surgery
The main objective of this trial is to improve the postoperative analgesia effect and prognosis of patients with ovarian cancer after laparotomy surgery.
- Trial name
- NCT05450055
- Testing
- intraperitoneal lidocaine analgesic or normal saline as control
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Total Knee Arthroplasty
Single-injection Adductor Canal Block for Total Knee Arthroplasty Under Spinal Anesthesia
This study evaluates the effect of the single-injection adductor canal block in patients receiving total knee arthroplasty under spinal anesthesia.
- Trial name
- NCT04400708
- Testing
- adductor canal block, control group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pain
Is Paracetamol an Effective Treatment for Chronic Moderate Pain in the Newborn After Operative Vaginal Delivery?
There are many reasons for using a vacuum apparatus or forceps to assist in delivering a baby. The traction and pressure on the baby's head due to the vacuum apparatus or forceps may cause pain and discomfort for some time after…
- Trial name
- NCT00488540
- Testing
- Paracetamol
- Where
- 3 sites in Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Complication of Anesthesia
Assessing Peripheral Nerve Block Scoring Systems for Intra-Operative and Post-Operative Analgesia
The purpose of this study is to determine if Peripheral Nerve Block scoring systems are effective in predicting the achievement of intra-operative anaesthesia and post-operative analgesia.
- Trial name
- NCT02041806
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- The Adelaide and Meath Hospital
Post-Operative Pain
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
The study is intended to show that the Sufentanil NanoTab PCA System is as effective as morphine intravenous patient-controlled analgesia (IV PCA) for treating pain after surgery.
- Trial name
- NCT01539538
- Testing
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Where
- 16 sites in United States
- Volunteers
- 357 people
- Sponsor
- Talphera, Inc
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