Clinical trials: Post-operative Pain Control
Carious Exposure of Pulp
Comparison of Postoperative Pain After Pulpotomy Performed With Versus Without Dental Operating Microscope in Carious Mature Permanent Teeth
The goal of this [randomized clinical trials] is to investigate the effect of using dental operating microscope incorperated in full pulpotomy procedure in mature carious posterior teeth.
- Trial name
- NCT07373977
- Testing
- Using dental operating microscope
- Volunteers
- 82 people
- Sponsor
- Chulalongkorn University
Pain, Postoperative
Evaluation of Preoperative N1539 in Total Knee Arthroplasty
The primary objective of this study is to assess the effect of preoperative administration of N1539 on opioid consumption in subjects undergoing open unilateral total knee arthroplasty compared to placebo.
- Trial name
- NCT03434275
- Testing
- N1539
- Where
- 6 sites in United States
- Volunteers
- 194 people
- Sponsor
- Baudax Bio
Quadratus Lumborum Block
Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy
To compare the postoperative analgesic effect of two ultrasound guided approaches of quadratus lumborum block (QLB) (anterior and intramuscular) for radical cystectomy.
- Trial name
- NCT05089994
- Testing
- US guided injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain
Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery
Pain following abdominal surgery is managed with the use of thoracic epidural analgesia (TEA) where the epidural is inserted in the spine at the level of scapula The risks due to TEA include difficulty with insertion, failure in…
- Trial name
- NCT01735851
- Testing
- Thoracic epidural analgesia, Bilateral Paravertebral block
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Patient-Controlled Analgesia
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery.
- Trial name
- POPCORN (NCT06186141)
- Testing
- Morphine, Oxycodone
- Where
- Australia
- Volunteers
- 690 people
- Sponsor
- Murdoch Childrens Research Institute
Post Operative Pain
Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain
Caesarean section is a common method of delivery in obstetrics. With the recent increase in the rate of this procedure, it is wise to understand and implement the optimal surgical technique.
- Trial name
- NCT03513237
- Testing
- Cervical dilation
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Effect of Bilateral Erector Spinae Plan Block in Colorectal Surgery
In this study, it was aimed to evaluate the effects erector spina plane block (ESPB) on postoperative opioid consumption in the first 24 hours and pain scores after colorectal surgery.
- Trial name
- NCT05256953
- Testing
- Erector spina plane block + general anesthesia, Only general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Pain, Postoperative
Caffeine Study for Pain Control Following Total Joint Replacement
A prospective, double blinded, single center, randomized controlled study to evaluate the efficacy of caffeine in combination with acetyl salicylic acid (ASA) in the management of postoperative pain in patients undergoing total…
- Trial name
- NCT04280263
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Rothman Institute Orthopaedics
Postoperative Pain, Medication Side Effects
Pain Control After Minimally Invasive Coronary Artery Bypass Grafting
The purpose of this study is to compare postoperative pain control after minimally invasive coronary artery bypass grafting for patients who receive an intercostal block (an anesthetic medicine injected in an area under the ribs)…
- Conditions
- Postoperative Pain, Medication Side Effects, Narcotic Requirement
- Trial name
- NCT01770236
- Testing
- IV acetaminophen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Postoperative Pain, Surgery
Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control
To determine if Exparel (Liposomal Bupivacaine, an FDA approved drug) use in ultrasound guided Transversus Abdominis Plane (TAP) blocks may reduce opioid requirement use postoperatively, reduce pain scores postoperatively, reduce…
- Conditions
- Postoperative Pain, Surgery, Anesthesia, Local
- Trial name
- NCT03878888
- Testing
- Exparel 266 MG Per 20 ML Injection
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Post Operative Pain, Anesthesia
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
Comparison of post-operative pain after total shoulder surgery. The Principle Investigator will be comparing Exparel single shot block to Interscalene catheter
- Conditions
- Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
- Trial name
- NCT05868330
- Testing
- Interscalene Catheter, Exparel Single Shot Interscalene Block
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
Pain, Postoperative
US-guided Ilioinguinal Blocks Versus Local Infiltration
Injection of local anesthetic drugs is an effective way to freeze (block) nerves to achieve loss of sensation during surgery and satisfactory pain control afterwards.
- Trial name
- NCT01871181
- Testing
- Ilioinguinal block, Local infiltration
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Anesthesia
Intraperitoneal Bupivacaine With Magnesium or Nalbuphine for Postoperative Pain Control in Laparoscopic Hysterectomy
The purpose of this study is to compare between the addition of Mg sulphate or Nalbuphine to intraperitoneal bupivacaine installation in laparoscopic hysterectomy for postoperative pain control and their relative adverse effects.
- Trial name
- NCT03393572
- Testing
- Bupivacaine 0.25%, Magnesium sulphate., nalbuphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Postoperative Pain, Preoperative Anxiety
Aromatherapy and Its Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience
Aromatherapy's Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience Introduction: Surgery often results in increased levels of anxiety and postoperative pain.
- Conditions
- Postoperative Pain, Preoperative Anxiety, Patient Experience
- Trial name
- NCT07771205
- Testing
- Aromatherapy, Unscented Pod
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Ankle Arthritis, Ankle Arthropathy
Peripheral Nerve Block Compared to Intra-articular Injection for TAA Post-operative Pain
Ankle arthritis is associated with debilitating pain and chronic disability. For the treatment of severe ankle arthritis, total ankle arthroplasty (TAA) is one treatment option.
- Trial name
- NCT03674905
- Testing
- Intra-articular injection, Peripheral nerve block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Slocum Research & Education Foundation
Fistula in Ano
Post-op Pain After Fistula Laser Closure or Ligation of the Intersphincteric Tract for Anal Fistula
This is a prospective, double-blinded randomised controlled trial conducted at two tertiary hospitals by a credentialed colorectal surgeon.
- Trial name
- LASERLIFT (NCT06212739)
- Testing
- Laser, LIFT
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- University of Malaya
Post Operative Analgesia, Bradycardia
Comparative Analysis Of Dexmedetomidine And Dexamethasone As An Adjuvant To 0.5%Ropivacaine On Onset Of Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries
To compare the efficacy of dexmedetomidine and dexamethasone as an adjuvant to 0.5%ropivacaine on onset of ultrasound guided supraclavicular brachial plexus block in patients undergoing upper limb surgeries.
- Conditions
- Post Operative Analgesia, Bradycardia, Hypotension, Upper Limb Surgeries
- Trial name
- NCT07290595
- Testing
- Ropivacaine + Dexmedetomidine, Ropivacaine + dexamethasone
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Orthopaedic Related Pain (Musculoskeletal Pain), Opioid
Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients
This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioids) in patients undergoing…
- Conditions
- Orthopaedic Related Pain (Musculoskeletal Pain), Opioid, Pain, Pilot Study
- Trial name
- NCT07265557
- Testing
- Discharge pain medication prescription
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Post Operative Analgesia, Dexmedetomidine
Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone
Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding…
- Conditions
- Post Operative Analgesia, Dexmedetomidine, TAP Block
- Trial name
- NCT07508202
- Testing
- Dexmedetomidine, Dexamethasone
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
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