Clinical trials: Post-operative Pain Control
Ophthalmic Surgery, Postoperative Pain Management
Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery
The goal of this clinical trial is to learn if Anrikefon works as well as nalbuphine to control postoperative pain in adults undergoing ophthalmic surgery under general anesthesia.
- Conditions
- Ophthalmic Surgery, Postoperative Pain Management, Opioid Analgesia
- Trial name
- NCT07269106
- Testing
- Anrikefon, Nalbuphine
- Where
- 3 sites in China
- Volunteers
- 204 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Post Operative Analgesia
The Ultrasound Guided Pericapsular Nerve Group and Anterior Quadratus Lumborum Blocks in Hip Replacement Surgeries
The investigators hypothesis that PENG block will produce effective opioid sparing analgesia with enhanced motor recovery more than AQLB in elderly patients undergoing total hip replacement surgeries
- Trial name
- NCT06679764
- Testing
- Anterior quadratus lumborum block technique (AQLB), Pericapsular Nerve Group (PENG) block, Control Group
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University
Pain, Vertigo
Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy
The investigators hypothesize that the use of tramadol will reduce pain and analgesic consumption after arthroscopic shoulder surgery.
- Conditions
- Pain, Vertigo, Nausea, Pruritus
- Trial name
- NCT02247648
- Testing
- tramadol
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colorectal Surgery, Pain, Postoperative
Intrathecal Opioids for Colorectal Resection
This research study is being done to determine the optimal dose of spinal morphine and hydromorphone in patients undergoing minimally-invasive (i.e., surgery performed through small entry sites and using cameras) colorectal…
- Conditions
- Colorectal Surgery, Pain, Postoperative, Analgesic, Opioid
- Trial name
- NCT04752033
- Testing
- Morphine, Hydromorphone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Hip Fracture, Analgesia Post Fracture
PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture
Pericapsular Nerve Group Block (PENG) is an effective regional anaesthesia modality in providing analgesia following neck of femur fracture.
- Trial name
- NCT07046052
- Testing
- continuous infusion of levobupivacaine, Programmed Intermittent Bolus of Levobupivacaine
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- University College Cork
Pain, Postoperative
Effectiveness of Port Site Bupivacaine Injection in Postoperative Pain Reduction After Lap. Chole
To determine the effectiveness of port site bupivacaine infiltration in postoperative pain reduction after laparoscopic cholecystectomy.
- Trial name
- NCT05264805
- Testing
- 0.25% Bupivacaine
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Necrotic Pulp
Evaluation of Pain Relief and Bacterial Reduction After Using Calcium Hydroxide With Mesoporous Silica Nanoparticles as an Intracanal Medicament in Necrotic Mandibular Molars: A Randomized Controlled Clinical Trial
This study compares how well different root canal medications reduce pain and bacteria after treatment of lower molar teeth with necrotic pulp.
- Trial name
- NCT07327996
- Testing
- Calcium Hydroxide Intracanal medication, mesoporous silica nanoparticles paste, Calcium Hydroxide + mesoporous silica nanoparticles
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Third Molar Surgery, Post Operative Analgesia
'Propolis Versus Chlorhexidine Gluconate on Wound Healing After Third Molar Surgery: a Randomized Controlled Trial'
The goal of this study is to examine the effects of propolis gargle on wound healing following third molar surgery and to compare it with chlorhexidine gluconate.
- Trial name
- NCT07364253
- Testing
- Third molar Surgery with propolis gargle, Third molar surgery with chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Rotator Cuff Tears, Shoulder Pain
Effect of Kinesio Taping After Rotator Cuff Surgery
This prospective randomized controlled trial evaluated whether adding Kinesio Taping (KT) to a standardized postoperative rehabilitation program improves early clinical recovery after arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Shoulder Pain, Post Operative Pain
- Trial name
- RCR-KT (NCT07375927)
- Testing
- Kinesio Taping, Standard Postoperative Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Olcay Yavuz
Postoperative Analgesia
Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.
The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, compared to ropivacaine alone…
- Trial name
- NCT03809442
- Testing
- Ropivacaine + Ketamine, Ropivacaine + Tramadol, Ropivacaine + Midazolam
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Aga Khan University
Post Operative Analgesia, Total Knee Arthroplasty
Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques
Postoperative pain following total knee arthroplasty (TKA) is a significant clinical problem that delays early mobilization, reduces patient satisfaction, and increases analgesic requirements.
- Trial name
- NCT07242170
- Testing
- Adductor canal block, BiFeS Block (Biceps Femoris Short Head Block), IPACK block
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Erzincan University
Alcoholic Patient, Carcinological Surgery ORL
Systemic Ketamine for the Improvement of Post-Operative Analgesia at the Alcohol-Dependent Patient
The principal objective is to evaluate the analgesic effectiveness of the systemic ketamine on the control of the pain (average consumption of morphine at 48 hours) at the alcool-dependent patient, in carcinological surgery ORL.
- Trial name
- NCT00329394
- Testing
- ketamine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug)
Pain Control After Lumbar Spine Fusion
The purpose of this randomized controlled trial is to determine if patients who receive non-steroidal anti-inflammatory medications (NSAIDs) following elective lumbar spinal fusion have increased rates of symptomatic nonunion…
- Conditions
- Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug), Postoperative Pain
- Trial name
- NCT06484192
- Testing
- Naproxen 500 Mg, Ketorolac, OxyCODONE 5 mg Oral Tablet
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Post Operative Pain
Sacral Erector Spinae Block for Pilonidal Sinus Surgery
The incidence of pilonidal sinus disease (PD) is estimated to be around 26/100,000 individuals mostly men.PD can cause the development of abscess or a draining sinus tract and that may lead to a loss of productive power and…
- Trial name
- NCT06577064
- Testing
- Sacral erector spinae plane block
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Post Operative Pain, Mechanisms of Analgesia
Pericapsular Nerve Group Block: An Imaging Study for Determination of the Spread of the Injectate Using 3-D CT Scan
Over the last 20 years, different interventional regional analgesia techniques have been proposed to treat pain after hip surgeries.
- Trial name
- NCT06062134
- Testing
- Pericapsular nerve group block, 18 mL ropivacaine 0.5% + 2 mL radiopaque contrast
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Philippe Gauthier
Surgical Blood Loss, Postoperative Pain
PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.
This randomized controlled trial compares periarticular vasoconstrictor infiltration (PVI) versus erector spinae plane block (ESP) to reduce bleeding and postoperative pain in adults undergoing lumbar fusion surgery (up to 3…
- Conditions
- Surgical Blood Loss, Postoperative Pain, Lumbar Spinal Fusion Surgery
- Trial name
- NCT07550114
- Testing
- Periarticular vasoconstrictor infiltration (PVI), Erector Spinae Block (ESP)
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pain, Postoperative Pain
Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt…
- Trial name
- NCT04835116
- Testing
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg., paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Osteoarthritis, Knee
Postoperative Pain Control Results Using Periarticular Versus Intra-capsular Injection of Bupivacaine Liposome Injectable Suspension in Total Knee Arthroplasty
The purpose of this study is to determine quantitative and qualitative differences in post-operative pain relief for patients undergoing primary total knee arthroplasty (TKA) who receive administration of a newly approved, long…
- Trial name
- NCT02166632
- Testing
- Intracapsular Injection, Periarticular Injection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Broward Health
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction
The goal of this clinical trial is to learn whether taking oral tranexamic acid (TXA) for one week after anterior cruciate ligament (ACL) reconstruction improves recovery in adolescents and young adults aged 14 to 25 years.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Trial name
- NCT07880743
- Testing
- Tranexamic Acid
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dave Bernholt
Post Operative Pain
Pectointercostal Block for Postoperative Pain Management After Sternotomy
This randomized, controlled study is designed to assess the quality of analgesia provided by ultrasound-guided bilateral pectointercostal facial block in children undergoing cardiac surgery via midline sternotomy.
- Trial name
- NCT05552417
- Testing
- Pectointercostal facial plan block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
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