Clinical trials: Post-operative Pain Control
Choroidal Melanoma, Melanoma
Pain Relief - Tramadol Versus Ibuprofen
The purpose of this study is to assess post operative pain following the insertion of radioactive plaque for choroidal melanoma in patients after receiving either ibuprofen or tramadol.
- Conditions
- Choroidal Melanoma, Melanoma, Eye Neoplasms
- Trial name
- NCT00111046
- Testing
- Ibuprofen, Tramadol
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Liverpool University Hospital
Total Knee Arthroplasty
Can Dexmedetomidine For Procedural Sedation In Knee Arthroplasty Reduce Postoperative Pain? A Randomized Control Study
Dexmedetomidine has been often used for procedural sedation. It has also has been shown to have a pain sparing effect. Therefore the investigators propose that if Dexmedetomidine is used for sedation in total knee replacements…
- Trial name
- NCT02026141
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Cystectomy
Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy
The purpose of this study is to compare the difference between four different pain control methods in patients who will be having a cystectomy surgery (surgical removal of the bladder).
- Trial name
- NCT04300231
- Testing
- epidural bupivacaine 0.05%, Liposomal bupivacaine, bupivacaine 0.125%
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Indiana University
Acute Post Operative Pain, Laparotomy
PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose
Pain control after surgery is a crucial component of postoperative recovery. Thus, in open abdominal surgery, the use of TEA (Thoracic epidural analgesia) has become a gold standard.
- Conditions
- Acute Post Operative Pain, Laparotomy, Epidural Analgesia
- Trial name
- PIBDOSE (NCT05534945)
- Testing
- Programmed intermittent epidural bolus 5 ml, Programmed intermittent epidural bolus 6 ml, Programmed intermittent epidural bolus 7 ml
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Low-lying Unilateral Palpable Undescended Testis
Expertise-Based Randomized Controlled Trial of Scrotal Versus Inguinal Orchidopexy on Post-operative Pain
Undescended Testis is the most common congenital abnormality of the genitalia in boys and it is commonly managed by surgical intervention.
- Trial name
- EXPRESSO (NCT02158780)
- Testing
- Scrotal Orchidopexy, Inguinal Orchidopexy
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- McMaster University
Spine Surgery
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
This study will investigate whether a combination of three anesthetic medications will reduce intraoperative and postoperative pain in patients undergoing complex spine surgery, and whether it will reduce the use of opioid pain…
- Trial name
- NCT07365800
- Testing
- Methadone-dexmedetomidine-ketamine combination
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- University of Missouri-Columbia
Inguinal Hernia, Postoperative Pain
Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal hernia repair is one of the most frequently performed operations in young men. Persistent pain after inguinal surgery represents a significant cause of disability, occurring in between 15%-35% of cases.
- Trial name
- NCT00825344
- Testing
- Etanercept, Saline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Knee Osteoarthritis
Efficacy of Different Doses of Pregabalin as a Multimodal Analgesic Agent in Postoperative Pain Control After Total Knee Arthroplasty
The purpose of this study is to compare the efficacy of 75 mg of Pregabalin and 150 mg of Pregabalin in postoperative pain control after TKA.
- Trial name
- NCT05447364
- Testing
- Pregabalin 75mg, Pregabalin 150mg
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Thammasat University
Post-operative Pain, Acute
To Compare the Skin Incision Made by the Electrocautery and Scalpel in Inguinal Hernia Repair
The Groin hernia repair is a commonly performed general surgery procedure in both adults and children with inguinal hernias constituting more than 95% of all groin hernia repairs.
- Trial name
- NCT05666973
- Testing
- Open Mesh Hernioplasty
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Analgesia, Surgery
High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.
This study aims to compare the efficacy and quality of pain relief provided by the high-dose serratus anterior plane (SAP) block with the standard SAP block in preventing and treating acute postoperative pain after total…
- Conditions
- Analgesia, Surgery, Cardiac Disease, Post Operative Pain
- Trial name
- NCT06205875
- Testing
- High dose serratus anterior plane block (2.4 mg/kg patient ideal body weight), Low dose serratus anterior plane block (1.2mg/kg patient ideal body weight), PCIA with morphine
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Post Operative Dental Pain
A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain
The study is designed to assess the efficacy and tolerability of diclofenac potassium soft gelatin capsules compared with ibuprofen tablets in patients with moderate to severe postoperative dental pain.
- Trial name
- NCT02476422
- Testing
- Diclofenac potassium, Ibuprofen
- Where
- United States
- Volunteers
- 328 people
- Sponsor
- Novartis Pharmaceuticals
Post-operative Pain Control
Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone
Photorefractive keratectomy (PRK) is a refractive error correction procedure that helps eliminate or reduce the dependence on corrective lenses. An important aspect of PRK is post-operative pain management.
- Trial name
- NCT04399122
- Testing
- acetaminophen/codeine vs acetaminophen/oxycodone
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Postoperative Pain.
The Effects of Peri-operative Pregabalin Administration on Post-operative Analgesia in Patients Undergoing Coronary Bypass Grafting
We hypothesize that the perioperative administration of pregabalin will significantly decrease pain scores and post-operative opioid requirements for patients undergoing coronary artery bypass grafting, and reduces the incidence…
- Trial name
- NCT00623285
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Arthroplasty, Replacement, Knee, Pain, Postoperative
Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study
The objective of this study is to see how pain management and its outcomes are effected when pharmacogenomic testing is used to determine patient specific pain medication and dosing.
- Trial name
- NCT02711592
- Testing
- Genetic Panel for Analgesics
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- TriHealth Inc.
Post Operative Pain
Effects of Adding Dexamethasone Plus Ketamine to Bupivacine in Serrtatus Plane Block
This randomized, double-blind trial included 60 female patients undergoing modified radical mastectomy. The study carried out at National Cancer Institute, cairo university after approval of the local ethical committee.
- Trial name
- NCT05775393
- Testing
- Serratus anterior plane block for MRM
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain
Erector Spinae Plane Block for Postoperative Pain Control in Hip Replacement Surgeries
ESP block advantages include its simplicity, easy identifiable ultrasonographic landmarks and low risk for serious complications as injection is into tissue plane that is distant from pleura, major blood vessels and discrete…
- Trial name
- NCT04003909
- Testing
- ultrasound-guided Erector spinae plane block, subarachonoid block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Bassant M. Abdelhamid
Pain, Postoperative, Pain, Acute
Nurse Initiated Acupressure for Pain Management
The purpose of pilot study is to test the feasibility of nurse initiated post-operative bilateral auricular acupressure as an adjunct to medication for post-operative pain management.
- Trial name
- NCT04044716
- Testing
- Auricular acupressure, Standard of care pain management
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Wake Forest University Health Sciences
Post Operative Pain Control
Evaluation of the Role of Genicular Nerve Block When Combined With Adductor Canal Block for Pain Control Following Knee Arthroscopy
The intervention tests the efficacy of Genicular nerve block when combined with Adductor canal block in comparison with Adductor canal block alone to control post operative pain in knee arthroscopy
- Trial name
- NCT06951204
- Testing
- Adductor Canal Block (ACB) Only, Adductor canal block (ACB) combined with Genicular nerve block (GNB)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Cardiac Surgery, Post-operative Pain
Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy
Currently, the management of pain after cardiac surgery is based on the concept of multimodal analgesia: Combined use of non-opioid analgesics associated with morphine intravenous analgesia by a system controlled by the patient…
- Trial name
- LoDoNSAID (NCT02180087)
- Testing
- Ketoprofen
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
The purpose of this study is to compare the level of pain control in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs) to those receiving opioids in the postoperative period after endoscopic sinus surgery (ESS)…
- Trial name
- NCT03605914
- Testing
- diclofenac, Norco
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
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