Clinical trials: Post-operative Pain Control
Postoperative Analgesia, Pain Management
Comparison of Intrathecal Morphine and Rectus Sheath Block for Postoperative Pain Management After Lower Abdominal Surgery With Midline Incision
This study aims to evaluate the efficacy of intrathecal morphine and rectus sheath block compared with standard postoperative analgesia for pain management in patients undergoing lower abdominal surgery with a midline incision.
- Trial name
- NCT07489872
- Testing
- Intrathecal Morphine, Rectus Sheath Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Postoperative Pain
Intravenous Acetaminophen in Craniotomy
The purpose of this study is to assess the use of intravenous Acetaminophen (OFIRMEV) as an effective adjunct therapeutic agent in patients undergoing craniotomy.
- Trial name
- NCT01598701
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain, Gynecologic Disease
Additive Effect of Intravenous Acetaminophen on Postoperative Pain Control
This study aimed to evaluate the additive effect of acetaminophen on postoperative pain control in patients receiving nefopam and fentanyl-based patient-controlled analgesia.
- Trial name
- NCT03644147
- Testing
- Acetaminophen
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Post Operative Analgesia
Comparison of Efficacy of Bupivacaine Alone vs. Bupivacaine-Tramadol in Lower Limb Surgery
This randomized controlled trial aims to compare the effectiveness of bupivacaine alone versus bupivacaine combined with tramadol for postoperative analgesia in patients undergoing lower limb surgeries under spinal anesthesia.
- Trial name
- BUP-TRA-PAIN (NCT07827352)
- Testing
- Bupivacain only, bupivacain-tramadol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Farooq Hospital / Akhtar Saeed Medical college Rawalpindi
Hallux Valgus
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
The purpose of this study is to evaluate the analgesic efficacy and safety of tapentadol immediate-release (IR [CG5503]) for use in the relief of moderate to severe acute pain, compared with placebo, in adult Taiwanese patients…
- Trial name
- NCT01813890
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Janssen-Cilag International NV
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
Postoperative Pain
Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery
The goal of this study is to compare whether oral or intravenous acetaminophen works better for pain control in patients undergoing lumbar spine fusion surgery
- Trial name
- NCT07203079
- Testing
- Acetaminophen Oral Tablet, Acetaminophen infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Stanford University
Post-operational Pain
A Randomized, Double Blind, Placebo-controlled Study to Assess the the Preemptive Benefit of Etoricoxib in Patients Receiving Anterior Cruciate Ligament Reconstruction
Post surgical pain associated with ligament reconstruction may persist for few days after the surgical procedure. Arcoxia is a new anti-inflammatory and analgesic drug that alleviate pain through oral administration.
- Trial name
- NCT00554346
- Testing
- Arcoxia(etoricoxib 90 mg/tablet)
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan University Hospital
Post Operative Pain, Pain, Acute
Post-thoracotomy Pain Management With Active External Warming and Ice Application
The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption.
- Conditions
- Post Operative Pain, Pain, Acute, Thoracic Injury
- Trial name
- NCT05299788
- Testing
- Active external warming, Ice application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Post-operative Pain
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative Outcomes
Primary: To compare the post-operative pain in patients with neck extension and without neck extension. Secondary: To determine the benefit of neck exposure and peri-operative complications, which include duration of operation…
- Trial name
- NCT01620151
- Testing
- Extended neck with standard support or pillow
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pain Score Reduction, Effectiveness of Acetaminophen
Effectiveness Of Intravenous Vs Rectal Acetaminophen For Pain Management In Post Operative Neonates
This randomized controlled trial aims to evaluate the effectiveness of intravenous (IV) versus rectal acetaminophen for postoperative pain management in neonates.
- Conditions
- Pain Score Reduction, Effectiveness of Acetaminophen, Postoperative Pain Management in Neonates, Rescue Analgesia
- Trial name
- NCT06638086
- Testing
- Acetaminophen Suppositories, Acetaminophen Injection
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Rawalpindi Medical College
Post Operative Pain, Endodontic Treatment
Comparison of Post-operative Pain After Use of Endo-activator and Conventional Irrigation During Endodontic Treatment in Symptomatic Periapical Periodontitis
Introduction: The adequate removal of microorganisms, infected or necrotic pulp tissues and complete adequate seal of root canal system along with debridement is key to success of endodontic treatment.
- Conditions
- Post Operative Pain, Endodontic Treatment, Apical Periodontitis
- Trial name
- NCT06668662
- Testing
- Endoactivator, Conventional irrigation
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jinnah Sindh Medical University
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.
The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.
- Trial name
- NCT03347266
- Testing
- VVZ-149 injections
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Vivozon, Inc.
Post Operative Pain, Inguinal Hernia
Comparison of The Quadratus Lumborum Block and Ilioinguinal Iliohypogastric Nerve Block
Perioperative and postoperative pain control in pediatric patients is a frequently neglected issue. Regional anesthesia applications reduce adverse drug events by minimizing opioid consumption and provide effective and safe…
- Conditions
- Post Operative Pain, Inguinal Hernia, Quadratus Lumborum Nerve Block
- Trial name
- NCT05610943
- Testing
- ultrasound-guided quadratus lumborum nerve block, ultrasound-guided Ilioinguinal Iliohypogastric Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Anterior Cruciate Ligament (ACL) Tear, Arthroscopic Anterior Cruciate Ligament Reconstruction
Intraoperative Periarticular Injection in Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery
In this prospective, assessor-blinded, single-surgeon clinical trial, the goal was to validate the efficacy of PAI in aACLR surgery with a reduced opioid dose, while achieving similar pain relief with few adverse events.
- Trial name
- PAI in ACLR (NCT06630520)
- Testing
- Periarticular injection
- Where
- Taiwan
- Volunteers
- 288 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Post-op Pain
Adductor Canal Nerve Block Following Total Knee Arthroplasty
The purpose of this study is that an adductor canal nerve block (putting numbing medicine near the nerve) has been shown to produce excellent pain relief with less pain medication use after knee replacement surgery.The…
- Trial name
- NCT01939379
- Testing
- Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed., For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.
- Where
- United States
- Sponsor
- Loma Linda University
Postoperative Pain After Thoracic Surgery, Postoperative Pain
Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery
The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory…
- Conditions
- Postoperative Pain After Thoracic Surgery, Postoperative Pain, Thoracic Surgery, Video Assisted, Patient Controlled Analgesia
- Trial name
- NCT07610408
- Testing
- Fentanyl IV PCA, Tramadol IV PCA, Ibuprofen IV PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara Etlik City Hospital
Post Operative Pain
Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial
Femur fracture is a common injury occurring in the young due to trauma as well as amongst the elderly due to fall. Reduction and fixation of femur fractures pose a challenge to the anesthesiologist.
- Trial name
- NCT05484648
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Post Operative Pain, Craniofacial Pain
Sphenopalatine Ganglion Block and Pain Management in Neurosurgery
Post craniotomy pain is defined as headache developed up to 7 days from a craniotomy, not otherwise explained. A moderate to severe pain affects from 60 to 84% of patients.
- Trial name
- SpheNoPain (NCT05136625)
- Testing
- Sphenopalatine ganglion block, Standard Preparation
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- University Hospital of Ferrara
Hip Osteoarthritis
Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty
This clinical trial aims to assess the analgesic efficacy of ultrasound-guided FIB using different analgesic combinations administered into the iliac fascia compartment.
- Trial name
- FIB-PAIN (NCT06534697)
- Testing
- Naropin, 0.2% Injectable Solution in Sodium chloride, Naropin, 0.2% Injectable Solution in dextrose 5%, Dextrose 10 % in Water
- Volunteers
- 210 people
- Sponsor
- Foisor Orthopedics Clinical Hospital
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