Clinical trials: Post-operative Pain Control
Lumbar Osteoarthritis, Spondylosis
Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Patients undergoing spine surgery often have considerable pain post-operatively and frequently require opioid medication (Percocet, Norco, oxycodone, morphine, etc.) to control their pain postoperatively.
- Conditions
- Lumbar Osteoarthritis, Spondylosis, Lumbar Disc Disease, Spinal Stenosis
- Trial name
- NCT02700451
- Testing
- Ketorolac, Acetaminophen
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Tonsillectomy, Post-Operative Pain
Acupuncture for Post-tonsillectomy Pain Control in Children
A randomized, controlled, single-blinded study comparing conventional postoperative analgesia with paracetamol-on-demand with the same regime plus acupuncture.
- Conditions
- Tonsillectomy, Post-Operative Pain, Acupuncture
- Trial name
- NCT01285687
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ziv Hospital
Post-operative Dyspareunia
Dilators for Dyspareunia Prevention
This is a randomized clinical trial comparing rates of de novo dyspareunia in women with and without vaginal dilator use following surgery for pelvic organ prolapse with traditional posterior repair.
- Trial name
- DDS (NCT01299363)
- Testing
- Dilator use
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Pain, Postoperative
Caffeine Study for Pain Control Following Total Joint Replacement
A prospective, double blinded, single center, randomized controlled study to evaluate the efficacy of caffeine in combination with acetyl salicylic acid (ASA) in the management of postoperative pain in patients undergoing total…
- Trial name
- NCT04280263
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Rothman Institute Orthopaedics
Cesarean Section, Post Operative Pain
ESPB vs Intrathecal Morphine for Assessements of Quality of Recovery After Cesarean Section
Cesarean section is a surgical procedure that involves significant pain, which is managed through a multimodal pharmacological approach.The primary objective of the study is to evaluate the quality of hospitalization after…
- Trial name
- BELLMERE (NCT07202416)
- Testing
- Erector spinae plane block, Intrathecal morphine
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- AUSL Romagna Rimini
Analgesia, Post Operative Pain
Clinical Utility of the Numerical Verbal Scale (NVS) and the Pain and Functional Activity Scale (PFAS) in the Management of Rescue Analgesia in Acute Postoperative Pain. Randomized Study.
Adequate postoperative pain management, along with mobilization and early oral nutrition, is the foundation for optimal recovery after surgery.
- Conditions
- Analgesia, Post Operative Pain, Acute Pain, Functional; Anesthesia
- Trial name
- EVN/EDAF (NCT07310953)
- Testing
- Group A: Rescue analgesia if NVS>4, Group B: Rescue analgesia if NVSm > 4 + FAS C
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Inflammatory Bowel Diseases, Anesthesia
HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia
The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease
- Trial name
- HYSTERIA (NCT03261414)
- Testing
- Hypnosis, usual care
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Lille
Postoperative Pain, Acute, Shoulder Pain
Evaluating Intercostobrachial Nerve Block's Effect on Pain Control After Shoulder Replacement
Interscalene blocks are frequently performed to decrease postoperative pain after shoulder surgeries and are considered the gold standard for pain control after this type of surgery.
- Trial name
- NCT06042608
- Testing
- intercostobrachial nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Post Operative Pain
Value of IPACK Block (Interspace Between the Popliteal Artery and Capsule of Knee) With Spinal Anesthesia Versus Fentanyl Based Spinal Anesthesia for Knee Arthroscopic Meniscectomy
Postoperative analgesia is provided by local anesthesia combined with intrathecal narcotics. In addition, for the first 24 hours, this combination has a parenteral opioid sparing effect.
- Trial name
- NCT05833776
- Testing
- spinal anesthesia using hyperbaric bupivacaine 0.5% (3ml) with fentanyl (25ug)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Breast Cancer, Breast Neoplasms
Different Volumes of Erector Spinae Plane Block for Breast Surgery
Postoperative pain is an important issue in female patients underwent breast surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Diseases
- Trial name
- NCT05232084
- Testing
- Bupivacaine + Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Postoperative Analgesia
Analgesic Techniques for Robotic Prostatectomy Procedures
Robot-assisted radical prostatectomy and robot-assisted simple prostatectomy are minimally invasive procedures associated with reduced postoperative pain compared to open surgery.
- Trial name
- PROPAIN (NCT07483840)
- Testing
- Thoracic Erector Spinae Plane Block (ESPB-T), Rectus Sheath Block (RSB), Low-dose Spinal Analgesia (SA)
- Where
- Italy
- Volunteers
- 147 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Tonsillectomy, Tonsillitis
EXPAREL® for Pain After Tonsillectomy
The purpose of this study is to determine whether liposomal bupivacaine (long acting injectable anesthetic) provides greater post operative pain relief compared to the standard post operative pain regiment for tonsillectomy…
- Conditions
- Tonsillectomy, Tonsillitis, Post-operative Pain
- Trial name
- NCT02444533
- Testing
- Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Post Operative Pain
Comparing Between Ultrasound Guided Pectoral Nerve Block Versus Ultrasound Guided Mid-point Transverse Process Block for Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy
The aim of the study is to compare the effectiveness of ultrasound guided pectoral nerve block versus mid-point transverse process block for postoperative analgesia in patients undergoing modified radical mastectomy
- Trial name
- NCT06873893
- Testing
- Midpoint transverse process block, Pectoral Nerve Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Patient's Satisfaction, Depth of Anesthesia
The Effect of Esmolol Versus Dexmedetomidine on Postoperative Pain Control in Endoscopic Sinus Surgery: A Randomized Trial
Hypotensive techniques are associated with certain disadvantages. Hence, anesthesiologists are still in search of drugs with fewer side effects.
- Trial name
- NCT05703048
- Testing
- Esmolol Esterase, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Pain
Intravenous Lidocaine Infusion During Video-assisted Thoracic Procedures for Improved Pain Control
The purpose of this study is to determine whether intravenous lidocaine infusion during a video-assisted chest surgery is effective in reducing the pain involved after the surgery.
- Trial name
- NCT01277835
- Testing
- Lidocaine Infusion
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Saskatchewan
Opioid-use Disorder
The Effect of Buprenorphine Continuation for Patients With Opioid Use Disorder
There is limited guidance on the optimal management of buprenorphine perioperatively and both buprenorphine discontinuation and continuation are acceptable standards of care.
- Trial name
- NCT04981678
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MaineHealth
Kidney Calculi, Pain, Postoperative
Pre-induction Analgesia: Multimodel Regimen vs Aceteminophen for Post Ureteroscopy Pain
Adult patients with kidney stones undergoing surgical intervention with ureteroscopy with laser lithotripsy will be randomized to receive one of two different regimens of oral medications administered prior to induction of…
- Trial name
- MMPITR (NCT03549611)
- Testing
- Multimodal Oral Drug Regimen, Acetaminophen
- Sponsor
- Kevin J Flynn MD
Abdominal Muscles/Ultrasonography, Adult
Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair
Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage
- Trial name
- NCT01589796
- Testing
- TAP block
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stamford Anesthesiology Services, PC
Acute Pain
The Implementation of a Post-operative Communication App to Improve Pain Control and Opioid Use
Digital communication tools are becoming ubiquitous in healthcare, though their impact on patient/provider communication, healthcare utilization, and outcomes remains poorly established.
- Trial name
- NCT06124079
- Testing
- OPY interactive messaging service, Standard care
- Where
- United States
- Volunteers
- 3,442 people
- Sponsor
- University of Minnesota
Pain, Postoperative
Erector Spinae vs Fascia Iliaca Block in Hip Arthroplasty
The thoracic erector spinae plane (ESP) block was first described by Forero et al in September 2016. In their article, the authors presented the possibility of using this block as an option for the control of thoracic neuropathic…
- Trial name
- ESFIBHA (NCT03860324)
- Testing
- Single-shot erector spinae plane block, Single-shot fascia iliaca block
- Where
- Portugal
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
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