Clinical trials: Post-operative Pain Management
Acute Pain, Surgery
Auriculotherapy for Surgical Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Surgery, Shoulder Pain
- Trial name
- NCT03860259
- Testing
- Auriculotherapy cryopuncture device without nitrogen gas, Auriculotherapy cryopuncture device with nitrogen gas
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Postoperative Pain, Anesthesia, Regional
Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Ethics committee approval was taken on October 22, 2019, numbered 19/342. 120 adult patients who will undergo spine stabilization surgery between October 2019 and January 2020 in "Gülhane Training and Research Hospital" were…
- Conditions
- Postoperative Pain, Anesthesia, Regional, Spinal Stenosis
- Trial name
- NCT04193488
- Testing
- MTP block, ESP block, No Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Post Operative Urinary Retention
Effects of Thoracic Epidural Administered Ropivacaine Versus Bupivacaine on Bladder Function
Acute urinary retention is one of the most common complications after surgery and anesthesia. Micturition depends on coordinated actions between the detrusor muscle and the external urethral sphincter.
- Trial name
- NCT02414373
- Testing
- Ropivacaine 2mg/ml, Bupivacaine, 6 French transurethral dual channel catheter (Gaeltec, Dunvegan, Scotland)
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Peripheral Nerve Block, Pain Management
Anterior Suprascapular and Axillary vs. Interscalene Block for Analgesia and Diaphragmatic Function in Shoulder Surgery
Shoulder surgeries are among the most frequently performed orthopedic interventions and are often associated with moderate to severe postoperative pain.
- Conditions
- Peripheral Nerve Block, Pain Management, Diaphragm Protective Block, Upper Extremity
- Trial name
- NCT07739303
- Testing
- Interscalene Block, Combination of Axillary and Anterior Suprascapular Blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara Etlik City Hospital
Endometriosis; Peritoneum, Postoperative Pain
LTAP Block in Endometriosis Surgery - a Randomised Controlled Double-blind Trial
The purpose of this study is to compare the efficacy and safety of laparoscopically inserted transversus abdominis plane block (LTAP) in comparison to local wound analgesia in laparoscopic surgery due to suspected or diagnosed…
- Trial name
- NCT04735770
- Testing
- Postoperative pain management: LTAP block or local wound anesthesia with levobupivacaine
- Where
- Finland
- Volunteers
- 46 people
- Sponsor
- Oulu University Hospital
Total Knee Arthroplasty Postoperative Pain, Opioid Reduction After TKA
NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty
The goal of this clinical trial is to learn if the NEUROCUPLE device can reduce pain and opioid use after primary unilateral total knee arthroplasty (TKA) in adults.
- Trial name
- NCT07439666
- Testing
- NEUROCUPLE™ Patch, Enhanced Recovery After Surgery (ERAS) Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 274 people
- Sponsor
- Jacques E. Chelly
Post-cesarean Pain Control Quality
Comparisons Between Low Thoracic and Lumbar Epidural Analgesia on Postoperative Pain Low Thoracic v.s. Lumbar Epidural for Post-cesarean Pain
Whether low thoracic epidural analgesia improves postoperative cesarean pain qualities than conventional lumbar epidural analgesia?
- Trial name
- NCT03946982
- Testing
- low thoracic epidural, lumbar epidural
- Where
- Taiwan
- Volunteers
- 189 people
- Sponsor
- National Taiwan University Hospital
Ankle Osteoarthritis, Postoperative Pain
Suzetrigine for Postoperative Pain After Total Ankle Replacement
This study is testing whether adding a non-opioid pain medicine called suzetrigine (Journavx) to the usual combination of pain medicines helps people recover more comfortably after ankle replacement surgery.
- Conditions
- Ankle Osteoarthritis, Postoperative Pain, Acute Pain
- Trial name
- SUZY-TAA (NCT07795827)
- Testing
- Suzetrigine
- Volunteers
- 28 people
- Sponsor
- Soheil Ashkani Esfahani
Post Operative Pain
Comparaison of ESP Block and TAP Block
This study aim to compare the efficiency and the analgesic effect of Erector Spinal Plane Block versus TAP Block after laparoscopic cholecystectomy.
- Trial name
- NCT04176770
- Testing
- ESP Block, TAP Block
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Lumbar Spine Degeneration
A Randomized Trial of Exparel vs Saline in Opioid Reduction of Pain Management Following Lumbar Spine Surgeries.
The purpose of this study is to establish a relationship between liposomal bupivacaine surgical site injection and postop opioid utilization.
- Trial name
- Exparel (NCT04644796)
- Testing
- saline 0.9%, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Missouri-Columbia
Pain, Acute Post-Operative, Ambulatory Surgical Procedures
Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery
This study aims to predict pain after surgery in children of ages 1 to 3 years by using computer programming (machine learning). Participant children will be observed before, during, and after surgery.
- Conditions
- Pain, Acute Post-Operative, Ambulatory Surgical Procedures, Pediatric Pain, Pediatric Patient (1m-21y)
- Trial name
- NCT07274995
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Pain, Postoperative Nausea and Vomiting
Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate Tissue Expander (TE) Reconstruction
Primary Objective To determine if post-operative static pain scores differ between women undergoing bilateral mastectomy followed by bilateral immediate tissue expander reconstruction randomized either to ropivacaine- (treatment)…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life
- Trial name
- NCT02161705
- Testing
- Ropivacaine, Saline
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Johns Hopkins University
Skin Graft Wounds, Donor Site Complication
Aloe Vera vs Paraffin Tulle Dressings for Pain Management in Split Thickness Skin Graft Donor Sites
The goal of this clinical trial is to learn if Aloe Vera gel dressing helps reduce pain better than traditional paraffin-based tulle dressing at the donor site of split-thickness skin grafts in adult patients aged 18 to 60.
- Conditions
- Skin Graft Wounds, Donor Site Complication, Pain, Postoperative, Skin Transplantation
- Trial name
- AloePaTu (NCT07057557)
- Testing
- Aloe Vera Gel Dressing, Paraffin-Based Tulle Dressing
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- King Edward Medical University
Laparoscopic Cholecystectomy, Postoperative Pain Management
Sensory Analysis and Cutaneous Mapping of Different Regional Anesthesia Techniques
This prospective observational study aims to evaluate and compare the sensory block distribution and regression patterns of two regional anesthesia techniques - External Oblique Plane Block (EOPB) and Serratus Intercostal Plane…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain Management, Regional Anesthesia
- Trial name
- NCT07445854
- Testing
- External Oblique Plane Block (EOPB), Serratus Intercostal Plane Block (SIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Samsun University
Postoperative;Pain Management
Effects of Serratus Posterior Superior Intercostal Plane Block and Pectoralis Nerve Block in Coronary Artery Surgery
Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in all types of chest surgery, particularly coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06242431
- Testing
- Group serratus posterior superior intercostal plane block (SPSIPB), Group pectoralis nerve block (PECS-II)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Hitit University
Postoperative Pain
Comparison of Regional Block, Caudal Block and Wound Infiltration in Inguinal Hernitomy
Background: Although Inguinal herniotomy in children is taken as a day care procedure, post-operative pain management still remain controversial in these cases and superiority of wound infiltration, caudal block or regional block…
- Trial name
- Painseverity (NCT06386250)
- Testing
- regional block, Caudal block, Epidural
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- King Edward Medical University
Effect of Drug
Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment
Achieving effective pain control after endodontic treatment is still a disruptive event to all the clinicians. There is a knowledge gap regarding the effect of protease on postoperative pain following root canal treatment…
- Trial name
- NCT05479747
- Testing
- post operative analgesics
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pain, Agitation, Emergence
Management of PADIS in Emergency Intensive Care Unit
Investigate the prevalence of PADIS in EICU, as well as the awareness and clinical implementation status of medical staff towards PADIS.
- Conditions
- Pain, Agitation, Emergence, Delirium, Critical Illness
- Trial name
- NCT06339385
- Testing
- PADIS assessment
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Capital Medical University
Pain Management, Arthroplasty
Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Patients
This randomized controlled trial evaluates whether a standardized preoperative pain education session delivered by a nurse reduces postoperative pain intensity and surgical anxiety among adult elective orthopedic surgery patients…
- Conditions
- Pain Management, Arthroplasty, Knee Replacement, Hip Replacement
- Trial name
- Pain-Anxiety (NCT07362589)
- Testing
- Pain education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Yeditepe University
Spinal Surgery, Post-operative Care
Perioperative Rectal Methadone in Spine Surgery
Patients undergoing spinal surgery require pain control medication after their surgery. Investigators have successfully used intravenous Methadone to manage pain after surgery.
- Conditions
- Spinal Surgery, Post-operative Care, Post-operative Pain Management
- Trial name
- PROMISE (NCT06843174)
- Testing
- Rectal Methadone administer during spinal surgery
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
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