Clinical trials: Post-operative Pain Management
Pain, Postoperative
Methadone for Postoperative Pain
The aim of this study is to compare the efficacy of methadone versus morphine in dealing with postoperative pain, in laparoscopic cholecystectomy under total intravenous anesthesia (TIVA); Efficacy is defined in terms of the…
- Trial name
- NCT01833715
- Testing
- Morphine, Methadone, TIVA
- Where
- Chile
- Volunteers
- 86 people
- Sponsor
- Universidad de Valparaiso
Spine Surgery, Postoperative Pain Management
Intraoperative Placement of Vancomycin-impregnated Calcium Sulfate Beads Conjugated With Analgesics to Improve Spine Surgery Outcomes
The goal of this clinical trial is to learn if using calcium sulfate beads that contain vancomycin (an antibiotic) and pain-relieving medicines during spine surgery can improve recovery compared to standard care with intravenous…
- Trial name
- NCT07201987
- Testing
- Vancomycin (local, via calcium sulfate beads), Morphine (local, via calcium sulfate beads), Bupivacaine (local, via calcium sulfate beads)
- Volunteers
- 100 people
- Sponsor
- Ganesh M. Shankar
ERAS, Compliance
Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study
ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a…
- Conditions
- ERAS, Compliance, Quality of Life (QOL), Excercise
- Trial name
- Pre_ERAS (NCT07210164)
- Testing
- Ocoxin, Structured self-guided exercise
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Umbilical Hernia, Postoperative Pain Management
Ultrasound-Guided Transversus Abdominis Plane Block Versus Epidural Block for Umbilical Hernia Analgesia
This observational study aims to compare the postoperative analgesic effectiveness of ultrasound-guided transversus abdominis plane (TAP) block and single-dose epidural anesthesia in patients undergoing umbilical hernia surgery.
- Trial name
- NCT07327463
- Testing
- Ultrasound-Guided Transversus Abdominis Plane Block, Single-Dose Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sakarya University
Post Operative Pain
Ultrasound Guided Erector Spinae Plane Block vs Intrathecal Morphine
Total abdominal hysterectomy (TAH) is a major surgical procedure after which significant post-operative pain and discomfort are anticipated.
- Trial name
- NCT05218733
- Testing
- Ultrasound Guided Erector Spinae Plane Block, Intra thecal morphine., General anesthesia using intravenous fentanyl (1µgm/kg)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Vasectomy, NSAIDs
Post-Vasectomy Pain Study
This is a prospective four-armed unblinded randomized controlled trial to assess four different potential post-operative treatment options for men who undergo a vasectomy.
- Conditions
- Vasectomy, NSAIDs, Post-operative Care
- Trial name
- NCT07824258
- Testing
- Acetaminophen, ibuprofen, oxycodone
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Bilateral Superficial Cervical Block
Ultrasound Guided Bilateral Superficial Cervical Block for Post-operative Pain Therapy in Thyroid Surgery
Ultrasound Guided Bilateral Superficial Cervical Block for Postoperative Pain Therapy in Thyroid Surgery
- Trial name
- NCT03109691
- Testing
- bupivacaine, Dexamethasone, ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Chronic Pain, Pain, Intractable
An Implantable Spinal Cord Stimulation Pain Management System
There are many treatment options available for the management of chronic pain . Some include, but are not limited to, over-the-counter medications, Non-Steroidal Anti-Inflammatory Drugs, Physical Therapy, Transcutaneous…
- Conditions
- Chronic Pain, Pain, Intractable, Pain, Back Pain
- Trial name
- NCT00205855
- Testing
- Precision SCS
- Where
- 9 sites in United States
- Volunteers
- 65 people
- Sponsor
- Boston Scientific Corporation
Fear, Pain Management
Influence of Preoperative Fear on Pain and Postoperative Outcomes
Fear of anesthesia plays a crucial role in the perioperative setting and can negatively affect recovery. The main objective is to assess the relationship between fear of anesthesia, surgeries, and hospitals and poorer…
- Conditions
- Fear, Pain Management, Anxiety, Complications of Surgical Procedures or Medical Care
- Trial name
- POSPoFe (NCT06785389)
- Testing
- Fear of anesthesia, surgery and hospitals scale, State-Trait Anxiety Inventory, Nummerical Rating Scale for postoperative pain
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Kidney Transplant Recipient, Kidney Transplant Donor
Investigation of the Effects of Quadratus Lumborum Block Applied to Patients in Kidney Transplant Surgery
This study aims to determine the most effective and long-lasting pain relief method for post-operative analgesia in kidney donor and recipient patients in kidney transplantation programme with the least invasive and least drug…
- Trial name
- NCT06011850
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Pain, Postoperative
Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative duloxetine for treatment of acute postoperative pain have yielded positive outcomes with respect to reduction opioid consumption.
- Trial name
- NCT05115123
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Total Hip Arthroplasty, Postoperative Pain
Pericapsular Nerve Group (PENG) Block Combined With Periarticular Multimodal Drug Injection (PMDI) Versus Isolated PMDI for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial
Adequate pain control after total hip arthroplasty is crucial for early ambulation and patient satisfaction. However, there is no consensus about optimal pain control after post operation.
- Trial name
- NCT05320913
- Testing
- Pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI), isolated periarticular multimodal drug injection (PMDI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Total Knee Replacement
Femoral Block With or Without Ropivacaine for Analgesia After Total Knee Replacement (TKR)
Total knee replacement is a painful procedure. Many solutions have been proposed to diminish the post-operative doses of narcotics, including nerve blocks.
- Trial name
- TKR (NCT00910013)
- Testing
- Ropivacaine
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Hopital de l'Enfant-Jesus
Postoperative Pain, Sternotomy
Effect of Elastic Therapeutic Taping on Post-Sternotomy Pain in Coronary Artery Bypass Graft Surgery
This research study aims to find out whether elastic therapeutic taping can help reduce pain after heart surgery, specifically coronary artery bypass grafting (CABG), which is done using a surgical cut through the breastbone…
- Conditions
- Postoperative Pain, Sternotomy, Pain Management, Coronary Artery Bypass
- Trial name
- NCT06910215
- Testing
- Elastic therapeutic taping, Therapeutic Taping on Non-Surgical Areas
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Abant Izzet Baysal University
Postoperative Pain
Epidural Catheter and Surgically Implanted Rectus Sheath Catheter in Management of Postoperative Pain
One hundred and twenty patients at age range from 18 to 60 undergoing laparotomy was enrolled in this study. Patients were randomly assigned to two groups 60 in epidural group and the other 60 patients in rectus catheter group.
- Trial name
- NCT04755725
- Testing
- Epidural catheter, rectus sheath catheter
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Menoufia University
Postoperative Pain Management, Total Knee Arthroplasty
Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal Morphine
To evaluate whether pregabalin and/or celecoxib could improve analgesic efficacy of intrathecal morphine for patients after total knee arthroplasty.
- Trial name
- PCTKA (NCT01344213)
- Testing
- Pregabalin, Celecoxib, Pregabalin with celecoxib
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Pain
Is Paracetamol an Effective Treatment for Chronic Moderate Pain in the Newborn After Operative Vaginal Delivery?
There are many reasons for using a vacuum apparatus or forceps to assist in delivering a baby. The traction and pressure on the baby's head due to the vacuum apparatus or forceps may cause pain and discomfort for some time after…
- Trial name
- NCT00488540
- Testing
- Paracetamol
- Where
- 3 sites in Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Complication of Anesthesia
Assessing Peripheral Nerve Block Scoring Systems for Intra-Operative and Post-Operative Analgesia
The purpose of this study is to determine if Peripheral Nerve Block scoring systems are effective in predicting the achievement of intra-operative anaesthesia and post-operative analgesia.
- Trial name
- NCT02041806
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- The Adelaide and Meath Hospital
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