Clinical trials: Post-operative Pain Management
Pain, Postoperative
ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
Comparison of standard post-operative cesarean surgery pain management with regional post-op pain control.
- Trial name
- qlcsection (NCT03261193)
- Testing
- ITM + Bupivacaine QLB
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Nicholas Schott
Inflammatory Bowel Diseases, Anesthesia
HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia
The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease
- Trial name
- HYSTERIA (NCT03261414)
- Testing
- Hypnosis, usual care
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Lille
Pain, Postoperative, Non-Opioid Pain Management
Virtual Reality After Breast Reconstruction Surgery
This is a pilot study of virtual reality (VR) non-opioid management for women undergoing mastectomy and implant-based reconstruction.
- Conditions
- Pain, Postoperative, Non-Opioid Pain Management, Virtual Reality
- Trial name
- VR4BR (NCT03801616)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Virtual Reality, Pain, Postoperative
Virtual Reality for Post Operative Pain Management After Total Knee Arthroplasty
Virtual reality has been used for acute pain management (burn patients) with positive results. Hypnosis has known beneficial effects on patients in the peri-operative setting.
- Conditions
- Virtual Reality, Pain, Postoperative, Knee Arthropathy, Anesthesia
- Trial name
- VR4POPKA (NCT03665233)
- Testing
- VR
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Clinique Saint-Jean, Bruxelles
Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture
The goal of this clinical trial is to learn whether suzetrigine (Journavx®), when added to standard multimodal pain management, can reduce opioid use while providing adequate pain control in adults undergoing surgery for an acute…
- Trial name
- STRIDE-HIP (NCT07905404)
- Testing
- Suzetrigine (Journavx)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Beth Israel Deaconess Medical Center
Delirium, Hip Fracture
Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.
Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality.
- Trial name
- RASAPOD (NCT02689388)
- Testing
- Femoral Nerve Block
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Auckland City Hospital
Postsurgical Pain Management
A Study on TLC590 for Managing Postsurgical Pain
This Phase 2 open-label trial investigates the pharmacokinetics (PK), pharmacodynamics, and safety profile of TLC590 across various surgical procedures.
- Trial name
- NCT06574269
- Testing
- TLC590, Ropivacaine
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- TLC Biopharmaceuticals, Inc.
Pain, Postoperative
Comparison Of Erector Spinae Plane Block With Transversus Abdominis Plane Block For Postoperative Pain Management In Patients Undergoing Total Abdominal Hysterectomy
Hysterectomy is the second most common major Obstetric/gynecology procedure worldwide and one of the most common procedures in our institute. Post-operative pain is one of the most common complications following hysterectomy.
- Trial name
- NCT05521841
- Testing
- Erector Spinae Plane Block(Bilateral Ultrasound Guided Erector Spinae Plane Block), Transversus abdominis plane block(Bilateral Ultrasound-guided bilateral Transversus abdominis plane block)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Laparotomy
IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia
The purpose of this research study is to determine if the two common ways of administering additional opioids (morphine like substance, narcotic) with an epidural, either mixed in the epidural solution or given separately through…
- Trial name
- NCT06559969
- Testing
- Intravenous administered opioid, Epidural administered opioid
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Iowa
Pain After Total Knee Arthroplasty, Pain Management
Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement
The goal of this clinical trial is to see whether a combined distal femoral nerve block improves pain relief after total knee replacement in adults having planned surgery.
- Trial name
- FEM-COMB (NCT07629388)
- Testing
- Combined distal femoral nerve block, Saphenous nerve block alone, Standard perioperative care in both groups
- Where
- France
- Volunteers
- 240 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Post-Operative Pain
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™) for the Treatment of Post-Operative Pain in Patients After Open Abdominal Surgery
The purpose of this study is to compare the efficacy and safety of the Sufentanil NanoTab PCA System/15 mcg to the Placebo Sufentanil NanoTab PCA System for the management of acute moderate to severe post-operative pain after…
- Trial name
- NCT01539642
- Testing
- Sufentanil NanoTab PCA System/15 mcg
- Where
- 12 sites in United States
- Volunteers
- 172 people
- Sponsor
- Talphera, Inc
Pain, Pain, Postoperative
Intervention Study to Enhance Patients' Pain Management After Cardiac Surgery
The main objective of this randomized controlled trial is to evaluate the effect of an intervention formed as a pain booklet provided to patients at discharge from hospital following cardiac surgery.
- Conditions
- Pain, Pain, Postoperative, Other Functional Disturbances Following Cardiac Surgery
- Trial name
- NCT01976403
- Testing
- Pain Booklet
- Where
- Norway
- Volunteers
- 416 people
- Sponsor
- Oslo Metropolitan University
Post Operative Pain
Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic Cholecystectomy
This study is aimed to determine the post operative pain after laparoscopic cholecystectomy by dividing patients into three different group.
- Trial name
- NCT05231941
- Testing
- Lidocaine IV, Ropivacaine
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Postoperative Pain
TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain
In this randomized, controlled, double-blinded trial we plan to evaluate post-operative pain relief after laparoscopic-assisted Transversus Abdominis Plane (TAP) block using liposomal bupivacaine plus bupivacaine versus…
- Trial name
- LATAP (NCT02400645)
- Testing
- Pre-incisional wound infiltration, Laparoscope to place TAP block with liposomal bupivacaine, Liposomal bupivacaine
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Toxicology, Bariatric Surgery Analgesia
Preoperative Toxicological Screening on Perioperative Anesthetic Management
Background: Preoperative substance use is a growing concern in patients undergoing metabolic bariatric surgery (MBS), but its impact on short-term outcomes remains debated.
- Conditions
- Toxicology, Bariatric Surgery Analgesia, Bariatric Surgery, Substance Use
- Trial name
- NCT07100314
- Testing
- Multi-Drug One Step Screen Test Panel (Urine)
- Where
- Egypt
- Volunteers
- 1,260 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Postoperative Analgesia
Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy.
Postoperative pain after laparoscopic cholecystectomy remains clinically relevant. This double-blinded randomized controlled trial compares the analgesic efficacy of landmark-guided Erector Spinae Plane Block (ESPB) and subcostal…
- Trial name
- NCT07469410
- Testing
- Landmark guided Erector Spinae Block, Landmark guided Transversus Abdominis Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Cancer Pain
Effect of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain in Knee Tumor Excision
the aim of this study is to determine the analgesic effect of iPACK in combination to ACB after the excision of tumors around the Knee regarding the following: Time to the 1st rescue analgesia. Postoperative morphine consumption.
- Trial name
- NCT07382297
- Testing
- adductor canal block with iPACK, control group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute, Egypt
Complex Obstetric Surgery, Perioperative Pain Management
COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean…
- Conditions
- Complex Obstetric Surgery, Perioperative Pain Management, Cesarean Delivery, Postoperative Pain Control
- Trial name
- COMFORT (NCT06925152)
- Testing
- Bupivicaine intervention arm
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Tennessee
Hip Fractures
PENG Block Versus Fascia Iliaca Block for Pre- and Post-Operative Analgesia in Elderly Patients With Hip Fracture
Clinical controled trial to compare between pericapsular Nerve Group Block and Fascia Iliaca Block to find the best way to provide analgesia for elderly patients with hip fracture in the pre- and post-operative periods.
- Trial name
- NCT04564326
- Testing
- Pericapsular nerve Group block, Facia Iliaca block, Fentanyl
- Volunteers
- 51 people
- Sponsor
- Zagazig University
Orthognathic Surgery, Postoperative Pain
Kinesio Taping vs Rigid Compression Taping Following Bimaxillary Orthognathic Surgery
Postoperative facial swelling and pain are common complications following corrective jaw surgery (bimaxillary orthognathic surgery).
- Conditions
- Orthognathic Surgery, Postoperative Pain, Edema
- Trial name
- NCT07833540
- Testing
- Kinesio Taping, Rigid Compression Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
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