Clinical trials: Post-operative Pain Management
Pain Management
Imagined Acupuncture for Postoperative Pain After Spinal Surgery
The goal of this clinical trial is to evaluate whether imagined acupuncture can reduce postoperative acute pain in adult patients undergoing spinal surgery.
- Trial name
- NCT07197710
- Testing
- video-guided acupuncture imagery treatment (VGAIT), Education video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Jingping Wang, MD, Ph.D.
Opioid Use
Opioid Analgesic Reduction Study
The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain management, a double-blind, stratified…
- Trial name
- OARS (NCT04452344)
- Testing
- opioid-containing analgesic, two over-the-counter analgesics
- Where
- 5 sites in United States
- Volunteers
- 1,815 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Intubation; Difficult or Failed, Airway Complication of Anesthesia
Neural Integrity Monitor Electromyogram (NIM-EMG) Endotracheal Tube Intubation With Video Laryngoscope
Laryngeal nerve monitoring is performed to prevent intraoperative nerve damage in thyroidectomy operations. NIM-EMG intubation tube is used while monitoring the recurrent laryngeal nerve.
- Conditions
- Intubation; Difficult or Failed, Airway Complication of Anesthesia, Pain, Postoperative, Anesthesia Intubation Complication
- Trial name
- NCT05366582
- Testing
- Macintosh Laryngoscope, Video Laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postoperative Pain
COMPARISON OF TRANSVERSUS ABDOMINIS PLANE BLOCK, LOCAL ANESTHETIC INJECTION TO THE PORT SITES AND INTRAPERITONEAL LOCAL ANESTHESIA APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN PATIENTS WITH LAPAROSCOPIC APPENDECTOMY
The most important determinant of the recovery in abdominal surgery is postoperative pain. Postoperative pain can be explained by 2 pathways connected to the peritoneum; The first is the parietal peritoneum, whose innervation is…
- Trial name
- APPENDECTOMY (NCT03790020)
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Analgesia
Medico-economic Evaluation of Sublingual PCA (Zalviso) Versus Oxycodone-PCA in the Management of Postoperative Pain.
More than 230 million surgical operations are been realized all over the world every year. A surgical intervention can cause postoperative acute pain.
- Trial name
- MEZO (NCT03882320)
- Testing
- Patient Controlled Analgesia (PCA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Pain, Postoperative
The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy
Recent clinical studies in abdominal surgery have shown that the use of Xylocaine® parenterally intraoperative at plasma concentrations below the toxic threshold of 5 .mu.g / ml, had an analgesic effect and decreased…
- Trial name
- KETALIDO (NCT02969733)
- Testing
- Xylocaine, Ketamine, isotonic saline serum intravenous administration
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Pain
Early Post-Operative Pain Control Following Wrist Operations
The purpose of this study is to demonstrate improved pain control and outcomes in wrist operations with the use of a long-acting local anesthetic, EXPAREL, when compared to the use of the standard local anesthetic, Marcaine.
- Trial name
- NCT02052180
- Testing
- Exparel, Marcaine (Control)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Tennessee
Shoulder Injuries, Pain, Postoperative
Battlefield Acupuncture Following Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to standard post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation…
- Conditions
- Shoulder Injuries, Pain, Postoperative, Acupuncture, Ear, Pain Management
- Trial name
- BFA (NCT04094246)
- Testing
- Battlefield Acupuncture, Standard post-surgical rehabilitation
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Keller Army Community Hospital
Bariatric Surgery Candidate, Post-operative Pain
Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over…
- Trial name
- NCT06077214
- Testing
- Treatment with liposomal bupivacaine, Treatment with standard bupivacaine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Virginia Commonwealth University
Post-Operative Pain, Chronic
Intra-articular Analgesia Versus Adductor Canal Block for Arthroscopic Knee Surgery
This study is a randomized study that compares two commonly used post-operative pain reducing techniques by measuring the level of pain and use of pain medication after knee surgery.
- Trial name
- NCT05004506
- Testing
- Adductor Canal Block, Intra-articular Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loyola University
Post-operative Pain Management
Efficacy of Exparel (TM) on Post-operative Pain After Laparoscopic Gastric Bypass Using Circular EEA Stapler
This will be a comparative study between two cohorts of patients undergoing Roux-en-Y Gastric bypass. One cohort (75 patients) will receive FDA approved Exparel® (liposome bupivacaine injection solution) injections…
- Trial name
- NCT03187379
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Matthew Kroh
Open Heart Surgery
Benefit of Peri-operative Bilateral ESP Catheters for Enhanced Recovery for Cardiac Surgery (ERCS)
To demonstrate if the addition of peri-operative regional analgesia by Bilateral ESP catheters improves the enhanced recovery program after open heart surgeries for the duration of hospitalisation, quality of analgesia…
- Trial name
- ESP_ERCS (NCT04506762)
- Testing
- Regional analgesia
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- Vinmec Healthcare System
Breast Cancer, Breast Cancer Female
Study of Nerve Block Pain Management in Patients Undergoing a Double Mastectomy With Immediate Reconstruction
The purpose of this study is to determine if the injection site or sites used for administering pain medication (nerve blocks) before a double mastectomy with immediate reconstruction with tissue expanders reduce the need for…
- Trial name
- NCT04016376
- Testing
- PVB Protocol, PECS-1, Serratus
- Where
- United States
- Volunteers
- 1,507 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pain, Pain Management
Ultrasound-guided Interscalene Block Versus Infraspinatus-Teres Minor Plane Block in Shoulder Arthroscopy
This study aims to compare the efficacy and safety of ultrasound-guided Interscalene block (ISB) versus Infraspinatus-Teres minor (ITM) interfacial plane block in shoulder arthroscopic surgery.
- Conditions
- Pain, Pain Management, Pain Management in Postoperative Care
- Trial name
- (ISB)-(ITM) (NCT07016386)
- Testing
- Group A: will receive an ultrasound-guided interscalene block (ISB), Group B:will receive an ultrasound-guided infraspinatus-teres minor (ITM) interfacial plane block
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Kidney Stones
Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy
Here is a patient-friendly, ClinicalTrials.gov-compliant Brief Summary written in plain language, avoiding technical jargon as much as possible while remaining accurate.
- Trial name
- BLOCK-PCNL (NCT07359391)
- Testing
- Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Breast Cancer
Impact of Regional Anesthesia on Chronic Post-operative Pain
Approximately 55,000 cases of breast cancer are diagnosed in Italy every year and the first-line therapy for carcinoma in situ, stage I, II and IIIA is surgical removal of the tumour.
- Trial name
- IRACPoP (NCT05876390)
- Testing
- Breast surgery, analgesia
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Niguarda Hospital
Arthropathy of Knee, Early Ambulation
Peripheral Nerve Blocks and Postoperative Pain and Mobilization After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is frequently associated with significant postoperative pain, which may delay early mobilization and negatively affect functional recovery.
- Conditions
- Arthropathy of Knee, Early Ambulation, Pain, Postoperative, Pain Management
- Trial name
- NCT07442123
- Testing
- Fascia Iliaca Plane Block, Adductor Canal Block + IPACK Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Post Operative Pain Control
Perioperative Epidural Trial (POET) Pilot Study
To investigate if the use of perioperative neuraxial blockade reduces post-operative mortality and cardiorespiratory events compared to intraoperative general anesthesia AND postoperative IV narcotic analgesia.
- Trial name
- NCT00221260
- Testing
- anesthesia
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of British Columbia
Gynecologic Cancers, Postoperative Pain Management
Effectiveness of Combined Fascial Plane Blocks for Postoperative Pain in Gynecologic Oncology Surgery
The goal of this prospective observational study is to compare the effectiveness of different postoperative analgesic techniques in patients undergoing major abdominal surgery for gynecologic oncology.
- Trial name
- NCT07312825
- Testing
- Group 1:The Transversus Abdominis Plane (TAP) block, Group 2: TAP Block + Quadratus Lumborum Block (QLB), Group 3: TAP Block + Rectus Sheath Block (RSB)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
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