Clinical trials: Post-operative Pain Management
Post-operative Pain
Liposomal Bupivacaine for Post Operative Pain After Knee Replacement Surgery
Continuous femoral nerve blocks (CFNB) provide effective pain control to patients undergoing total knee replacement (TKR). However the resulting motor blockade can lead to decreased quadriceps muscle strength and delayed…
- Trial name
- NCT02274870
- Testing
- Liposome Bupivacaine, Bupivacaine HCl
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Northwell Health
Acute Post Operative Pain, Chronic Post Operative Pain
Combined Use of Naldebain® ER Injection and Precedex® After VATS
The goal of this clinical trial is to investigate the effects of combined use of Naldebain® ER Injection and Precedex® in patients received video-assisted thoracoscopic surgery.
- Conditions
- Acute Post Operative Pain, Chronic Post Operative Pain, Postoperative Complications
- Trial name
- NCT06176222
- Testing
- PRECEDEX INJ★ 2ML, Normal saline
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain
Improving Pain Management and Decreasing LOS After Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
This two arm, patient blinded, randomized, post market clinical trial in a single orthopedic hospital will determine whether there is improved pain management and decreased length of stay when comparing standard of care pain…
- Trial name
- NCT05307341
- Testing
- sufentanil
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- More Foundation
Postoperative Pain
Role of Opioids in Epidural Solutions
It is unclear whether addition of opioids to epidural solutions for postoperative analgesia is beneficial. In this multicenter randomized double-blinded trial, we aim to test the primary hypothesis that epidural solutions…
- Trial name
- NCT04251962
- Testing
- Bupivacaine, Fentanyl
- Where
- Israel
- Volunteers
- 135 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Postoperative
Does Preoperative Pain Levels by Venipuncture Predict Late Postoperative Pain Levels?
This study wishes to investigate if pain by peripheral venous cannulation (PVC) preoperatively, will predict pain levels after 24 h postoperatively.
- Trial name
- NCT03439566
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Zealand University Hospital
Scoliosis
Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery
The purpose of this study is to evaluate the effects of continuous local anesthetic delivery on the immediate post-op recovery of patients undergoing spinal fusion surgery for congenital or idiopathic scoliosis.
- Trial name
- NCT00508066
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shriners Hospitals for Children
Post Operative Pain, Impacted Third Molar Tooth
Pain Control Following Third Molar Surgery
In this study, the investigators recruited patients undergoing surgical removal of impacted third molar teeth. Participants will be randomly divided into two groups Group 1: The patient will receive 400mg of ibuprofen plus 1000mg…
- Trial name
- NCT06514222
- Testing
- Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given together every 8 hours, Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given alternatively every four hours
- Where
- United Arab Emirates
- Volunteers
- 56 people
- Sponsor
- University of Sharjah
Pain Management, Postoperative Pain
Effects of S-ketamine on Perioperative Opioid Consumption
This study is a triple-blind randomized controlled trial conducted at a tertiary care hospital in Brussels. It investigates whether a single dose of S-ketamine can reduce opioid (morphine) consumption in the first 24 hours after…
- Conditions
- Pain Management, Postoperative Pain, Opioid Consumption, Postoperative, Opioid Analgesia
- Trial name
- NCT07528651
- Testing
- Esketamine at low dose, Saline (0.9% NaCl)
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Post Operative Pain, Emergence Agitation
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Sphenopalatine Ganglion Block for Functional Endoscopic Sinus Surgery
This prospective, randomized, double-blind, controlled trial will compare the efficacy and safety of dexmedetomidine versus dexamethasone as adjuvants to bupivacaine in ultrasound-guided bilateral sphenopalatine ganglion block…
- Conditions
- Post Operative Pain, Emergence Agitation, Functional Endoscopic Sinus Surgery
- Trial name
- NCT07911202
- Testing
- Bupivacaine & normal saline, Dexmedetomidine & Bupivacaine., Dexamethasone & Bupivacaine.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska
Pain Management, Postoperative Care
The Effect of the Strategic Game Tangram on Postoperative Patient Outcomes
The aim of this study was to investigate the effects of playing tangram game after surgery on pain, fatigue and comfort levels in patients undergoing abdominal surgery.
- Conditions
- Pain Management, Postoperative Care, Nursing Care
- Trial name
- NCT07031271
- Testing
- Tangram game
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Aydin Adnan Menderes University
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Primary Total Knee Arthroplasty
Quadriblock Versus "IPACK + Femoral Triangle Block + Obturator Nerve Block" in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- QuITO (NCT04499716)
- Testing
- IPACK, Femoral triangle block, Obturator nerve block
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Clinique Medipole Garonne
Pain, Postoperative, Pediatric Disorder
The Efficacy of Acupuncture in the Management of Postoperative Pain in the Pediatric Intensive Care Unit
Pain is an unpleasant sensory and emotional experience resulting from tissue damage. Pain management is typically conducted according to the World Health Organization (WHO) pain management ladder.
- Conditions
- Pain, Postoperative, Pediatric Disorder, Acupuncture, Acupuncture, Ear
- Trial name
- NCT06390007
- Testing
- Press needle acupuncture
- Where
- Indonesia
- Volunteers
- 70 people
- Sponsor
- Universitas Indonesia
Postoperative Pain
COMPARISON OF INTRAOPERATIVE LOCAL ANESTHETIC APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS
Since 1987, laparoscopic cholecystectomy has become the standard procedure for gallbladder stones and lesions. Complications due to improvements in laparoscopy and increased surgical experience have decreased day by day, but…
- Trial name
- NCT03790007
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Post Operative Analgesia, Rebound Pain
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A
Rebound pain after peripheral nerve blocks reduces the benefits of regional anesthesia and increases opioid consumption. This rebound pain most likely results from suboptimal pain management, as patients receiving a peripheral…
- Conditions
- Post Operative Analgesia, Rebound Pain, Post Operative Pain, Acute
- Trial name
- REBOUND (NCT07666971)
- Testing
- Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
to Evaluate the Effects of Clinical Hypnosis on Post-operative Pain, Following Colectomy Operations
Hypnosis for Colectomies as Postoperative Pain Management
The present study intends to assess the feasibility, value and direction of conducting a future, full scale randomised controlled trial, to evaluate the effects of clinical hypnosis on post-operative pain, following colectomy…
- Trial name
- Hypnopal (NCT06499909)
- Testing
- Hypnosis
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Somerset NHS Foundation Trust
Lumbar Spinal Stenosis, Lumbar Spinal Instability
Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients
Patients presenting for lumbar spine surgery experience pain related to their spine condition. Following surgery, these patients also experience surgical pain resulting from disruption of skin, muscle tissue, vertebrae…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spinal Instability, Lumbar Spine Degeneration
- Trial name
- IPaRO (NCT03088306)
- Testing
- Standard analgesia use [Oxygen], Standard analgesia use [Hydromorphone], Standard analgesia use [Volatile Anesthesia]
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Johns Hopkins University
Ophthalmic Surgery, Postoperative Pain Management
Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery
The goal of this clinical trial is to learn if Anrikefon works as well as nalbuphine to control postoperative pain in adults undergoing ophthalmic surgery under general anesthesia.
- Conditions
- Ophthalmic Surgery, Postoperative Pain Management, Opioid Analgesia
- Trial name
- NCT07269106
- Testing
- Anrikefon, Nalbuphine
- Where
- 3 sites in China
- Volunteers
- 204 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
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