Clinical trials: Post-operative Pain Management
Pain, Postoperative Pain
Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt…
- Trial name
- NCT04835116
- Testing
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg., paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Sternotomy, Postoperative Delirium
Comparison of the Postoperative Analgesic Effectiveness of Erector Spinae Plane Block Versus Its Combination With Superficial Parasternal Intercostal Plane Block Within the ERACS Program
This prospective, randomized, double-blind, parallel-group clinical trial within the Enhanced Recovery After Cardiac Surgery (ERACS) program compares postoperative analgesic effectiveness of bilateral erector spinae plane (ESP)…
- Conditions
- Sternotomy, Postoperative Delirium, Postoperative Pain Management
- Trial name
- ERACS-ESP-SPIP (NCT07304635)
- Testing
- Procedure: Erector Spinae Plane (ESP) Block, Erector Spinae Plane (ESP) Block + Superficial Parasternal Intercostal Plane (SPIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara University
Post Operative Pain
Pectointercostal Block for Postoperative Pain Management After Sternotomy
This randomized, controlled study is designed to assess the quality of analgesia provided by ultrasound-guided bilateral pectointercostal facial block in children undergoing cardiac surgery via midline sternotomy.
- Trial name
- NCT05552417
- Testing
- Pectointercostal facial plan block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain, Regional Anaesthsia
Parasternal and Adductor Canal Blocks in CABG
This randomized controlled trial evaluates the effectiveness of different postoperative analgesic strategies in patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Postoperative Pain, Regional Anaesthsia, Pain Management
- Trial name
- NCT07599748
- Testing
- parasternal block, Parasternal block + Adductor canal block, conventional analgesic regimen
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Zonguldak Bulent Ecevit University
Osteoarthritis
Does Optimal Control of Pre-operative Chronic and Acute Pain Predict Improved Function After Orthopedic Surgery?
Despite the development of new pain medications, the prevalence of persistent postoperative pain (for more than three to six months) remains alarmingly high.
- Trial name
- NCT00581685
- Testing
- Pregabalin, Celecoxib
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Postoperative Pain Management
Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study
The purpose of this study is to evaluate the safety and efficacy of lidocaine infusion in acute pain management following open abdominal surgery, including opiate use after surgery and the incidence of postoperative nausea and…
- Trial name
- NCT06725485
- Testing
- Low-Dose Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Methodist Hospital Research Institute
Post-operative Pain, Postoperative Nausea
Trial of a Transversus Abdominis Plane (TAP) Block in Laparoscopic Colorectal Surgery
Keyhole surgery for bowel disease has brought great benefits, enabling patients to recover quicker from surgery and so return to normal activities.
- Conditions
- Post-operative Pain, Postoperative Nausea, Postoperative Complications
- Trial name
- NCT00830089
- Testing
- Levobupivicaine 0.25%
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- University of Nottingham
Breast Cancer Female, Postoperative Pain
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study
Breast cancer is one of the most common types of cancer among women worldwide. (1) Breast-conserving surgery or mastectomy is indicated for the majority of patients with this type of cancer.
- Conditions
- Breast Cancer Female, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT04875559
- Testing
- Standardised multimodal pain treatment regimen
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Zealand University Hospital
Post Operative Pain
Patient Satisfaction and Pain Control Following Reconstructive Vaginal Surgery
The investigators hypothesize that patient controlled analgesia (PCA) provides superior pain relief and patient satisfaction when compared to scheduled intravenous analgesia following vaginal reconstructive surgery.
- Trial name
- NCT01442818
- Testing
- Dilaudid PCA, Dilaudid IV Scheduled
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- TriHealth Inc.
Cannabis Use, Opioid Consumption
A Comparison of Post-Operative Analgesia Requirements In Recreational Cannabis Users Versus Cannabis Naïve Inflammatory Bowel Disease Patients
Cannabis is a drug that is widely used for recreational purpose. In most patients undergoing surgery, opioids are the most widely used mode of pain relief, during and following surgery.
- Trial name
- NCT04055662
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Mount Sinai Hospital, Canada
Post Operative Pain, Regional Anesthesia Morbidity
Does ESP Block Reduce Pain and Opiates Consumption After Surgery
The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72…
- Conditions
- Post Operative Pain, Regional Anesthesia Morbidity, Opioid-Related Disorders, Chronic Pain
- Trial name
- NCT05512897
- Testing
- erector spinea plane block
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michael Dubilet MD
Pain, Postoperative
Erector Spinae Plane Block in Liver Transplantation Donors
Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision.
- Trial name
- NCT05406388
- Testing
- Erector Spinae Plane Block, Intravenous fentanyl patient control device
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medipol University
Postoperative Pain
Quality of Postoperative Pain Management Following Thoracic Surgery
The purpose of this study is to assess the quality of postoperative pain management in a Canadian teaching hospital following thoracic surgery.
- Trial name
- NCT01616550
- Testing
- Assessment of pain using the Brief Pain Questionnaire, Assessment of pain relief using a Verbal Numeric Scale (VNS), Assessment of patient' satisfaction with pain relief
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acut Postoperative Pain, Erector Spinae Plane Block
Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is considered the gold standard for the surgical treatment of benign gallbladder diseases; however, despite its minimally invasive nature, a significant proportion of patients experience substantial…
- Conditions
- Acut Postoperative Pain, Erector Spinae Plane Block, Intertransverse Process Block
- Trial name
- NCT07504705
- Testing
- Intertransverse Process Block, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Preoperative Anxiety, Virtual Reality
The Effect of Virtual Reality Education on Preoperative Anxiety, Postoperative Pain, and Sleep in Patients Undergoing Colon Surgery
The effect of patient education given to patients undergoing colon surgery using virtual reality in the preoperative period on preoperative anxiety, postoperative pain and sleep is the subject of this study.
- Conditions
- Preoperative Anxiety, Virtual Reality, Postoperative Pain Management, Postoperative Sleep
- Trial name
- NCT07297095
- Testing
- preoperative patient education via virtual reality device
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Yildirim Beyazıt University
Lumbar Spine Stenosis, Lumbar Spine Degeneration
OpalGenix- Personalized Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research.
- Trial name
- NCT05452694
- Where
- 3 sites in United States
- Volunteers
- 235 people
- Sponsor
- OpalGenix, Inc
Pain, Postoperative
Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy
Hysterectomy is the most common major gynecologic surgery performed in the US and is performed for a variety of indications including malignancy, pelvic mass, endometriosis, leiomyoma, and pelvic organ prolapse.
- Trial name
- RA-TLH (NCT04429022)
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Post Operative Pain Control, Endodontic Treatment
Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain
The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic…
- Trial name
- NCT06894069
- Testing
- Dexamethasone
- Volunteers
- 80 people
- Sponsor
- University of Jordan
Postsurgical Pain, Cesarean Section
Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section
Inadequate postoperative pain management can lead to physical and psychological distress in patients as well as impact surgical wound healing and increase the risk of developing postoperative delirium and cardiopulmonary and…
- Conditions
- Postsurgical Pain, Cesarean Section, Chronic Post-surgical Pain
- Trial name
- NCT06344169
- Testing
- Sebacoyl Dinalbuphine Ester, Morphine
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Postoperative Cognitive Dysfunction, Orthopedic Procedures
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
This study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia.
- Conditions
- Postoperative Cognitive Dysfunction, Orthopedic Procedures, Postoperative Pain Management, Hip Fracture
- Trial name
- REMIND-ORTHO (NCT07113483)
- Testing
- Midazolam, REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO]
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition