Clinical trials: Post-operative Pain Management
Post-operative Pain
Comparing Perioperative Outcomes in Pain Control
This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an orthopaedic injury requiring surgery.
- Trial name
- NCT05690282
- Testing
- Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Postoperative Pain Management, Postoperative Nausea and Vomiting
LAPOFAR Trial: Opioid-Free vs. Remifentanil Anesthesia in Laparoscopic Cholecystectomy
This study was a single-center, prospective, randomized clinical trial designed to compare the effects of opioid-free anesthesia (OFA) with standard opioid-based anesthesia during elective laparoscopic cholecystectomy.
- Conditions
- Postoperative Pain Management, Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy, Opioid-free Anesthesia
- Trial name
- LAPOFAR (NCT07307625)
- Testing
- Lidocaine + Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Laparotomy, Hepatic Resection
Continuous Preperitoneal Infusion of Ropivacaine After Open Liver Resection: Effect on Post-operative Recovery and Morbidity.
Intravenous morphine Patient-Controlled analgesia is gold standard on post - operative liver resection. But, opioids tend to be ineffective for pain that is associated with movement and have significant short-term side effects…
- Trial name
- ROPIHEP (NCT01890408)
- Testing
- wound infusion ropivacaine
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Irreversible Pulpitis
Dexketoprofen Trometamol in Postoperative Endodontic Pain
The purpose of this study is to investigate the analgesic efficacy of multiple doses of Dexketoprofen Trometamol 25 mg on postoperative pain following emergency endodontic treatment in teeth with irreversible pulpitis, using as…
- Trial name
- DTPEP (NCT02086097)
- Testing
- Dexketoprofen trometamol, Ibuprofen
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Total Hip Arthroplasty, Postoperative Pain
Pericapsular Nerve Group (PENG) Block Versus Periarticular Injection for Pain Management After Total Hip Arthroplasty
Adequate pain control after total hip arthroplasty is crucial for early ambulation and patient satisfaction. The pericapsular nerve group (PENG) block has been recently introduced a new technique for blockade of the articular…
- Trial name
- NCT04981236
- Testing
- Pericapsular nerve group block, Periarticular block
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Total Knee Replacement, Post-operative Pain
Tapentadol vs Tramadol in Total Knee Arthroplasty
Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).
- Conditions
- Total Knee Replacement, Post-operative Pain, Chronic Pain
- Trial name
- NCT06269770
- Testing
- Tapentadol, Tramadol
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Thessaly
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\)
Suzetrigine in TKA
Total knee replacements are among the most common and painful orthopedic procedures performed worldwide, often requiring intensive analgesia to support early ambulation and recovery.
- Conditions
- Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\), Total Knee Replacement, Total Knee Replacement Surgery
- Trial name
- NCT07864896
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Intercostal Nerve Cryoablation for Postoperative Pain Management
The purpose of the study is to assess the efficacy of intercostal nerve cryoablation on the magnitude and duration of postoperative pain control both in patients undergoing thoracoabdominal incisions for the descending or…
- Trial name
- NCT03972397
- Testing
- Intercostal Nerve Cryoablation, Bupivacaine liposomal injectable suspension, Patient-controlled analgesia (PCA)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Post Operative Pain, Recurrence
Video-assisted Anal Fistula Treatment Versus Seton in the Management of High Peri Anal Fistula
Anal fistula is the most common Peri anal disease. It's a disease with an incidence of 9 in 100,000. Anal fistula is classified on the basis of its location into high and low anal fistula, above or below dentate line…
- Trial name
- NCT02313597
- Testing
- SETON, VAAFT
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dr. SamiUllah
Postoperative Pain, Lung Cancer
Postoperative Pain Management on Patients Undergoing Lung Tumor Resection
Multimodal analgesia (MMA) is an essential part of Enhanced Recovery After Surgery (ERAS) protocol. The principle of MMA is to manage pain with analgesics of multiple classes acting on distinct target sites through different…
- Conditions
- Postoperative Pain, Lung Cancer, Lung Tumor
- Trial name
- NCT06397807
- Testing
- Dinalbuphine sebacate, Analgesic injectables, Enteral analgesics
- Volunteers
- 400 people
- Sponsor
- China Medical University Hospital
Pain Management After Surgery
Evaluation of the Effect of Virtual Reality Application on Postoperative Pain and Anxiety in Women Aged 50-70
Surgical interventions, while significant milestones in patients\' physical recovery processes, can be a major source of concern for patients due to postoperative pain, which is also an important component of postoperative…
- Trial name
- Pain (NCT06436014)
- Testing
- Providing VR experience
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Osmaniye Korkut Ata University
Failed Back Surgery Syndrome (FBSS)
Caudal Epidural With or Without Lumbar Sympathetic Block for Redo Lumbar Surgery
Comparing the analgesic effect of caudal epidural versus combined lumbar sympathetic block with caudal epidural in patients undergoing redo spinal surgery.
- Trial name
- CLEARS (NCT07199816)
- Testing
- Fluoroscopy-Guided Caudal Epidural Block, Combined Lumbar Sympathetic Ganglion Block and Caudal Epidural Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Hebatullah Mohammed Abdelmageed
Pain
Evaluation of Post-PACU Pain Management in Pediatric Surgery
This study aims to assess the differences in overall pain severity, pain management, and satisfaction during recovery period between two groups of children who either receive or do not receive additional education related to…
- Trial name
- NCT02352116
- Testing
- Additional face-to-face education, Standard of care management
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Columbia University
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Hip Arthroplasty, Total, Postoperative Pain
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Pain After Hip Surgery
Pain after hip replacement surgery is often severe and is commonly treated with opioids, which may cause nausea, vomiting, sedation, difficulty passing urine and slow breathing.
- Conditions
- Hip Arthroplasty, Total, Postoperative Pain, Hip Arthroplasty, Analgesia
- Trial name
- NCT07784192
- Testing
- Morpine, Ultrasound-guided pericapsular nerve group block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Selcuk University
Pain
Could Algometric Assessment be Effective to Adjust Postoperative Analgesic Requirement?
The purpose of this study is to determine the correlation between preoperative algometer score and the amount of postoperative analgesic consumption.
- Trial name
- NCT02375607
- Testing
- Algometer
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Postoperative Pain, Acute Pain
Suzetrigine Versus Standard Analgesia After Skin Cancer Surgery
This randomized clinical trial will compare suzetrigine with standard analgesia for postoperative pain management after skin cancer surgery.
- Conditions
- Postoperative Pain, Acute Pain, Skin Cancer, Cutaneous Malignancy
- Trial name
- NCT07843134
- Testing
- Suzetrigine, Acetaminophen Plus Ibuprofen
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- University of Minnesota
Pain, Postoperative
Pain Management After Surgery
Following outpatient orthopaedic surgery, adequate pain control is imperative both for patient satisfaction and for improved recovery and rehabilitation.
- Trial name
- NCT05154682
- Testing
- OxyCODONE 5 mg Oral Tablet, Acetaminophen 500Mg Tab, Naproxen 500 Mg
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
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