Clinical trials: Post-operative Sensitivity
Tooth Bleaching, Sensitivity, Tooth
Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide
Even with a large number of agents with action desensitizing agents (which reduce the symptoms of tooth sensitivity) available in market, there is no treatment considered the gold standard, which is completely effective for treat…
- Trial name
- NCT06180707
- Testing
- pregabalin gel, gel with 5% potassium nitrate and 2% sodium fluoride
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Post-operative Sensitivity, Dentin Hypersensitivity
Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations
The aim of this study is to compare the effectiveness of Gluma desensitizer in reducing post-operative sensitivity following composite restorations in posterior teeth.
- Conditions
- Post-operative Sensitivity, Dentin Hypersensitivity, Dental Caries, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07188142
- Testing
- Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Beenish Hassan
Pain, Postoperative, Atrial Fibrillation
BRS and Outcomes in Cardiothoracic Surgery
The purpose of this study is to determine whether baroreceptor sensitivity (the ability of your body to change your heart rate and/or blood pressure in response to a situation) has any effect on how likely you are to suffer…
- Conditions
- Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
- Trial name
- NCT03243279
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
URTI, Bronchiolitis
Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms
The purpose of this post-market clinical investigation is to assess in a real-life setting, the effectiveness, usage, tolerance, safety and satisfaction of 4 isotonic and hypertonic seawater-based CE-marked nasal sprays.
- Conditions
- URTI, Bronchiolitis, COVID - 19, Allergic Rhinitis
- Trial name
- SeaBridge (NCT07262450)
- Testing
- Respimer® Hygiene-Prevention -Baby, kids, adults, Respimer® Hygiene-Prevention Kids, adults, Respimer® Decongestion Baby, kids, adults
- Where
- 32 sites in France
- Volunteers
- 1,065 people
- Sponsor
- Laboratoire de la Mer
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Pain, Surgery
The Possible Correlations Between the Genes Related to Pain Sensation and the Pain Sensitivity in the General Population
Objective: This study was conducted to explore the possible correlation between some gene related to pain sensation and individual basal pain perception and postoperative pain intensity in the general population.
- Trial name
- NCT01950078
- Where
- China
- Volunteers
- 1,533 people, healthy volunteers welcome
- Sponsor
- Xianwei Zhang
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital
Lung Carcinoma
Predictive Value of CEA and ctDNA in Lung Cancer Recurrence
The study aims to investigate the predictive value of CEA levels for postoperative recurrence in the highly sensitive CEA lung cancer patients and to explore whether the dynamic changes of postoperative CEA and MRD in this…
- Trial name
- NCT07170046
- Volunteers
- 100 people
- Sponsor
- Guangdong Provincial People's Hospital
Anomaly; Shoulder
Pain Sensitivity and Outcome in Arthroscopic Shoulder Surgery
The purpose of this study is to investigate whether there is a correlation between a patients pain sensitivity and their subsequent post-operative pain and surgical outcome in arthroscopic shoulder surgery.
- Trial name
- PSOASS (NCT01621555)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NHS Fife
Caries,Dental, Sensitivity, Tooth
Post-operative Sensitivity in Resin Composites
This triple-blind, randomized clinical trial was conducted at the department of Operative dentistry. A total of 60 participants were recruited and were randomly distributed into two groups A and B.
- Trial name
- NCT06242184
- Testing
- Group A(Nano-fortified Adhesive), Group B(Adhesive without nanoparticles)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Colon Cancer, Rectal Cancer
Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer
The research objectives is to compare vitro 3D drug sensitivity test results of micro tumor (PTC) with the clinical outcomes of patients, evaluate the consistency between the test results of the technology platform and the…
- Conditions
- Colon Cancer, Rectal Cancer, Chemotherapy Effect, PTC
- Trial name
- NCT05424692
- Testing
- 5-fluorouracil + formyltetrahydrofolate/Oxaliplatin + 5-fluorouracil + formyltetrahydrofolate/Irinotecan + 5-fluorouracil + formyltetrahydrofolate/Cetuximab + 5-fluorouracil + formyltetrahydrofolate
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Pain, Postoperative, Pain Prediction
Venous Cannulation Pain to Guide Choice of Anesthetic Method
The investigators have recently shown that pain associated with peripheral venous cannulation can be used to predict the risk of postoperative pain, where patients grading their pain associated with venous cannulation (VCP) above…
- Conditions
- Pain, Postoperative, Pain Prediction, Laparoscopic Surgery, Venous Cannulation Pain
- Trial name
- NCT04751812
- Testing
- High-pain multimodal anesthesia with opioids, Low-pain opioid free, Standard of care
- Where
- Sweden
- Volunteers
- 270 people
- Sponsor
- Region Halland
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Post-Operative Hypersensitivity
Effects of Rebonding Technique and Final Cure in Post-operative Hypersensitivity in Class 1 Composite Restorations
Rebonding technique has been suggested to address the issue of post-operative hypersensitivity in composite restorations. it involves the application of bonding agent on composite restoration following finishing and polishing.
- Trial name
- NCT07041424
- Testing
- treatment group 1: total etch bonding agent used with rebonding technique, treatment group 2: self etch bonding agent used with rebonding technique
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Foundation University Islamabad
Central Sensitisation, Postoperative Pain
Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery
The study is a prospective observational study designed to determine the effects of central sensitization on pain and functional status of patients before and after total knee joint replacement surgery.
- Conditions
- Central Sensitisation, Postoperative Pain, Arthritis
- Trial name
- NCT06553118
- Testing
- Total knee arthroplasty
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Myocardial Injury After Noncardiac Surgery (MINS), Postoperative Complications
Prediction Model for MINS After Major Hepatobiliary Surgery
This multi-center, prospective observational study aims to develop and validate an interpretable prediction model for Myocardial Injury After Noncardiac Surgery (MINS) in patients undergoing major hepatobiliary surgery.
- Conditions
- Myocardial Injury After Noncardiac Surgery (MINS), Postoperative Complications, Liver Neoplasm, Hepatobiliary Diseases
- Trial name
- NCT07335042
- Testing
- Major Hepatobiliary Surgery
- Where
- 6 sites in China
- Volunteers
- 1,800 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Sensitivity
Efficacy of Desensitizers in Reducing Post-operative Sensitivity Following Composite Restorations
Composite is one of the common aesthetic restorations used in the dentistry. With the advancements in the biomaterials the application of the composites has broadened.
- Trial name
- NCT05024669
- Testing
- Gluma desensitiser, Sheildforce Plus desensitiser, Telio CS desensitiser
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Heart; Dysfunction Postoperative, Cardiac Surgery, Myocardial Infarction
High-sensitivity Troponin in Cardiac Surgery
Among patients undergoing heart surgery, a measurable degree of heart muscle tissue injury is expected. The level of injury can be shown by measuring the blood levels of specific molecules called cardiac biomarkers.
- Conditions
- Heart; Dysfunction Postoperative, Cardiac Surgery, Myocardial Infarction, Myocardial Injury
- Trial name
- NCT01913873
- Testing
- serum concentration changes cardiac biomarkers
- Where
- Belgium
- Volunteers
- 400 people
- Sponsor
- Onze Lieve Vrouw Hospital
Coronary Artery Disease, Anesthesia
Effects of Transcutaneous Acupoint Electrical Stimulation on Postoperative HRV and Hs-cTnT of Elderly With CHD
The aim of this study was to observe the effect of transcutaneous acupoint electrical stimulation (TAES) on postoperative heart rate variability and high-sensitive cardiac troponin T of elderly patients with coronary heart…
- Trial name
- NCT03418194
- Testing
- transcutaneous acupoint electrical stimulation
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Hebei Medical University Third Hospital
Myocardial Infarction (MI), Perioperative Myocardial Injury
High-Sensitivity Troponin T Kinetics and 30-Day Outcomes After Major Abdominal Surgery (TROP-MAS)
Major abdominal surgery (MAS) carries a high risk of 30-day mortality (>5%). Perioperative myocardial injury (PMI) and myocardial injury after noncardiac surgery (MINS) frequently develop asymptomatically due to surgical…
- Conditions
- Myocardial Infarction (MI), Perioperative Myocardial Injury, Sepsis, Digestive System Surgical Procedures
- Trial name
- TROP-MAS (NCT07850492)
- Testing
- High-sensitivity cardiac troponin T (hs-cTnT) surveillance
- Where
- Vietnam
- Volunteers
- 650 people
- Sponsor
- Bach Mai Hospital