Clinical trials: Post-operative Sensitivity
Surgical Site Infection, Beta-lactam Allergy
Prophylactic Antibiotics for Surgical Site Infections and Beta-Lactam Allergy
Postoperative surgical site infection (SSI) is associated with unnecessary use of heath care resources including prolonged hospitalization and increased hospital readmission.
- Trial name
- NCT04401553
- Testing
- cephalosporin, Second tier antibiotic (Vancomycin)
- Sponsor
- University of Texas Southwestern Medical Center
Knee Arthroscopy, Meniscus
Temperature Sensitive Release of PGE2 and Diminished Energy Requirements in Synovial Tissue With Postoperative Cryotherapy - A Prospective Randomised Study After Knee Arthroscopy
Abstract Background: Local external cooling of the postoperative field is a treatment paradigm aiming for enhanced recovery after joint surgery. It is supposed to reduce pain and improve mobilization, enabling same day surgery.
- Conditions
- Knee Arthroscopy, Meniscus, Inflammation, Hydrops
- Trial name
- NCT01247376
- Testing
- Cooling and compression
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Tooth Sensitivity
Effect of Tri Calcium Phosphate on Efficacy and Sensitivity With Vital Tooth Whitening Using 20% Carbamide Peroxide
Teeth sensitivity is the most popular symptom when using At-Home tooth whitening. Tri calcium phosphate containing pastes may affect the efficacy and postoperative sensitivity associated with At-Home vital tooth whitening using…
- Trial name
- NCT03026725
- Testing
- Tri-calcium Phosphate
- Where
- Syria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damascus University
Gastric and Cardia Adenocarcinomas
Biomoleculars Markers of Sensitivity to Pre- and Post-operative Chemotherapy of Gastric and Cardia Adenocarcinomas: a Pilot Study
Some subtypes of gastric and cardia tumors such as adenocarcinoma or gastric linitis with disseminated cells respond poorly to the pre-operative chemotherapy, and some of them do not respond to chemotherapy usually performed.
- Trial name
- NCT02491840
- Testing
- Biopsy
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Postoperative Nausea and Vomiting
Study to Evaluate Anxiety Sensitivity and Somatic Symptoms as Risk Factors for PONV
This prospective observational study aims to evaluate the influence of somatic symptom load and anxiety sensitivity as risk factors for the occurrence of postoperative nausea and vomiting (PONV).
- Trial name
- somPONV (NCT01875120)
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Johannes Gutenberg University Mainz
Dental Pulp Disease, Endodontically Treated Teeth
Post Operative Sensitivity of MTA Obturation
The aim of this study was to investigate the difference in postoperative pain caused by different root canal sealers in patients with irreversible pulpitis symptoms and no apical lesions.
- Conditions
- Dental Pulp Disease, Endodontically Treated Teeth, Endodontic Disease
- Trial name
- NCT06795282
- Testing
- MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Clear Cell Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma
Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
This randomized phase III trial studies carboplatin, paclitaxel and gemcitabine hydrochloride when given together with or without bevacizumab after surgery to see how well it works in treating patients with ovarian, epithelial…
- Conditions
- Clear Cell Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma
- Trial name
- NCT00565851
- Testing
- Bevacizumab, Carboplatin, Docetaxel
- Where
- 709 sites in United States, Japan and 1 more
- Volunteers
- 1,052 people
- Sponsor
- National Cancer Institute (NCI)
Carious Dentin
Postoperative Hypersensitivity and Digital Radiographic Assessment of a Zinc Modified Versus a Conventional Glass Ionomer Cement in Deep Carious Lesion: Randomized Controlled Clinical Trial
The study aim to evaluate the difference between the effect of zinc modified glass ionomer and conventional glass ionomer on the success of partial caries removel technique
- Trial name
- NCT03285022
- Testing
- Partial caries removel techniques
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sepsis
Validation of Progranulin as a Biomarker for Sepsis
Progranulin blood concentrations in patients with sepsis will be analysed in relation to disease status in order to validate progranulin as a biomarker for sepsis. Patients undergoing cardiac surgery will serve as controls.
- Trial name
- PROGRANULIN (NCT03280576)
- Where
- 2 sites in Germany
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Acute Myocardial Infarction, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
High-sensitivity Troponin T in Acute Myocardial Infarction After Cardiac Valvular Surgery
A measurable degree of heart muscle tissue injury is expected in patients undergoing heart valvular surgery. The level of this injury can be measured by cardiac biomarkers in blood samples.
- Conditions
- Acute Myocardial Infarction, Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Myocardial Infarction, Heart Valve Diseases
- Trial name
- NCT02518282
- Testing
- Serum levels of high-sensitivity troponin T, Twelve-lead ECGs, Transthoracic echocardiography (TTE)
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- University of Valladolid
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Restorations, Permanent
Post-operative Sensitivity of a Self-adhesive Restorative Material
Adhesively restoring teeth using a resin-based composite and a modern dental adhesive is now considered a reliable, predictable, and durable procedure.
- Trial name
- NCT05567263
- Testing
- Bulk-fill resin composite, (3M, ESPE), Surefil one™ Self-Adhesive Composite Hybrid
- Where
- Jordan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
NSCLC
Gefitinib for EGFR Sensitive Mutation Postoperative Stage Ib NSCLC Patients
Currently, whether adjuvant therapy should be applied to Stage Ib non-small cell lung cancer (NSCLC) patients who received radical resection remains controversial.
- Trial name
- NCT02526537
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Lunxu Liu
Hypersensitivity Dentin
Post-operative Hyper-sensitivity Assessment After Immediate Versus Delayed Dentine Sealing in Teeth for Indirect Tooth Colored Restorations
PICOT elements:P: Teeth restored with indirect tooth colored restoration I: Immediate dentin sealing using universal adhesive C: Delayed dentin sealing O: Post-operative Hypersensitivity T: -Hypersensitivity assessment one week…
- Trial name
- NCT03562858
- Testing
- Immediate dentin sealing protocol, Delayed dentin sealing protocol
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non-Small Cell Lung Cancer, EGFR Sensitive Mutation
Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations
This multicenter, randomized, controlled, double-blind, double-simulated, Phase III study is designed to evaluate the efficacy and safety of Befotertinib compared with Icotinib as adjuvant treatment in EGFR-sensitive…
- Conditions
- Non-Small Cell Lung Cancer, EGFR Sensitive Mutation, Adjuvant Therapy
- Trial name
- NCT06041776
- Where
- 3 sites in China
- Volunteers
- 570 people
- Sponsor
- Betta Pharmaceuticals Co., Ltd.
Colon Carcinoma
Dipeptide Alanyl Glutamine and Postoperative Insulin Resistance in Colon Carcinoma Patients
Rationale: It is well known that insulin resistance occurs after mediocre and intensive surgery, such as colon cancer surgery. Disturbances in insulin action negatively affect the postoperative recovery, either by prolonging the…
- Trial name
- AIRCo (NCT00922688)
- Testing
- Dipeptide Alanyl-Glutamine
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Medical Center Alkmaar
Chronic Rhinosinusitis With Nasal Polyps, Allergic Fungal Sinusitis
Comparing Budesonide Via MAD or INSI Prospective Cohort Study
Chronic Rhinosinusitis (CRS) is a common disorder in North America, affecting more than 31 million people annually. Common therapy for CRS includes intranasal corticosteroids (INCS) such as budesonide.
- Trial name
- NCT04267042
- Testing
- Budesonide, Mucosal Atomization Device, NeilMed squeeze bottle for Impregnated Nasal Saline Irrigation
- Volunteers
- 60 people
- Sponsor
- St. Paul's Hospital, Canada