Clinical trials: Post-stroke
Stroke
Early Occupational Therapy Intervention in the Hospital Discharge After Stroke
The general objective of this study is to determine if an early occupational therapy (OT) intervention together with the usual care at hospital discharge after suffering a stroke has a positive effect on the quality of life and…
- Trial name
- NCT04835363
- Testing
- Early Occupational Therapy intervention
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- University of Malaga
Acute Ischemic Stroke
Enoxaparin and/or Minocycline in Acute Stroke
The purpose of this study is to investigate whether enoxaparin, minocycline, or both medications in combination may help in recovery from acute stroke.
- Trial name
- NCT00836355
- Testing
- Enoxaparin, Minocycline
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Non-valvular Atrial Fibrillation
WAVECREST Post Market Clinical Follow-Up (PMCF) Study
The WAVECREST PMCF Study is a prospective, non-randomized, multicenter study to confirm safety and performance of the Coherex WaveCrest Left Atrial Appendage (LAA) Occlusion System in the current medical practice setting in…
- Trial name
- NCT03204695
- Testing
- Percutaneous LAA Closure, Anticoagulation or Clopidogrel
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- Coherex Medical
Stroke, Stroke, Ischemic
At-Home taVNS - Stroke Rehab
Early evidence suggests the benefits of post-stroke motor rehabilitation may be enhanced by applying electrical stimulation to the ear.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT06616831
- Testing
- Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Stroke
Effect of Robot Rehabilitation Exercise Training on Motor Control After Stroke
Stroke is a leading cause of neurological disability worldwide, often causing significant weakening and paresis of the affected arm. National spending on post-stroke rehabilitation is project to expand 20% to 35% through 2010.
- Trial name
- NCT02331407
- Testing
- Robotic arm therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Columbia University
Stroke
Efficacy Study of FES Controlled by Electromyographic Signal for the Treatment of Upper Limb in Post-stroke Patients
Goal of the present study is to evaluate the efficacy of Myoelectrically-controlled Functional Electrical Stimulation (MeCFES) for the rehabilitation of upper limb in post-stroke patients.
- Trial name
- RiSES (NCT03019744)
- Testing
- MeCFES-assisted task-oriented upper limb rehabilitation, Usual Care task-oriented upper limb rehabilitation
- Volunteers
- 82 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke
Non-invasive Brain Stimulation (NIBS) and Dual-task Walking After Stroke
The study aims to identify neural locus critical for dual-task walking (walking and talking) in individuals with stroke. To achieve this aim, the investigators apply repetitive transcranial magnetic stimulation (rTMS) to…
- Trial name
- NCT03442868
- Testing
- high frequency rTMS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Texas Woman's University
Post-Stroke Spasticity, Cerebrovascular Accident
Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity
This is a study to confirm the superior efficacy of GSK1358820 over placebo in patients with equinus deformity associated with post-stroke lower limb spasticity using the Modified Ashworth Scale (MAS) ankle score.
- Trial name
- NCT00460655
- Testing
- GSK1358820
- Where
- 20 sites in Japan
- Volunteers
- 120 people
- Sponsor
- GlaxoSmithKline
Strategy Training
Strategy Training for People With Aphasia After Stroke
One-third to one-half of acute strokes result in newly acquired cognitive impairments. Approximately 30 to 40% of people in the acute phase of stroke also sustain communication impairments.
- Trial name
- NCT03593876
- Testing
- Strategy Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Cerebrovascular Accident, Hemiplegia
Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments
The purpose of this study was to determine the effect of two amounts of treatment therapy on post stroke motor recovery in the arms.
- Trial name
- NCT00369668
- Testing
- Bilateral movements and neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Stroke
t-RNS After Hand Recovery in Chronic Stroke
Upper extremity (UE) paresis or weakness is one of the most frequent impairments after stroke. Despite intense rehabilitation, motor and functional recovery of patients with severe hand impairments is poor.
- Trial name
- NCT05489146
- Testing
- transcranial random noise stimulation and functional electrical stimulation facilitated task practice
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Amit Sethi
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
CVA (Cerebrovascular Accident)
Incline Training to Personalize Motor Control Interventions After Stroke
This study will evaluate the use of incline and decline treadmill training to address specific motor control deficits identified within different post-stroke walking patterns.
- Trial name
- NCT03561246
- Testing
- Incline treadmill walking, Decline treadmill walking, Level Treadmill (Control)
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Health Care Acceptability
Telehealth After Stroke Care: Integrated Multidisciplinary Access to Post-stroke Care
The Telehealth After Stroke Care (TASC) trial is a pilot randomized controlled trial. It aims to evaluate the feasibility of a telehealth based model providing multidisciplinary access including nursing, pharmacy and physician…
- Conditions
- Stroke, Health Care Acceptability, Hypertension
- Trial name
- TASC (NCT04640519)
- Testing
- Usual care, TASC intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Atrial Fibrillation
A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation
This is a prospective and open label study that aims to enroll approximately 1200 patients with non-valvular atrial fibrillation (NVAF) not previously treated with Pradaxa® and free of gastrointestinal symptoms (GIS) for at least…
- Trial name
- NCT01493557
- Testing
- pantoprazole, Pradaxa (dabigatran etexilate), Pradaxa, within 30 minutes after a meal
- Where
- 103 sites in United States, Canada
- Volunteers
- 1,067 people
- Sponsor
- Boehringer Ingelheim
Ischemic Symptoms, Cerebral Infarction
Pletaal SR Post Marketing Observational Study
This is a Post Marketing Observational Study of cilostazol (Pletaal® SR capsule). As this study is observational in nature to collect the safety data after administrating the Pletaal SR capsule, from baseline to 16 weeks.
- Trial name
- PLTSRPMOS (NCT01782833)
- Testing
- This is Non-interventional study
- Where
- 4 sites in South Korea
- Volunteers
- 3,635 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Stroke
Effectiveness of Intelligent Rehabilitation Robot Training System Combined With Repetitive Facilitative Exercise on Upper Limb Motor Function After Stroke: a Randomized Control Trial.
The goal of this clinical trial is to learn if intelligent rehabilitation robot training system combined with repetitive facilitative exercise (RFE) work to treat stroke in adults.
- Trial name
- NCT06435624
- Testing
- intelligent robotic-assisted training, repetitive facilitative exercise, conventional therapy
- Where
- China
- Volunteers
- 81 people
- Sponsor
- Nanjing Mingzhou Rehabilitation Hospital
Upper Limb Spasticity
Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity
This is a randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, trial to Evaluate the Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Upper Limb Spasticity in Adults After…
- Trial name
- JUNIPER (NCT03821402)
- Testing
- DAXI for injection 250 U, DAXI for injection 375 U, DAXI for injection 500 U
- Where
- 26 sites in United States
- Volunteers
- 83 people
- Sponsor
- Revance Therapeutics, Inc.
Stroke
Long-term Cardiac Monitoring After Cryptogenic Stroke (CMACS)
Atrial fibrillation (AF) is a common and treatable cause of ischemic stroke, but it can be paroxysmal and asymptomatic, and therefore difficult to detect.
- Trial name
- CMACS (NCT00932425)
- Testing
- Cardionet Mobile Cardiac Outpatient Telemetry (MCOT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Stroke
A Novel Strategy to Decrease Fall Incidence Post-Stroke
Approximately 15,000 Veterans are hospitalized for stroke each year with new cases costing an estimated $111 million for acute inpatient, $75 million for post-acute inpatient, and $88 million for follow-up care over 6 months…
- Trial name
- BLAST (NCT02688777)
- Testing
- Backward Walking Training
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- VA Office of Research and Development