Clinical trials: Post-stroke Arm Spasticity
Stroke, Spasticity as Sequela of Stroke
Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity
Upper extremity splints are one of the nonpharmacologic treatments used to treat hypertonicity after stroke. The purpose of splinting is to support, to position, to immobilize, to prevent contracture and deformities, to reduce…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Upper Limb Hypertonia
- Trial name
- NCT03546959
- Testing
- Lycra sleeve, Rehabilitation, Botulinum Toxin
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Post-Stroke Chronic Upper Limb Spasticity
Effectiveness and Safety of SMART [Spastic Muscle Palpation by Anatomic Landscape for BoNT-A (Botulinumtoxin-A) Injection to Reduce Muscle Tone] BoNT-A Therapy With Dysport® in Patients With Post-stroke Chronic Upper Limb Spasticity (ULS) in Real-life Setting.
The purpose of this study is to collect data for Dysport® SMART BoNT-A therapy usage in an office-based setting in post-stroke participants with chronic (> 6 months) focal Upper Limb Spasticity who have been under stable oral…
- Trial name
- SMART-NIS (NCT05224349)
- Where
- 31 sites in Germany
- Volunteers
- 121 people
- Sponsor
- Ipsen
Post-stroke Spasticity of the Upper Limb
TMS AND BOTULINUM TOXIN IN POST-STROKE UPPER LIMB SPASTICITY
Post-stroke upper limb spasticity is an important condition that negatively affects motor recovery, upper limb functions, and activities of daily living.
- Trial name
- TMS (NCT07624149)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Continuous Theta Burst Stimulation (cTBS)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Asya ÖZCAN KAVCI
Stroke, Cerebrovascular Stroke
The Efficacy of an Acupuncture Protocol and Use of Taping in the Treatment of Spastic Upper Limb After Stroke
The purpose of this study is to determine whether acupuncture and taping are effective in the treatment of spastic upper limb after stroke.
- Trial name
- NCT02690493
- Testing
- Acupuncture, Functional Taping, Acupuncture and Functional Taping
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Fernanda Cechetti
Stroke
Acute Effect of Mirror Therapy on Rehabilitation of Paretic Upper Extremity After Chronic Stroke
Objective: To investigate the acute effect of mirror therapy (MT) on motor control, manual dexterity and spasticity of the paretic upper extremity (UE) of individuals with chronic hemiparesis after stroke, during reaching task.
- Trial name
- NCT03371290
- Testing
- Mirror Therapy, Control Intervention
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Post Stroke Arm Spasticity
Study to Document the Effectiveness of Dysport in Patients Suffering From Upper Limb Spasticity (ULS) After Stroke
The objective of this non-interventional study is to evaluate clinical effectiveness and cost effectiveness of Dysport within the reimbursement scheme called "drug programme" funded by Polish National Health Fund (NHF) for…
- Trial name
- PSAS REGISTRY (NCT02444494)
- Where
- 6 sites in Poland
- Volunteers
- 108 people
- Sponsor
- Ipsen
Upper Limb Spasticity
Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity
This is a randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, trial to Evaluate the Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Upper Limb Spasticity in Adults After…
- Trial name
- JUNIPER (NCT03821402)
- Testing
- DAXI for injection 250 U, DAXI for injection 375 U, DAXI for injection 500 U
- Where
- 26 sites in United States
- Volunteers
- 83 people
- Sponsor
- Revance Therapeutics, Inc.
Cerebrovascular Accident
A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subjects With Post-stroke Upper Limb Spasticity
This is a multicenter, double-blind, randomized, placebo-controlled study designed to compare Botulinum Toxin Type A for Injection (HengLi®) with placebo on the efficacy and safety of treatment in post-stroke subjects with focal…
- Trial name
- NCT02280083
- Testing
- Botulinum Toxin Type A for Injection
- Volunteers
- 180 people
- Sponsor
- Lanzhou Institute of Biological Products Co., Ltd
Stroke, Hemiplegia
Functional Outcome of Hemiplegic Upper Extremity in Patients With Subacute Stroke After Kinesiotaping and Rehabilitation
1. To explore the role of sonoelastography with shear wave velocity to assess poststroke spasticity of affected arm and forearm muscles in patients with stroke. 2.
- Trial name
- NCT04027985
- Testing
- Kinesiotaping, Hand rehabilitation program
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Muscle Spasticity
Early Use of Botulinum Toxin in Spasticity Post Stroke.
Patients who survive a stroke are often left with an arm that cannot be used. One reason for this is that the muscles affected by the stroke become overactive. This is known as spasticity.
- Conditions
- Stroke, Muscle Spasticity, Contracture
- Trial name
- EUBoSS (NCT01882556)
- Testing
- onabotulinumtoxinA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Arm Spasticity
Comparing Lower-concentration Dysport Treatment Targeted to the Neuromuscular Junction With Current Clinical Practice
The aim of the study was to compare Dysport treatment results (as assessed by Modified Ashworth Scale (MAS) in the elbow joint 4 weeks post treatment) following two treatment techniques: the current clinical practice injection…
- Trial name
- NMJ (NCT01682148)
- Testing
- Botulinum toxin type A
- Where
- 23 sites in Denmark, Finland and 2 more
- Volunteers
- 100 people
- Sponsor
- Ipsen
Upper Limb Spasticity
Efficacy and Safety Study of Botulinum Neurotoxin A With Rehabilitation Versus Botulinum Neurotoxin A Alone in Treatment of Post-stroke Spasticity
The purpose of this study is to determine if a combination of botulinum neurotoxin A and rehabilitation therapy is better than botulinum neurotoxin A alone for improvement in function based on the Fugl-Meyer and other validated…
- Trial name
- NCT00945295
- Testing
- Botulinum toxin type A, BoNT-A, Rehabilitation Therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- JoAnn Harnar
Cerebrovascular Disorders, Spasticity, Muscle
The Effect of Ultrasound-Guided Botulinum Toxin Injections on Pain, Functionality, Spasticity, and Range of Motion in Patients With Post-Stroke Upper Extremity Spasticity
The patients between the ages of 35-80 who developed spasticity in the upper extremity after stroke will be included.. Botulinum toxin(BT-A) injection will be applied to the study group(n=16) and placebo injection to the control…
- Conditions
- Cerebrovascular Disorders, Spasticity, Muscle, Botulinum Toxin
- Trial name
- NCT05887479
- Testing
- Botulinum toxin type A, %0,9 NaCl
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Upper Limb Spasticity
BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity
In this study, we will compare BOTOX® versus Zanaflex ® for the treatment of muscle overactivity in the upper limb following stroke or brain traums.
- Trial name
- NCT00430196
- Testing
- BOTOX®, Zanaflex®
- Volunteers
- 135 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke, Upper Extremity Dysfunction
REHABOTICS: Physiotherapy for Hand Spasticity After Stroke Using Robotics and AR Serious Games
Rehabotics is a comprehensive rehabilitation system designed to deliver individualized upper-limb therapy for patients with motor impairments, particularly after stroke.
- Conditions
- Stroke, Upper Extremity Dysfunction, Spasticity Post Stroke
- Trial name
- NCT07468149
- Testing
- Rehabotics Physiotherapy
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Pantelis Syringas
Hemiplegia, Spastic
Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity
The reliability of the Australian Spasticity Assessment Scale (ASAS) has been reported to be not high enough in adult patients with acquired brain damage.
- Trial name
- NCT04613661
- Testing
- Australian Spasticity Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Izmir Katip Celebi University
Stroke, Spasticity
Phase III Study of Botulax® to Treat Post Stroke Upper Limb Spasticity
The purpose of this study is to evaluate the safety and efficacy of Botulax® compared to Botox® reducing upper limb muscle tone in post stroke patients.
- Trial name
- NCT01915459
- Testing
- Botulinum toxin type A(Botulax®), Botulinum toxin type A(Botox®)
- Where
- 6 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Hugel
Muscle Spasticity
CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase1)
The purpose of this study is to evaluate the safety and pharmacodynamic of CORETOX® in the treatment of post-stroke upper limb spasticity
- Trial name
- NCT05164003
- Testing
- CORETOX®, BOTOX®
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Medy-Tox
Post-stroke Upper Limb Spasticity
Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
The general objective of this study was to evaluate the efficacy of the comprehensive protocol in improving post-stroke upper limb spasticity.
- Trial name
- NCT05940805
- Testing
- Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Post-Stroke Spasticity
A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)
The goal of this clinical trial is to learn if the drug BMS-986368 works to treat post stroke spasticity in adults who have had a stroke.
- Trial name
- STIPS (NCT07704840)
- Testing
- Administration of BMS-986368
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Alberto Esquenazi