Clinical trials: Post-stroke Depression, open to volunteers
Apathy, Stroke
Accelerated rTMS vs. Sham for Stroke Apathy
Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them.
- Conditions
- Apathy, Stroke, Stroke Sequelae, Stroke/Brain Attack
- Trial name
- NCT07113067
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active), Brainsight Neuronavigation System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Post Stroke Depression
Allopregnanolone (Zuranolone) in Post-stroke Depression
The goal of this Phase II clinical trial is to learn if the oral synthetic allopreganolone analog (zuranolone) is safe to take and is well tolerated by stroke survivors experiencing moderate to severe post-stroke depression and…
- Trial name
- ALLO in PSD (NCT06759558)
- Testing
- Zuranolone
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Stroke, Post-stroke Depression
Effects of Robotic Rehabilitation on Quality of Life, Mood, and Fatigue After Stroke
Stroke is a major cause of long-term disability and is often associated with reduced quality of life, depression, anxiety, and fatigue.
- Conditions
- Stroke, Post-stroke Depression, Post-stroke Anxiety, Post-stroke Fatigue
- Trial name
- NCT07203937
- Testing
- RoboGait® Robotic Gait Training, Treadmill Walking Training
- Volunteers
- 36 people
- Sponsor
- Meltem Gunes Akinci
Post Stroke Depression
Hyperbaric Oxygen Therapy for Persistent Post Stroke Depression
The study evaluates the effect of HBOT on depression in patients suffering from persistent symptoms of post stroke depression (PSD) in an double blind sham control study.
- Trial name
- NCT07423273
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 142 people
- Sponsor
- Assaf-Harofeh Medical Center
Stroke, Post-stroke Depression
Physical Capacity Building for Chronic Stroke
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery.
- Trial name
- NCT07039305
- Testing
- Physical capacity training for chronic stroke - building aerobic capacity and muscle strength
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
Post-stroke Depression, Subthreshold Depression
Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors
The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke…
- Trial name
- LIVE-WEL (NCT06864715)
- Testing
- Tele-delivered Behavioral Activation by lay counselors after Stroke (Tele-BA-S), Treatment as Usual
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- The University of Texas Health Science Center, Houston
Post-stroke Depression
A Study on the Preventive Effect of Electroacupuncture Combined With Dexmedetomidine in Post-stroke Depression
Post-stroke depression (PSD) is a common neuropsychiatric complication following stroke and has emerged as a major public health concern due to its adverse impact on post-stroke prognosis.
- Trial name
- NCT07739329
- Testing
- Dexmedetomidine, Electropuncture, Normal Saline (NS)
- Volunteers
- 231 people
- Sponsor
- Min Su
Stroke, Post Stroke Depression
A Study on the Application of Positive Psychological Counseling Based on "Dou Bao" Software in Patients With Post-stroke Depression
Patients with PSD have the characteristics of high incidence rate, difficult identification and great harm. However, the existing AI chat platforms have not developed any relevant software or programs for PSD patients.
- Trial name
- NCT07336888
- Testing
- The positive psychological counseling platform of the "Doubao" software
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Post Stroke Depression, Post Stroke Fatigue
The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation.
Background: Light is the most important regulator of circadian rhythm. Naturalistic light, which contains the spectrum of sunlight throughout the day, has been shown to have a positive impact on mental states such as depression…
- Conditions
- Post Stroke Depression, Post Stroke Fatigue, Circadian Dysregulation, Stroke
- Trial name
- NCT06922409
- Testing
- Naturalistic Light Intervention
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Post-stroke Depression
Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke
Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive…
- Trial name
- NCT07294274
- Testing
- Group patients based on whether they have been diagnosed with PSD.
- Where
- China
- Volunteers
- 488 people
- Sponsor
- Min Su
Stroke, Post Stroke
An Ecological Momentary Assessment Based Program to Support Self-Management for Post-stroke Patients
The goal of this feasibility study is to test whether a new approach that combines real-time symptom tracking (Ecological Momentary Assessment) with machine learning can help people recovering from a stroke to better manage…
- Trial name
- NCT07691411
- Testing
- Ecological Momentary Assessment based Self-management Program
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
CVA (Cerebrovascular Accident), Ictus
Music Therapy in Post-Stroke Patients: A Clinical Trial
The goal of this clinical trial is to learn if music therapy works to optimizate sleep quality in patients who have suffered a stroke.
- Conditions
- CVA (Cerebrovascular Accident), Ictus, Stroke Acute, Insomnia
- Trial name
- NCT07899034
- Testing
- Music therapy
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Universidad de Granada
Cerebral Apoplexy, Depression Anxiety Disorder
Efficacy and Safety Evaluation of Remote Ischemic Adaptation ( Intermittent Pressure Stimulation ) in the Treatment of Insomnia After Stroke
The incidence of post-stroke depression is high, which will affect the rehabilitation of neurological function, damage cognitive function, and increase the risk of subsequent stroke recurrence.
- Conditions
- Cerebral Apoplexy, Depression Anxiety Disorder, Cerebrovascular Disease
- Trial name
- NCT07401784
- Testing
- Automatic ischemic preconditioning therapeutic apparatus
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Post-stroke Depression, Remote Ischemic Conditioning
Efficacy of Remote Ischemic Conditioning in Preventing Post-Stroke Depression
Post-stroke depression (PSD) is characterized primarily by low mood and loss of interest following a stroke. It is one of the most common and serious complications of stroke, with an incidence of 11% to 41% within two years…
- Trial name
- NCT06920706
- Testing
- RIC
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Post-stroke Depression
Investigating How the RECT Impacts Brain Functional States Through the ACC-cerebellar Loop
Experiment1: Using a brain EEG-TMS combined system, researchers aim to investigate the impact of the rostral anterior cingulate cortexr (rACC)-engaging cognitive task (RECT) combined single-pulse TMS magnetic stimulation on theta…
- Trial name
- NCT06912191
- Testing
- Left cerebellar TMS stimulation combined with the RECT task, Right cerebellar TMS stimulation combined with the RECT task, Midline cerebellar TMS stimulation combined with the RECT task
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stroke, Stress, Psychological
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
Outpatient participants with a recent stroke diagnoses receive complimentary rehabilitation. The nature interventions include ergo- and physiotherapeutic and neurocognitive tasks with the support of an psychotherapeutic frame…
- Conditions
- Stroke, Stress, Psychological, Post Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06633146
- Testing
- Therapies in nature
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Stroke, Post-stroke Depression
The Research Team Aims to Elucidate the Impact of ITBS (intermittent Theta Burst Stimulation) on the HPA Axis and Post-stroke Negative Emotions/depression by Conducting Human Experiments That Target Various Brain Regions.
The project team will categorize stroke patients into three groups receiving iTBS stimulation targeting distinct brain regions: the cerebellum, the dorsolateral prefrontal cortex (DLPFC), and the primary motor cortex (M1), with…
- Trial name
- NCT06899893
- Testing
- iTBS
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University