Clinical trials: Post-surgical Pain
Postoperative Pain
Clinical Analysis of Pain After Hysterectomy
Patients undergone either laparoscopic or vaginal hysterectomy will called for a clinical examination 1-3 years after surgery, if they suffer from pain 6 months after surgery. The aims of the study are: 1.
- Trial name
- NCT01706549
- Where
- Finland
- Volunteers
- 16 people
- Sponsor
- Tampere University Hospital
Postoperative Pain, Inflammation
Effect of Oral Choline Supplementation on Postoperative Pain
This research will test whether consuming additional choline before gynecological surgery decreases postoperative pain.
- Trial name
- NCT00720343
- Testing
- Choline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Postoperative Pain
Patient Controlled Analgesia Pump Cues on Patient Satisfaction
To examine whether providing patients with a cue to the availability of pain medication affects patient satisfaction, patient anxiety, PCA efficacy, and safety.
- Trial name
- PCA Cues (NCT02456909)
- Testing
- Patient-Controlled Analgesia pump with Cues, Patient-Controlled Analgesia pump without Cues, Morphine
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Medical College of Wisconsin
Bariatric Surgical Pain
Intraoperative Lidocaine Infusion for Postoperative Pain Management in Obese Patients
The primary objective is to assess the feasibility and safety of administering continuous intraoperative lidocaine infusions in adult patients undergoing laparoscopic Roux en Y Gastric Bypass (RYGB).
- Trial name
- NCT01944098
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of South Florida
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Postsurgical Pain
Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
- Trial name
- NCT04774328
- Testing
- CA-008 (vocacapsaicin)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Concentric Analgesics
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Total Knee Replacement Surgery
Adductor Canal Catheter Effectiveness and Safety Study
PRIMARY OBJECTIVE: Compare the effect of usual care with an adductor canal catheter (ACC) containing ropivacaine to the effect of usual care without an ACC on the second-postoperative-day pain levels among patients undergoing…
- Trial name
- ACCESS (NCT04639128)
- Testing
- Adductor Canal Catheter
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Kaiser Permanente
Postoperative Pain
Dose Finding Posterolateral Thoracotomy Study
To review safety and effectiveness of two doses compared to current standard of care.
- Trial name
- NCT00807209
- Testing
- Low Dose SKY0402, High Dose SKY0402, Fentanyl via PCA
- Where
- 5 sites in United States
- Volunteers
- 3 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Post Surgical Pain
Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%
When used in conjunction with a local anesthetic, dexamethasone may prolong both the sensory and motor effects of high supraclavicular brachial plexus nerve block (SBP) in arthroscopic shoulder surgery.
- Trial name
- Dex Dose (NCT01690663)
- Testing
- Bupivacaine 0.25%, Dexamethasone, normal saline
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Pennsylvania
Pain, Postoperative, Burns
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
Donor site pain study comparing post-operative donor site pain and opioid consumption after use of Lidocaine, Liposomal Bupivicaine or regional nerve block for split thickness skin graft harvesting in patients with less than 20%…
- Trial name
- NCT03854344
- Testing
- Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Kansas Medical Center
Hallux Valgus
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
The purpose of this study is to evaluate the analgesic efficacy and safety of tapentadol immediate-release (IR [CG5503]) for use in the relief of moderate to severe acute pain, compared with placebo, in adult Taiwanese patients…
- Trial name
- NCT01813890
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Janssen-Cilag International NV
Post Operative Pain
Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine
This study aims to compare the effect of pre-operative oral pregabalin on post operative morphine consumption after abdominal hysterectomy with/without salpingo-oophorectomy.
- Trial name
- NCT02285010
- Testing
- Pregabalin
- Where
- Thailand
- Volunteers
- 125 people
- Sponsor
- Mahidol University
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Pain, Postoperative, Hysterectomy
Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy
The purpose of this study is to evaluate the effect of using ice packs on the abdomen immediately after laparoscopic hysterectomy surgery on pain control and narcotic pain medication use.
- Conditions
- Pain, Postoperative, Hysterectomy, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT03341533
- Testing
- Ice packs plus usual post-op analgesia, Usual post-op analgesia
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Mayo Clinic
Postoperative Pain, Knee Replacement Arthroplasty
Management of Postoperative Pain After Total Knee Replacement.
The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.
- Trial name
- NCT01163214
- Testing
- Nerve Block, Periarticular Injection
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Mark J. Spangehl, M.D.
Pain, Post-operative
Evaluation of N1539 Following Bunionectomy Surgery
The primary objective of this study is to evaluate the analgesic efficacy of N1539 in subjects with acute moderate to severe pain following unilateral bunionectomy.
- Trial name
- NCT02675907
- Testing
- N1539
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Baudax Bio
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Bariatric Surgery
The purpose of this prospective, blinded, randomized clinical trial is to investigate whether a ventilator-piloted PRM at the end of laparoscopic bariatric surgery could reduce overall postoperative pain and nausea.
- Trial name
- NCT03026530
- Testing
- Pulmonary recruitment maneuver, Laparoscopic bariatric surgery, Ventilator
- Volunteers
- 200 people
- Sponsor
- Region Östergötland
Postoperative Pain
A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Undergoing Total Knee Arthroplasty
The primary objective is to demonstrate that SKY0402 is superior when compared to bupivacaine HCl in the management of postoperative pain for patients undergoing total knee arthroplasty.
- Trial name
- TKA (NCT00745290)
- Testing
- Bupivacaine HCl, SKY0402
- Where
- 19 sites in United States
- Volunteers
- 245 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postoperative Pain
Ultrasound Guided Distal Peripheral Nerve Blocks and Postoperative Pain.
The aim of this clinical trial is to determinate if distal ultrasound guided peripheral nerve blocks on target nerves (radial and median nerve blocks at the elbow), using low volume and low concentration of long acting local…
- Trial name
- NCT01597479
- Testing
- Levobupivacaine
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau