Clinical trials: Post-traumatic
Mental Disorder, Substance Use Disorders
Supported Employment in Patient Aligned Care Teams
In response to the Rehabilitation Research and Development (RR\&D) Deployment Health Research, this study addresses the delivery of an evidenced-based vocational rehabilitation, specifically Individual Placement and Support…
- Conditions
- Mental Disorder, Substance Use Disorders, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT02400736
- Testing
- Individual Placement and Support (IPS), Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury
BLOOD BIOMARKERS in PAEDIATRIC MTBI
The goal of this observational study is to identify blood biomarkers that could help in the management of paediatric patients with mild TBI. The main questions it aims to answer are: 1.
- Trial name
- t-BIOMAP (NCT06233851)
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Pediatric Clinical Research Platform
Post-traumatic Stress Disorder (PTSD), Emotional Contagion
Attachment and Post-Traumatic Stress Disorder in Military Personnel: Characterization of the French Military Population, Exploration of Biopsychosocial Factors, and Study of the Impact of Security Priming on Emotional Contagion Capacities
Post-traumatic stress disorder (PTSD) is a pathology that impairs the quality of life of sufferers. In military personnel, it can lead to military incapacity.
- Trial name
- AT-HOME (NCT06996275)
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Mental Health Issue, Mental Stress
Evaluating Implementation and Impact of PeerOnCall, a Mobile Health Approach to Peer Support for Canadian Public Safety Personnel
A prospective cohort study design will be implemented across four sectors and multiple organizations sites to evaluate implementation and impact of the apps.
- Conditions
- Mental Health Issue, Mental Stress, Post Traumatic Stress Disorder
- Trial name
- NCT05429619
- Testing
- PeerOnCall
- Where
- 3 sites in Canada
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- McMaster University
Posttraumatic Stress Disorder
Reducing Reconsolidation of Trauma Memories With Propranolol
The purpose of this study is to test whether propranolol is capable of reducing subsequent physiological trauma-related conditioned responses, as well as self-reported post-traumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT01349439
- Testing
- Propranolol, Short acting + long acting propranolol + memory reactivation
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Douglas Mental Health University Institute
Brain Concussion, Post-Concussion Syndrome
Early Intervention Programme for Young Patients (Aged 15 - 30 Years) With Symptoms Following Concussion.
Background: Five - 15 % of patients with concussion continue to experience impairing physical, cognitive and emotional symptoms longer than 3 months post-injury.
- Trial name
- NCT02337101
- Testing
- Enhanced Usual Care (EUC), EUC + Early intervention programme
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Bulbocavernosus Reflex, Spinal Cord Injuries
Evaluation of the Bulbocavernosus Reflex After Acute Spinal Cord Injury
The purpose of this study is to evaluate the possibility to use electromyography in acute phase after a traumatic spinal cord injury to measure quantitatively and objectively the bulbocavernosus reflex.
- Trial name
- NCT04316195
- Testing
- Assessment of the bulbocavernosus reflex
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Andréane Richard-Denis
Effect of Physiotherapy on Cobb Angle in Patients With Cervicogenic Headache
Effect of Myofascial Release Technique Alone or Combined With Exercises on Cervical Cobb Angle, Sleep Quality, and Psychological Factors in Patients With Cervicogenic Headache
This study will investigate whether myofascial release therapy alone or in combination with therapeutic exercises can improve cervical spine alignment, measured by cervical Cobb angle on X-ray, in patients with cervicogenic…
- Trial name
- NCT07168512
- Testing
- Exercises (Endurance and strengthening), Myofascial release technique
- Where
- 3 sites in Palestinian Territories
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
PTSD, Alcohol Use Disorder
Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder
For this protocol, the investigators plan to collect pilot data to: 1. establish the feasibility and safety of administering brexanolone to individuals with concurrent Posttraumatic Stress Disorder (PTSD) and Alcohol Use Disorder…
- Trial name
- NCT05223829
- Testing
- Brexanolone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Yale University
Mild Traumatic Brain Injury
Balance and Mild Traumatic Brain Injury: The Effect of a Weighted Compression Vest
After a mild traumatic brain injury (mTBI) people often report balance problems. At Parkwood hospital we have noticed that balance is improved when patients with mTBI wear a weighted compression vest.
- Trial name
- NCT02084329
- Testing
- Weighted Compression Vest
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stress Disorders, Post-Traumatic
Post Traumatic Stress Among Relatives of Brain-dead, Withdrawal of Life Support, and Sudden Death Patients
This study concerns the nearest relatives of patients who have passed away within 3 days of admission to an ICU due to: (1) brain death with multiple organ donation +/- tissues or (2) death via limitation and / or cessation of…
- Trial name
- NCT01412502
- Testing
- IES-R and HDAS scores
- Where
- 6 sites in France
- Volunteers
- 119 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stress Disorders, Post-Traumatic
Prevention of Postpartum Traumatic Stress (PTSD) in Mothers With Preterm Infants.
The purpose of the study includes: 1. To develop a treatment manual and pilot test this treatment intervention which is designed to prevent and reduce psychological distress in parents who have infants hospitalized in the…
- Trial name
- NCT01307293
- Testing
- Cognitive behavior therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Stanford University
Rehabilitation After Neurological or Orthopaedic Injuries
Feasibility of Unsupervised Therapy After Neurological or Orthopaedical Injury in the Home Setting With a Hand Rehabilitation Device (ReHandyBot) and an Assistive Smartphone Application (RehabCoach)
The goal of this clinical trial is to evaluate whether using the ReHandyBot hand rehabilitation device together with the RehabCoach smartphone app can support safe, independent, and effective home therapy in patients with stroke…
- Trial name
- NCT07182734
- Testing
- Supervised and minimally-supervised therapy with ReHandyBot and RehabCoach, Unsupervised Therapy with ReHandyBot and RehabCoach
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
Post Traumatic Stress Disorder
Islamic Trauma Healing: Feasibility Study
This study will examine the initial feasibility of a program called Islamic Trauma Healing by conducting a small feasibility study (N = 26) of Islamic Trauma Healing in Somalia on key targets of PTSD, depression, somatic…
- Trial name
- NCT03761732
- Testing
- Islamic Trauma Healing
- Where
- 2 sites in Somalia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Washington
Post-Traumatic Stress Disorders
Treatment of NLP Method in Women Who Have Experienced Postpartum Post Traumatic Stress Dissorder
The purpose of this interventional study is to evaluate the effectiveness of the NLP PTSD protocol in the event of PPPTSD. The study's main hypothesis is that the implementation of the NLP protocol will be effective and result in…
- Trial name
- NLP (NCT02730806)
- Testing
- NLP
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yfat Weinstein-Zohar
Post Traumatic Stress Disorder
Hair Cortisol Level as a Predictor of PTSD Development
Post-traumatic stress disorder, PTSD, is one of the most prevalent psychiatric disorders. As casualties of motor vehicle accidents, criminal acts or terrorism are arriving to the ER, it is almost impossible to conclude who will…
- Trial name
- NCT01804426
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Posttraumatic Stress Disorder, PTSD
Efficacy of 60-minute Versus 90-minute Sessions in Treating PTSD Using Prolonged Exposure
The purpose of this study is to determine whether 60-minute sessions of prolonged exposure (PE) are as effective as the standard 90-minute session for treating posttraumatic stress disorder (PTSD).
- Trial name
- NCT01911585
- Testing
- Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Pennsylvania
PTSD
Post-Traumatic Stress Disorder (PTSD) Symptom Study
The primary goals for this investigation are to quantify: (1) fluctuations in PTSD symptom reports when assessed at bi-weekly intervals; (2) change in PTSD symptoms associated with stressful life events; and (3) change in PTSD…
- Trial name
- NCT00018798
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
This is a pilot randomized controlled trial to assess the impact of a first-line treatment for posttraumatic stress disorder (PTSD) (Cognitive Processing Therapy; CPT) versus waitlist control on mechanisms of cardiovascular…
- Trial name
- NCT06429293
- Testing
- Cognitive processing therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Arthritis, Traumatic Arthritis
The Medacta International GMK Sphere Cementless Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance study of GMK Sphere cementless knee prosthesis.
- Conditions
- Arthritis, Traumatic Arthritis, Rheumatoid Arthritis, Poly-arthritis
- Trial name
- NCT05003414
- Testing
- GMK Sphere cementless Knee Replacement
- Where
- 5 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
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