Clinical trials: Post-traumatic
PTSD
TIMBER Psychotherapy and Ketamine Single Infusion in Chronic PTSD
Background: The poor prognosis and public health burden of PTSD necessitates the development of more effective and broader treatment approaches.
- Trial name
- NCT02766192
- Testing
- Ketamine, TIMBER Psychotherapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cooper Health System
PTSD, Post Traumatic Stress Disorder
Targeted Plasticity Therapy for PTSD
Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared…
- Trial name
- NCT06266364
- Testing
- Active VNS stimulation
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
Posttraumatic Stress Disorder, Shame
NET for SGBV Survivors in Eastern DR Congo
Throughout the last 10 years Narrative Exposure Therapy (NET) has evolved as one of the most effective, culturally sensitive trauma interventions.
- Trial name
- NCT02989987
- Testing
- Narrative Exposure Therapy, Social Support
- Where
- Germany
- Volunteers
- 201 people
- Sponsor
- University of Konstanz
Burns, Scar Pruritus
Exploring the Correlation Between Post Traumatic Stress Disorder, Perceived Stress and Scar Pruritus in Burn Patients
Pruritus, post traumatic stress disorder and perceived stress are common issues in burn patients. The correlation between the three is unclear so far.
- Conditions
- Burns, Scar Pruritus, Post Traumatic Stress Disorder, Perceived Stress
- Trial name
- NCT05885321
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- National Taiwan University Hospital
IBS - Irritable Bowel Syndrome, Constipation
Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders
The purpose of this study is study bowel symptoms, quality of life, and personal factors that may affect your health. In Aim 1 of this study participants will be invited to complete 6 survey-based questionnaires online.
- Trial name
- PTSD (NCT04060121)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Indiana University
Avascular Necrosis of Hip, Osteoarthritis, Hip
Allofit® IT Ceramic Bearing System in Total Hip Arthroplasty
This is a multi-center, prospective, non-controlled post market surveillance study. The objectives of this study are to obtain survival and outcome data on the Allofit IT Shell in combination with the BIOLOX® delta Taper Liner…
- Conditions
- Avascular Necrosis of Hip, Osteoarthritis, Hip, Inflammatory Arthritis, Post-Traumatic Osteoarthritis of Hip
- Trial name
- NCT03672916
- Where
- 4 sites in Germany, Sweden
- Volunteers
- 185 people
- Sponsor
- Zimmer Biomet
Posttraumatic Stress Disorder (PTSD), Insomnia
Yoga Nidra for Insomnia and Posttraumatic Stress Symptoms
This randomized feasibility study is designed to investigate the feasibility of recruitment and delivery of two variations (brief; full) of a virtual Integrative Restoration (iRest) yoga nidra meditation intervention in stressor…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Insomnia, Stressor, Psychological, Psychological Trauma
- Trial name
- NCT06888336
- Testing
- Yoga nidra (full), Yoga nidra (brief)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University College, London
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Biological Signatures, Probiotic Among Those With mTBI and PTSD
Exaggerated inflammation in the body and brain is thought to play a role in the vulnerability to and aggravation and perpetuation of adverse consequences among those with co-occurring mild TBI (mTBI) and post-traumatic stress…
- Trial name
- NCT02723344
- Testing
- of Lactobacillus reuteri (L. reuteri; DSM 17938), Sunflower and medium chain triglyceride oils
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
Prevention of Postpartum Traumatic Stress (PTSD) in Mothers With Preterm Infants.
The purpose of the study includes: 1. To develop a treatment manual and pilot test this treatment intervention which is designed to prevent and reduce psychological distress in parents who have infants hospitalized in the…
- Trial name
- NCT01307293
- Testing
- Cognitive behavior therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Stanford University
Brain Concussion
Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion
Previous research and position statements have outlined the necessity of balance and gait testing in the post-concussion evaluation of athletes.
- Trial name
- NCT02317107
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders
Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders
This study explores whether participating in an 8-week Brazilian Jiu-Jitsu (BJJ) program is linked to changes in trauma-related symptoms among first responders.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties
- Trial name
- CAM-GRIP (NCT07783516)
- Testing
- Brazilian Jiu-Jitsu Program
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Anxiety, Depression
A Mobile Health Solution for Homework During CBT
The purpose of this study is to preliminarily evaluate a web-based app to improve provider implementation and patient engagement in homework (i.e., between-session practice of skills learned during therapy) during child mental…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04931199
- Testing
- Cognitive Behavioral Therapy (CBT), CBT+App
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of South Florida
Sexual Violence, Posttraumatic Stress Disorder (PTSD)
Testing STAR and TextSTAR: A Randomized Controlled Trial
The goal of this clinical trial is to learn whether a video given for recent sexual assault survivors and/or a 3-week text messaging intervention with similar content is effective at reducing mental health problems and substance…
- Conditions
- Sexual Violence, Posttraumatic Stress Disorder (PTSD), Opioid Misuse
- Trial name
- NCT07630428
- Testing
- Skills Training in Active Recovery (STAR) Video, Text Skills Training in Active Recovery (TextSTAR) program
- Where
- 3 sites in United States
- Volunteers
- 394 people
- Sponsor
- University of Wisconsin, Madison
PTSD, Insomnia, Secondary
Written Exposure Therapy and App-Delivered Mindfulness Meditation for PTSD in China: A Pilot Study
The goal of this study is to use a pilot RCT to assess the effectiveness of Written Exposure Therapy (WET) and a mindfulness-based app (MBA) for managing PTSD and comorbid insomnia in China.
- Trial name
- NCT06394700
- Testing
- written exposure therapy, Written Exposure Therapy plus Mindfulness-Based App (WET + MBA), Minimal Contact Control (MCC)
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Peking University
Posttraumatic Stress Disorder, Panic Disorder
Study of Brain Circuitry in Anxiety Disorders
A diverse body of research has implicated the amygdalo-cortical circuitry in the pathophysiology of anxiety disorders. For example, one model of PTSD posits exaggerated amygdala responsivity to threat-related stimuli as well as…
- Conditions
- Posttraumatic Stress Disorder, Panic Disorder, Specific Phobias
- Trial name
- NCT01849432
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Type 1 Diabetes
Prevalence of Post Traumatic Stress Disorder Related to Diabetes Diagnosis or Severe Hypoglycaemia in Adult With Type 1 Diabetes
In France, the adult population living with diabetes in 2016 is estimated at more than 3.3 million patients treated. Type 1 diabetes (T1DM) represents 5.6% of diabetic patients (approximately 185,000 patients).
- Trial name
- NCT05662657
- Testing
- Diagnostic Test: PCL-S Questionnaire
- Where
- 2 sites in France
- Volunteers
- 297 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Major Depression, Post-Traumatic Stress Disorder
Expanding and Testing VA Collaborative Care Models for Depression
Based on the published evidence, collaborative care for depression is both necessary and sufficient for improving care and outcomes for depressed patients in primary care settings.
- Trial name
- ReTIDES (NCT00119028)
- Testing
- Depression Care Quality Improvement Implementation
- Where
- 6 sites in United States
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder, Traumatic Brain Injury
Therapeutic Horsemanship in Veterans
The project partnered with U.S. military veterans with a premier accredited therapeutic riding center for six weeks. The veterans interacted with horses by grooming and learning about them, as well as riding them for one hour per…
- Trial name
- NCT02891421
- Testing
- Therapeutic Horseback Riding, Standard Care
- Volunteers
- 38 people
- Sponsor
- University of Missouri-Columbia
Acquired Bleeding Disorder, Trauma
Incidence/Magnitude-Haemorrhagic Progression-Cerebral Contusions and Identification (ID) of Safety Issues After Traumatic Brain Injury
This study is conducted in North America. The purpose of this study is to evaluate the occurrence and severity of bleeding in brain injury and to identify important safety issues following traumatic brain injury.
- Trial name
- NCT00124293
- Testing
- activated recombinant human factor VII
- Where
- 2 sites in United States, Canada
- Volunteers
- 63 people
- Sponsor
- Novo Nordisk A/S
Persistent Post Concussive Headache, Mild Traumatic Brain Injury
Pilot TMS in Mild TBI
Persistent post-concussive symptoms (PPCS) involve an array of physical, cognitive, and behavioral symptoms lasting more than a month after mild traumatic brain injury (mTBI).
- Trial name
- NCT06999304
- Testing
- Intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- HealthPartners Institute
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