Clinical trials: Post-traumatic
Traumatic Cataract
Early Vs Late Post Traumatic Cataract Surgery
In a randomized clinical trial, 30 eyes with traumatic cataract after open globe injury with IOL implantation underwent early and 30 eyes underwent late cataract surgery. We excluded patients who were under 12-year-old.
- Trial name
- NCT02900365
- Testing
- early cataract surgery & IOL implantation, late cataract surgery & IOL implantation
- Volunteers
- 60 people
- Sponsor
- Farabi Eye Hospital
Alcohol Use, Posttraumatic Stress Disorder
CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)
The study aims to test the efficacy of a CBT-enhanced text message intervention and a supportive text message intervention to reduce symptom burden in individuals with post-traumatic stress disorder symptoms and co-occurring…
- Trial name
- NCT06648395
- Testing
- CBT Text Messages, Supportive Messages
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- University of Washington
Post-traumatic Stress Disorder, Prehypertension
Sympathetic Overactivity in Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension.
- Trial name
- SO-PTSD (NCT01627301)
- Testing
- Device-Guided Breathing (DGB), Transcutaneous Vagal Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Emory University
PTSD
Cannabidiol and Prolonged Exposure
The trial will include a randomized control trial to evaluate the efficacy of using Cannabidiol (CBD), a non-intoxicating cannabinoid, as an adjunctive to Prolonged Exposure therapy (PE).
- Trial name
- CBD-PE (NCT03518801)
- Testing
- Prolonged Exposure, Cannabidiol
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Family Members, Post Intensive Care Unit Syndrome
Psychological Symptoms and Families of COVID-19 Patients
Families of patients in Intensive Care Units (ICUs) are at increased risk for developing psychological symptoms that can last for months after the patient is discharged.
- Conditions
- Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
- Trial name
- NCT04501445
- Testing
- Written Summary of Rounds
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Rush University Medical Center
Arthritis, Traumatic Arthritis
The Medacta International GMK Sphere Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of GMK Sphere knee prosthesis.
- Conditions
- Arthritis, Traumatic Arthritis, Rheumatoid Arthritis, Poly-arthritis
- Trial name
- NCT02199600
- Testing
- GMK Sphere Knee Replacement
- Where
- 4 sites in Belgium, United Kingdom
- Volunteers
- 500 people
- Sponsor
- Medacta International SA
PTSD
Clinical Trial Intelligent Biometrics for PTSD - Clinical Trial
Posttraumatic stress disorder (PTSD) is a debilitating mental health condition that increases suicide risk and affects up to 20% of military veterans and 8% of the general population.
- Trial name
- NCT04471207
- Testing
- Therapist Guided Prolonged Exposure with BioWare Device, Record Only Prolonged Exposure with BioWare Device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Depression, PostTraumatic Stress Disorder
Study of Effectiveness and Implementation of a Mental Health Intervention With Conflict-affected Communities in Ukraine
This project aims to contribute to the development of a community mental health care system while directly serving the conflict affected population in east Ukraine.
- Trial name
- NCT03058302
- Testing
- CETA (Common Elements Treatment Approach)
- Where
- 3 sites in Ukraine
- Volunteers
- 302 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post-Traumatic Stress Disorder, Sleep Initiation and Maintenance Disorders
Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder
This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors.
- Trial name
- NCT00183430
- Testing
- Prazosin, Psychotherapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
COVID-19, Psychological Distress
Psychological Impact of COVID-19 on Intensive Care Survivors
Psychological distress is commonly experienced by survivors of an intensive care admission, including patients treated during previous pandemics.
- Conditions
- COVID-19, Psychological Distress, Depression, Anxiety
- Trial name
- PIM-COVID (NCT05092529)
- Where
- 50 sites in United Kingdom
- Volunteers
- 1,620 people
- Sponsor
- Royal Liverpool University Hospital
Post Traumatic Stress Disorder, Depression
Acceptance and Commitment Group Therapy for Unaccompanied Minors
Unaccompanied minors (UM) are considered to be a highly vulnerable refugee subgroup. Research has indicated that UM experience traumatic events and consequently develop high levels of psychopathology.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders
- Trial name
- NCT05218031
- Testing
- Acceptance and Commitment Therapy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Stress Disorders, Post-Traumatic, Affect
Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health
Posttraumatic stress disorder (PTSD) has devastating health consequences. Evidence-based PTSD interventions address the substantial burden of PTSD on the health of individuals and societies; however, several individuals receiving…
- Conditions
- Stress Disorders, Post-Traumatic, Affect, Memory
- Trial name
- NCT05523453
- Testing
- Processing of Positive Memories Technique (PPMT), Supportive Counseling (SC)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Texas, Denton, TX
Post-Traumatic Headache
Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction
This study will evaluate the effectiveness of Treximet when taken for post traumatic headache by measuring any change in the number of headache days or any change in a subject's ability to think following treatment with study…
- Trial name
- NCT01053507
- Testing
- sumatriptan/naproxen sodium
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Cady, Roger, M.D.
PTSD, Trauma
Neuroendocrine Risk for PTSD in Women
This study will test for effects of estradiol (E2) on PTSD symptoms and functional magnetic resonance imaging (fMRI) indicators of stress vulnerability, in naturally-cycling women who are not using hormonal birth control.
- Trial name
- NCT03973229
- Testing
- Estradiol patch
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Emory University
Arthrogryposis, Craniofacial Abnormalities
Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Freeman-Sheldon syndrome (FSS) is a rare human neuromusculoskeletal disorder present before birth, involving primarily limb and craniofacial deformities.
- Conditions
- Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
- Trial name
- FSS-QLS (NCT01307475)
- Testing
- PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 6 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Post Traumatic Stress Disorder
Repetitive Transcranial Magnetic Stimulation Plus Reactivation Therapy Efficacy on PTSD Symptom Severity in Resistant PTSD
A French multicenter randomized and double blinded shamed controlled study recruiting patients who present resistant PTSD. The aim of this trial is to assess the efficacy of cerebral modulation by rTMS with simultaneous…
- Trial name
- TraumaStim (NCT06111976)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety, Depression
Quality of Dying in the Intensive Care Unit: Validation of the CAESAR Scale
The purpose of the study is to evaluate the quality of the dying process in french ICUs (assessed by the CAESAR scale) and to compare physicians', nurses' and relatives perceptions and experiences, with a one-year follow-up of…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- CAESAR (NCT01549197)
- Where
- 47 sites in France
- Volunteers
- 475 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
PTSD, Post Traumatic Stress Disorder
Diet Induced Ketosis for Patients With Posttraumatic Stress Disorder (PTSD), a Feasibility Study
Many patients suffering from posttraumatic stress disorder (PTSD) are resistant to established treatment consisting of psychotherapy.
- Trial name
- NCT05415982
- Testing
- Ketogenic Diet
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Jens Rikardt Andersen
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Post-Traumatic Stress Disorder
Enhancing Equitable and Effective (E-3) Post Traumatic Stress Disorder (PTSD) Disability Assessment
This project evaluated the impact of semi-structured, standardized interviews on the initial PTSD C\&P on the examination.
- Trial name
- E-3PTSD (NCT00699660)
- Testing
- CAPS/WHODAS, Nonstructured Interview
- Where
- 11 sites in United States
- Volunteers
- 406 people
- Sponsor
- VA Office of Research and Development
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