Clinical trials: Post-traumatic
Chest Wall Tumors, Post-traumatic Syndrome
"Multicenter Registry for Chest Wall Reconstruction Using Custom Dynamic Prostheses (PRODIPET)"
PRODIPET Study Summary Title: Multicenter Registry for Chest Wall Reconstruction Using Custom 3D-Printed Titanium Prostheses Purpose The PRODIPET study evaluates the safety and effectiveness of personalized, dynamic titanium…
- Conditions
- Chest Wall Tumors, Post-traumatic Syndrome, Malignant Bone Tumor of Chest Wall
- Trial name
- PRODIPET (NCT07018960)
- Testing
- Chest wall reconstruction with 3D printed titan custom prothesis
- Where
- 5 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Post Traumatic Stress Disorder
Psycho-traumatic Consequences of the COVID-19 Health Crisis Among Professionals in Emergency Services
The COVID-19 outbreak has been categorized as a pandemic and declared an international public health emergency by WHO. In this context, an exceptional mobilization and a complete reorganization of the organization of the…
- Trial name
- COVER PRO LT (NCT05033223)
- Testing
- PTSD evaluation of emergency room staff 9 and 12 months after the end of second lockdown in France during COvid-19 pandemic
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Hospices Civils de Lyon
Healthy, Lower Limb Injury
Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics
Carbon fiber custom dynamic orthoses (CDOs) consist of a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that stores and returns energy during gait, and a carbon fiber foot plate that…
- Conditions
- Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
- Trial name
- AFOCUFF (NCT05456295)
- Testing
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Insomnia, Depression - Major Depressive Disorder
Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI)
The goal of this pilot clinical trial is to evaluate the effectiveness and delivery method of a CBTI self-managed digital mobile application in service members. The main questions it aims to answer are: RQ1.
- Conditions
- Insomnia, Depression - Major Depressive Disorder, PTSD
- Trial name
- NCT07335276
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 144 people
- Sponsor
- Madigan Army Medical Center
PTSD, Cardiac Arrest
Acceptance and Mindfulness Based Exposure Therapy for Survivors of Cardiac Arrest
The primary goal of this uncontrolled pilot trial is to examine feasibility, acceptability, safety, and preliminary efficacy of a new behavioral treatment for survivors of sudden cardiac arrest with clinically elevated symptoms…
- Trial name
- AMBET (NCT04596891)
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Post-Traumatic Stress Disorder in Children
Validation of the Turkish Version of PTSD-RI-5
The aim of this study is to investigate the adaptation and validity of the DSM-5 PTSD-RI -5 scale in patients who have been exposed to traumatic events.
- Trial name
- NCT06077474
- Testing
- Testing the the DSM-5 UCLA Posttraumatic Stress Disorder Reaction Index Self-Report Scale for Children and Adolescents (PTSD-RI-5)
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Traumatic Intracranial Hemorrhage
Restart TICrH AP Pilot Trial
A Prospective Randomized Open-Label Blinded Endpoint (PROBE) Pilot Trial of restarting antiplatelet therapy at 1 week versus 3 weeks after traumatic intracranial hemorrhage with a primary composite endpoint of major bleeding and…
- Trial name
- NCT05000060
- Testing
- Timing/1 week, Timing/3 weeks
- Volunteers
- 100 people
- Sponsor
- University of Texas at Austin
Posttraumatic Stress Disorder
Efficacy Mechanism of N-acetylcysteine in Patients With Posttraumatic Stress Disorder
It has been suggested that N-acetylcysteine exerts neuroprotective effects by regulating neurotransmitters and cell signaling pathways.
- Trial name
- NCT01664260
- Testing
- N-acetylcysteine
- Where
- South Korea
- Sponsor
- Ewha Womans University
Acute Respiratory Failure, Shock
Psychological Trauma and Resilience After Critical Illness
Critically ill patients experience a severe physical disease, associated with a psychotrauma, which may lead to post-traumatic stress disorder (17 to 30% of patients after critical illness) and persistent symptoms of anxiety and…
- Trial name
- RESIREA (NCT05193123)
- Where
- 23 sites in France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
MTBI - Mild Traumatic Brain Injury
Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury
The proposed study tests the efficacy (Phase II) of 36 or 54 30-minute training sessions of PATH neurotraining followed by digit memory exercises to improve working memory, processing speed and attention in mTBI patients rapidly…
- Trial name
- NCT03655782
- Testing
- PATH + DigitMemory (DM) neurotraining
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Perception Dynamics Institute
Knee Osteoarthristis, ACL Injuries
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthristis, ACL Injuries, Post-Traumatic
- Trial name
- PTOA Knee (NCT06686680)
- Testing
- extracorporeal shockwave therapy (ESWT)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Spaulding Rehabilitation Hospital
Breast Cancer
Cognition in Breast Cancer Patients: The Impact of Cancer-related Stress
The study will investigate the impact of cancer-related stress and its consequences (acute and posttraumatic stress symptoms, altered cortisol secretion) on cognitive function in breast cancer patients.
- Trial name
- Cognicares (NCT01264562)
- Where
- 6 sites in Germany
- Volunteers
- 254 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders
Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators
Police officers, correctional service officers, and 911-operators are at increased risk for suffering from trauma-related disorders due to their direct and indirect exposure to life-threatening events, such as shootings, violent…
- Conditions
- Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders, Adjustment Disorders, Acute Stress Disorder
- Trial name
- NCT03152175
- Testing
- Propranolol Hydrochloride
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Douglas Mental Health University Institute
Mild Concussion, Post Concussion Syndrome
Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool
The iDETECT (Integrated Display Enhanced Testing for Concussion and mild traumatic brain injury) system is a novel portable, open access platform that enables immediate and rapid assessment of multimodal neurologic function.
- Conditions
- Mild Concussion, Post Concussion Syndrome, Vestibular Neuritis
- Trial name
- NCT02171312
- Testing
- iDETECT Assessment, Routine Balance and Vestibular Testing
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Emory University
Knee Osteoarthritis, Post-traumatic Osteoarthritis
Clinical Evaluation of Vanguard DD RP
This is a single cohort, prospective study of performance and safety of the Vanguard Deep Dish Rotating Platform (DD RP) cementless fixation with the goal to acquire clinical outcomes data and evaluate the performance of the…
- Conditions
- Knee Osteoarthritis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis
- Trial name
- NCT04076202
- Testing
- Cementless Vanguard DD RP
- Where
- Austria
- Volunteers
- 113 people
- Sponsor
- Zimmer Biomet
Traumatic Brain Injury, Posttraumatic Epilepsy
Allopregnanolone for the Treatment of Traumatic Brain Injury
This study will provide initial data on the safety and effectiveness of allopregnanolone in improving neurobehavioral outcome and reducing mortality in adults with moderate and severe traumatic brain injury.
- Trial name
- NCT01673828
- Testing
- Allopregnanolone injection
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Michael A. Rogawski, MD, PhD
Family Relations, Psychological Trauma
Multifamily Healing Spaces for Family Resilience in Rwanda
This cluster-randomized waitlist-control trial evaluated Multifamily Healing Spaces (MFHS), a culturally adapted behavioral family intervention for genocide-affected communities in Rwanda.
- Conditions
- Family Relations, Psychological Trauma, Stress Disorders, Post-Traumatic, Parent-Child Relation
- Trial name
- MFHS-CRT (NCT07621705)
- Testing
- Multifamily Healing Spaces
- Where
- 5 sites in Rwanda
- Volunteers
- 319 people
- Sponsor
- Alexandros Lordos, PhD
Posttraumatic Stress Disorder
Extinction of Fear Memories With Glucocorticoids in Veterans With PTSD
The purpose of this study is to examine the effects of glucocorticoid administration following traumatic memory reactivation on psychiatric symptoms in veterans with combat-related PTSD, in addition to examining the effects of…
- Trial name
- VA CORT (NCT01090180)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- VA Office of Research and Development
Opioid Use Disorder, Posttraumatic Stress Disorder (PTSD)
Integrated Treatment for Opioid Use Disorder and PTSD
This study will test a therapy intervention, HOPE, for individuals with opioid use disorder and posttraumatic stress disorder. Interested individuals will need to be taking medications for opioid use disorder (e.g., suboxone…
- Trial name
- NCT06641115
- Testing
- HOPE Therapy
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
Mild Traumatic Brain Injury, Functional Neurological Disorder
Rehabilitation for Functional Memory Symptoms After Concussion
This study aims to evaluate the feasibility of novel cognitive behavioural therapy (CBT)-based intervention designed to improve functional memory symptoms after concussion.
- Trial name
- NCT05581810
- Testing
- Cognitive Behavioural Therapy (CBT), Cognitive Rehabilitation
- Where
- 10 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
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