Clinical trials: Post-traumatic Stress Symptoms
Posttraumatic Stress Disorder, Depression
The Pitt Center for Emergency Responder Wellness
Emergency responders protect the public despite occupational hazards that threaten their mental health. The Pitt Center for Emergency Responder Wellness will be a clinical innovation hub that: 1) delivers accessible interventions…
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Trial name
- NCT05357586
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tinnitus, Traumatic Brain Injury
Investigating the Neurobiology of Tinnitus
The investigators hypothesize that individual differences exist in resting-state cortical attention, control, sensory, and emotion networks prior to noise exposure and these differences predispose some to the development of…
- Conditions
- Tinnitus, Traumatic Brain Injury, Post Traumatic Stress Disorder
- Trial name
- NCT01294124
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Posttraumatic Stress Disorder
Emotional Working Memory Training for Veterans With PTSD Symptoms
PTSD is characterized by recurrent intrusion of trauma-related memories and images that cause significant distress and impairment to the affected individuals.
- Trial name
- NCT02766296
- Testing
- Active Emotional Working Memory Training, Control Working Memory Training
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Milwaukee VA Medical Center
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Posttraumatic Stress Disorder, Major Depressive Disorder
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel
Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05530642
- Testing
- Emotional Resilience Skills Training (ERST)
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Regina
Post Intensive Care Unit Syndrome, Psychological Trauma
Positive Suggestions Via MP3 Messages
The purpose of this study is to assess the use of an audio recording containing positive suggestion as a means to provide needed psychological support to critically ill patients in a feasible and reliable manner.
- Conditions
- Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression
- Trial name
- NCT04437095
- Testing
- Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Mayo Clinic
Spinal Cord Injuries, Anxiety Disorders
UK Prevalence of Mental Health After SCI
Mental health decline after Spinal Cord Injury (SCI) is commonly reported but minimally investigated in the United Kingdom. The current study aims to explore the prevalence and impact of mental health challenges after SCI to…
- Conditions
- Spinal Cord Injuries, Anxiety Disorders, Depression, PTSD
- Trial name
- NCT06618404
- Testing
- No intervention - cross-sectional cohort analysis
- Where
- United Kingdom
- Volunteers
- 318 people
- Sponsor
- University of Reading
Anxiety, Depression
A Mobile Health Solution for Homework During CBT
The purpose of this study is to preliminarily evaluate a web-based app to improve provider implementation and patient engagement in homework (i.e., between-session practice of skills learned during therapy) during child mental…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04931199
- Testing
- Cognitive Behavioral Therapy (CBT), CBT+App
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of South Florida
Stress Disorder, Post Traumatic, Military Sexual Trauma
Guided Imagery for Military Sexual Trauma-Related Posttraumatic Stress Disorder (PTSD)
Military sexual trauma (MST) is a significant women's mental health issue. There is a crucial need for effective therapies for MST-related posttraumatic stress disorder (PTSD) that are well-tolerated and can be flexibly…
- Trial name
- NCT00635635
- Testing
- Guided Imagery Audio, Music Audio
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Depression, Anxiety
Intervention Effectiveness in Improving Psychosocial and Economic Well-being of Sexual Violence Survivors in DRC
The Democratic Republic of the Congo (DRC) has become synonymous with sexual violence by armed groups within the last 2 decades.
- Conditions
- Depression, Anxiety, PTSD
- Trial name
- NCT01385163
- Testing
- Treatment as usual, Voluntary Savings/Loans Assoc, Cognitive Processing Therapy
- Where
- Democratic Republic of the Congo
- Volunteers
- 706 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
PTSD, Stress, Psychological
The Efficacy of a Physical Activity Counselling Intervention on Mental Health in Firefighters
Objectives: The aim of this project will be to evaluate the efficacy of a lifestyle PA counselling program for physically inactive first responders with at least mild symptoms of either anxiety, depression or stress and their…
- Conditions
- PTSD, Stress, Psychological, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT05061225
- Testing
- Physical activity counselling
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Posttraumatic Stress Disorder, Depression
Loving-Kindness Meditation for PTSD
This randomized controlled trial will assess whether a novel complementary and alternative medicines (CAM) intervention, Loving-kindness Meditation (LKM), is not meaningfully inferior to another group-based PTSD treatment …
- Trial name
- NCT01962714
- Testing
- Loving-Kindness Meditation, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- VA Office of Research and Development
Non Suicidal Self Injury
The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.
Non-suicidal self-injuries (NSSI) is a deliberate harm a person causes directly to their body, resulting in structural or functional damage, without suicidal ideation.
- Trial name
- NCT04242914
- Testing
- Ketamine, Midazolam
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Pain, Traumatic Brain Injury
Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans
This is a research study of an interdisciplinary pain management program for U.S. military veterans who served during the post-9/11 combat eras (e.g., Operations Iraqi Freedom [OIF], Enduring Freedom [OEF], New Dawn [OND])…
- Conditions
- Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression
- Trial name
- NCT02657317
- Testing
- FORT-A, VA Treatment as Usual
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post-Traumatic Stress Disorders
KIDNET vs Meditation/Relaxation - a Dissemination Randomized Controlled Trial for the Treatment of Traumatized Children After War in Sri Lanka
The purpose of this study is to assess the efficacy of KIDNET versus a Meditation/Relaxation protocol in treating traumatized children when applied by locally trained teacher counsellors as well as the effectiveness and adequacy…
- Trial name
- NCT00564317
- Testing
- KIDNET, Meditation/Relaxation
- Where
- Sri Lanka
- Volunteers
- 48 people
- Sponsor
- University of Konstanz
Stress-related Problem, Stress, Emotional
Effects of Parent-Adolescent Joint I-Interventions for Adolescents with Adverse Childhood Experiences
The study aims to examine the effectiveness of internet-based Parent-Adolescent Joint Interventions in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as…
- Trial name
- EASY-PEP-i (NCT06650696)
- Testing
- PCE promotion, Psychoeducation, Emotiaonl skill enhancement
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Mild Traumatic Brain Injury, Distress-based Psychopathology
One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology
Traumatic brain injury (TBI) is the signature wound of Veterans returning from the recent operations in Iraq and Afghanistan (i.e OIF/OEF/OND), with up to 20 percent experiencing persistent post-concussive symptoms.
- Conditions
- Mild Traumatic Brain Injury, Distress-based Psychopathology, Chronic Pain
- Trial name
- NCT02844946
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Three-Arm Quasi-Experimental Study of App-Assisted Acceptance and Commitment Therapy for Post-Traumatic Stress Symptoms
The goal of this clinical trial is to compare the efficacy of three Acceptance and Commitment Therapy (ACT) delivery modalities in treating Post-Traumatic Stress Disorder (PTSD) in adult patients (ages 20-40) with mild to…
- Trial name
- NCT07624708
- Testing
- Acceptance Commitment Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Central Punjab
Major Depression
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
The purpose of this multi-site randomized controlled trial is to evaluate the efficacy and risks of psilocybin for the treatment of depression in U.S.
- Trial name
- PIVOT (NCT07226232)
- Testing
- Psilocybin
- Where
- 5 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Posttraumatic Stress Disorder
CIH Stepped Care for Co-occurring Chronic Pain and PTSD
The goal of this clinical trial is to evaluate the feasibility, acceptability, appropriateness, and retention of patient participants of a CIH Stepped Care approach for co-occurring chronic pain and PTSD vs.
- Trial name
- NCT06219408
- Testing
- CIH Stepped Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington