Clinical trials: PostPartum Depression
Postpartum Depression
Parenting Skills Group for Mothers With Postpartum Depression
The goal of this longitudinal study is to study the effects of a parenting skills group (Circle of Security Parenting, aka COSP) in mothers with postpartum depression.
- Trial name
- NCT05772897
- Testing
- Circle of Security Parenting program
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postpartum Depression, Intimate Partner Violence
Case Management Study for Postpartum Depression and Intimate Partner Violence
The objective of the study was to assess the prevalence, timing, and co-occurrence of positive screens for maternal postpartum depression (PPD) and intimate partner violence (IPV) for women bringing their young infants for…
- Trial name
- NCT00560027
- Testing
- Case Management by Family Support Counselor (not RCT)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postpartum Depression
Escitalopram in the Treatment of Postpartum Depression
This will be an 8-week, open-label trial evaluating the efficacy of escitalopram as monotherapy in the treatment of patients with postpartum depression (PPD).
- Trial name
- NCT01527474
- Testing
- escitalopram
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- BC Women's Hospital & Health Centre
Premature Birth, Obstetric Labor, Premature
Family Nurture Intervention in the NICU
The purpose of this study is to compare neurodevelopment and activity in infants born very preterm (26 to 33 6/7 weeks gestational age (GA)) receiving Standard Care (SC) or Family Nurture Intervention (FNI) in the neonatal…
- Trial name
- NCT02710474
- Testing
- Family Nurture Intervention, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 461 people
- Sponsor
- Columbia University
Postpartum Depression, Depression
Determining Relationships Among Maternity Stress & Sleep
Psychosocial factors, including a previous history of depression, recent stressful life events, sleep disturbances during pregnancy, and depression and/or anxiety during pregnancy have been shown to be associated with an…
- Trial name
- DREAMSS (NCT02133963)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Postpartum Depression
Engage & Connect: A Psychotherapy for Postpartum Depression
This randomized controlled trial compares a novel psychotherapy, Engage \& Connect, with a Symptom Review and Psychoeducation intervention, tailored to reduce postpartum depression.
- Trial name
- NCT05585164
- Testing
- Engage & Connect (E&C), Symptom Review and Psychoeducation (SRP)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Depression, Postpartum, Postpartum Depression
A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression
The purpose of this research study is to test the study drug, NORA520, as a possible treatment for severe postpartum depression (PPD).
- Conditions
- Depression, Postpartum, Postpartum Depression, Post-partum Depression, Postnatal Depression
- Trial name
- NuMom (NCT06285916)
- Testing
- NORA520 Dose 1, NORA520 Dose 2
- Where
- 18 sites in United States
- Volunteers
- 93 people
- Sponsor
- TWi Biotechnology, Inc.
Caesarean Section
Effect of Tramadol in Prevention of Postpartum Depression
The incidence of postpartum depression in Europe and the United States is about 10%, while in China the incidence rate of 15.7-39.8%.
- Trial name
- ETPPD (NCT03309163)
- Testing
- Tramadol, Hydromorphone, Ropivacaine (Epidural analgesia)
- Where
- China
- Volunteers
- 1,230 people
- Sponsor
- Xinqiao Hospital of Chongqing
Postpartum Depression, Postnatal Depression
Phase 2 Clinical Trial of GH001 in Postpartum Depression
This study is a multicenter, open-label, single-arm Phase 2 clinical trial. Approximately 15 female participants with clinically diagnosed postpartum depression (PPD) will be included in this study.
- Trial name
- NCT05804708
- Testing
- GH001
- Where
- 4 sites in Netherlands, United Kingdom
- Volunteers
- 10 people
- Sponsor
- GH Research Ireland Limited
Postpartum Sadness
The Importance of Discharge Education for Mommy Blues
The study will be conducted with participants who will give birth at Farabi Training and Research Hospital in Darıca District, Kocaeli Province.
- Trial name
- NCT06293274
- Testing
- Discharge training
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Pregnancy Related, Eating Disorders
Experiences From Pregnancy and Post-partum Period in Women With a History of Eating Disorders.
Women with the eating disorder bulimia nervosa (BN) have been found to have a higher risk of unplanned pregnancies than healthy women, and experience greater miscarriage, premature birth, birth complications, and postpartum…
- Conditions
- Pregnancy Related, Eating Disorders, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- PREG_PED-t (NCT04815044)
- Testing
- Pregnancy, Post-Partum
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- Ostfold University College
Postpartum Depression
Postpartum Thyroid Measures and Mood
Women with abnormal serum thyroid antibody levels or abnormal TSH and/or T4 values are more likely than their normal counterparts to have higher scores on a common postpartum depression screening test.
- Trial name
- NCT00565032
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Postpartum Depression, Maternal-Fetal Relations
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes
This randomized controlled trial aims to evaluate the effect of listening to the recitation of Surah Al-Inshirah during the early postpartum period after cesarean birth on women's spiritual well-being, depression levels, and…
- Conditions
- Postpartum Depression, Maternal-Fetal Relations, Spirituality
- Trial name
- NCT07354334
- Testing
- Listening to Surah Al-Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Premature Birth, Birth Weight
Fresh RX: NHS 2020
This study is an evaluation of the Fresh Rx: Nourishing Healthy Starts program administered by Operation Food Search, a St. Louis-based nonprofit organization.
- Conditions
- Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization
- Trial name
- NCT04845230
- Testing
- FreshRx Nourishing Healthy Starts
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Postpartum Depression
Expanded Access Protocol of ZULRESSO™ (Brexanolone) Injection for Adult Patients With Postpartum Depression
This is an expanded access program intended to provide access to ZULRESSO™ (brexanolone) injection for the treatment of a limited number of eligible women with postpartum depression during the period prior to commercial…
- Trial name
- NCT03924492
- Testing
- ZULRESSO (brexanolone) injection
- Sponsor
- Supernus Pharmaceuticals, Inc.
Postpartum Depression
Peer Administered CBT for PPD
Postpartum depression (PPD) affects up to 20% of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care.
- Trial name
- PL-CBT (NCT03285139)
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- McMaster University
Childbirth Problems, Perinatal Depression
Daring Birth - Digital Coaching Solution to Improve Childbirth Experience
The aim of the study is to investigate the effectiveness of the Daring Birth digital coaching solution (the Natal Mind app) in enhancing the experience of childbirth.
- Conditions
- Childbirth Problems, Perinatal Depression, Anxiety in Pregnancy, Pregnancy Related
- Trial name
- NCT06585839
- Testing
- Digital coaching solution to improve childbirth experience, Application for the control group
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aalto University
Postpartum Depression, Postpartum Anxiety
Mother-infant Bonding in the Brain: a Mindfulness-based Intervention
The study investigates the effectiveness of the mindfulness-based intervention "Mindful with your Baby" in women with babies between 5-9 months postpartum who experience heightened levels of postpartum depression, anxiety and/or…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Parental Stress
- Trial name
- NCT05830266
- Testing
- "Mindful with your Baby" group-based therapist-guided intervention, "Mindful with your baby" self-guided online intervention
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Tilburg University
Maternal Health, Pregnancy
Understanding the Role of Doulas in Supporting People With PMADs
Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility.
- Conditions
- Maternal Health, Pregnancy, Delivery, Obstetric, Self Efficacy
- Trial name
- NCT05763537
- Testing
- Standard Doula Care Plus PMAD Intervention, Standard Doula Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Montana
Depressive Symptoms, Anxiety Disorders and Symptoms
Pregnancy Without Psychosocial Stress
The project is aimed at children who are exposed to the toxic psychosocial stress present in their mothers during pregnancy or after childbirth.
- Conditions
- Depressive Symptoms, Anxiety Disorders and Symptoms, Depression, Postpartum
- Trial name
- NCT04853693
- Testing
- Mom´s Supporting Mom, Enhanced Treatment As Usual
- Where
- Czechia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic