Clinical trials: Posterior Blepharitis
Meibomian Gland Dysfunction
Evaluation of Dry Eye and Meibomian Gland Dysfunction After Cataract Surgery
Meibomian gland dysfunction (MGD) is a common and important disease has been investigated the pathophysiology, diagnosis, treatment modalities of MGD, however, the changes of MGD after the cataract surgery, the most popular…
- Trial name
- NCT01942642
- Volunteers
- 48 people
- Sponsor
- Yonsei University
Meibomian Gland Dysfunction, Dry Eye Syndromes
Meibomian Gland Dysfunction Management With ZEST Protocol
The purpose of this study is to investigate if cleaning the eyelid margin with the ZEST protocol (Zocular Eyelid System Treatment) in patients intolerant to contact lens wear consequent to Meibomian gland dysfunction (MGD) will…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Ocular Surface Disease
- Trial name
- NCT03968731
- Testing
- Zocular Eyelid System Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Blepharitis
Lipids of the Human Tear Film and Their Effect on Tear Stability
This prospective, randomized, comparative clinical trial evaluates the effect of either oral doxycycline, oral essential fatty acid, or topical azithromycin to modify the secretions of the meibomian gland in subjects with…
- Trial name
- NCT00803452
- Testing
- doxycycline, azithromycin
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Blepharitis
Safety and Efficacy Pilot Study of AzaSite (Azithromycin) in Subjects With Blepharitis
The purpose of this study is to evaluate the safety and efficacy of AzaSite ophthalmic solution, 1% on signs and symptoms of blepharitis.
- Trial name
- NCT00629590
- Testing
- AzaSite®
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Merck Sharp & Dohme LLC
Palpebral Pathologies, Ocular Surface Disease
Management of Eyelid Disorders by Ophthalmologists in Usual Medical Practice
The purpose of this study is to determine the incidence and characteristics of eyelid inflammatory disorders during general ophthalmological consultations and to demonstrate association between palpebral pathologies and ocular…
- Conditions
- Palpebral Pathologies, Ocular Surface Disease, Meibomian Gland Dysfunction
- Trial name
- MEIBUM (NCT01552174)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 185 people
- Sponsor
- Laboratoires Thea
Dry Eye Syndrome
Evaluation of Factors Affecting the Tear-film Lipid Layer Thickness
In this study, the investigators aim to determine the effects of age, sex, history of ocular surgery and contact lens use, and ocular surface and meibomian gland parameters on the lipid layer thickness (LLT) in normal subjects…
- Trial name
- NCT02645045
- Where
- South Korea
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Dry Eye Syndromes
Efficiency and Changes of Cytokines Expression in Tear After Intense Pulsed Light Treating Dry Eye Disease
The aim of the current study is to investigate changes of tear cytokines levels as well as the efficacy and the reduction of demodex infestation after OPT IPL treatment in patients with meibomian gland dysfunction-Associated…
- Trial name
- NCT04165785
- Testing
- OPT IPL, MGX
- Where
- China
- Volunteers
- 64 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Meibomian Gland Dysfunction
Comparison of Lipiflow®-Treatment and a Standard Lid Hygiene Regime
Recently, beneficial effects on Meibomian gland dysfunction (MGD) of a single automated thermal pulsation with the Lipiflow® system have been reported in several case reports.
- Trial name
- NCT01769105
- Testing
- Lipiflow, Lid hygiene regime
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Meibomian Gland Dysfunction
EyeBag Effectiveness in Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD) is a common condition that causes the secretion from meibomian glands in the eyelids to become blocked. Normally, the secretion helps to maintain a healthy tear film.
- Trial name
- MGD (NCT01870180)
- Testing
- EyeBag
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Aston University
Meibomian Gland Dysfunction
Safety, Efficacy and Pharmacokinetics of CBT-008 in Patients With Meibomian Gland Dysfunction
Study Design Structure: Multicenter, randomized, double-masked, vehicle-controlled, parallel group study Duration: 1 month of TID treatment Treatment Groups, Dosing, and Treatment Regimen Study Treatment: CBT-008 topical…
- Trial name
- NCT05261386
- Testing
- CBT-008
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Cloudbreak Therapeutics, LLC
Meibomian Gland Dysfunction
A Study of AGN-195263 for the Treatment of Meibomian Gland Dysfunction
This study will evaluate the safety and efficacy of AGN-195263 compared to vehicle in patients with meibomian gland dysfunction (MGD) in the eyelids.
- Trial name
- NCT01633788
- Testing
- AGN-195263 0.1%, AGN-195263 0.03%, AGN-195263 0.01%
- Where
- 33 sites in United States
- Volunteers
- 232 people
- Sponsor
- Allergan
Dry Eye Disease
Diamond Bur Microblepharoexfoliation, Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye
The goal of this clinical trial is to assess the efficacy and safety of microblepharoeexfoliation (MBE), intense pulse light (IPL) and meibomian gland expression (MGX) combination in patients with meibomian gland dysfunction…
- Trial name
- NCT05857579
- Testing
- Microblepharoexfoliation, Intense pulse light, Meibomian gland expression
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- University of Seville
Meibomian Gland Dysfunction
Safety and Efficacy Study of a Testosterone Eye Drop for the Treatment of Meibomian Gland Dysfunction
The objective of this study is to assess the safety and efficacy of testosterone 0.03% ophthalmic solution compared to vehicle for the treatment of meibomian gland dysfunction.
- Trial name
- NCT00755183
- Testing
- testosterone ophthalmic solution, vehicle of testosterone ophthalmic solution
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- ORA, Inc.
Meibomian Gland Dysfunction
The Efficacy of an Ocular Emulsion in Meibomian Gland Dysfunction
The aim of this study will be to determine the efficacy of this novel, lipid-containing artificial tear on the signs and symptoms of meibomian gland disease.
- Trial name
- NCT01207752
- Testing
- Systane Balance, Optive Lubricant Eye Drops
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Dry Eye Disease (DED), MGD-Meibomian Gland Dysfunction
The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial
This study aims to conduct a randomized controlled clinical trial to compare the efficacy of a new type of massage device - eyelid support plate and glass rod assisted eyelid massage in improving MGD related dry eye symptoms, and…
- Trial name
- NCT07633938
- Testing
- eyelid support plate assisted eyelid massage, glass rod assisted eyelid massage
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dry Eye Syndromes, Meibomian Gland Dysfunction (Disorder)
Blink Reminders and Meibomian Gland Loss in Digital Screen Users
This randomized clinical trial aims to evaluate if a blink reminder program ('BlinkEasy') reduces the progression of Meibomian gland loss in intensive digital screen users over three months , using infrared meibography as the…
- Trial name
- NCT07430137
- Testing
- Digital Blink Reminder Software (BlinkEasy), Visual Hygiene Education (20-20-20 Rule).
- Volunteers
- 28 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Meibomian Gland Dysfunction
Clinical Efficacy of Hormone Replacement Therapy in Treating Perimenopausal Women With MGD
This project aims to evaluate the possible relationship between MGD and HRT in perimenopausal women
- Trial name
- NCT04962386
- Testing
- Hormone replacement therapy
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Meibomian Gland Dysfunction
Effects of Minocycline on Cytokine Levels in Severe Meibomian Gland Dysfunction
One of the important factors in obtaining successful outcomes when treating severe meibomian gland dysfunction (MGD) is to control the existing ocular and eyelid inflammation.
- Trial name
- NCT01600625
- Testing
- oral minocycline hydrochloride treatment
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Yonsei University