Clinical trials: Posterior Blepharitis
Meibomian Gland Dysfunction, Dry Eye Disease
Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD
Clinical Study Evaluating Nordlys™ System with Selective Waveband Technology (SWT)® Intense Pulsed Light (IPL) Applicators for Dry Eye Disease (DED) due to Meibomian Gland Dysfunction (MGD).
- Trial name
- NCT06064071
- Testing
- Nordlys SWT IPL, Meibomian Gland Expression (MGX)
- Where
- 3 sites in United States, Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Meibomian Gland Dysfunction, Blepharitis
Analysis of the Results of Intense Pulsed Light Treatment Previously to Laser Refractive Surgery
Dry eye is often reported as the most common complication after a laser refractive surgery. Any refractive procedure can lead an impact on the corneal surface and the tear film.
- Trial name
- NCT05139511
- Testing
- Study group, Control group
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vissum, Instituto Oftalmológico de Alicante
Meibomian Gland Dysfunction
Stability of Biometry in Meibomian Gland Dysfunction
Accurate biometry is an essential and indispensable tool in preoperative cataract surgery setting to yield optimal postoperative refractive outcome.
- Trial name
- NCT04322656
- Testing
- Lipiflow treatment
- Where
- Austria
- Volunteers
- 31 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Palpebral Pathologies, Ocular Surface Disease
Management of Eyelid Disorders by Ophthalmologists in Usual Medical Practice
The purpose of this study is to determine the incidence and characteristics of eyelid inflammatory disorders during general ophthalmological consultations and to demonstrate association between palpebral pathologies and ocular…
- Conditions
- Palpebral Pathologies, Ocular Surface Disease, Meibomian Gland Dysfunction
- Trial name
- MEIBUM (NCT01552174)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 185 people
- Sponsor
- Laboratoires Thea
Meibomian Gland Dysfunction
A Study of AGN-195263 for the Treatment of Meibomian Gland Dysfunction
This study will evaluate the safety and efficacy of AGN-195263 compared to vehicle in patients with meibomian gland dysfunction (MGD) in the eyelids.
- Trial name
- NCT01633788
- Testing
- AGN-195263 0.1%, AGN-195263 0.03%, AGN-195263 0.01%
- Where
- 33 sites in United States
- Volunteers
- 232 people
- Sponsor
- Allergan
Dry Eye Disease (DED), Meibomian Gland Dysfunction
Treatment Effect of Intense Pulsed Light and Thermal Pulsation Therapy on Meibomian Gland Dysfunction-associated Dry Eye Disease: a Randomized Trial
The goal of this clinical trial is to understand novel treatment methods for meibomian gland dysfunction (MGD)-associated dry eye disease (DED) by comparing two treatment modalities- intense pulsed light (IPL) and thermal…
- Trial name
- NCT06745089
- Testing
- Intense pulsed light, thermal pulsation therapy, Ocular lubricant
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- National Yang Ming Chiao Tung University
Meibomian Gland Dysfunction (Disorder), Dry Eye Syndromes
Effectiveness and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD) is one of the most common causes of dry eye diseases. Over the past decade, several treatment options in MGD have been extensively studied including warm compression, lid hygiene, ocular…
- Trial name
- NCT03518398
- Testing
- Intense Pulsed Light, Standard treatment
- Where
- Thailand
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Blepharitis
Safety and Efficacy Pilot Study of AzaSite (Azithromycin) in Subjects With Blepharitis
The purpose of this study is to evaluate the safety and efficacy of AzaSite ophthalmic solution, 1% on signs and symptoms of blepharitis.
- Trial name
- NCT00629590
- Testing
- AzaSite®
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Merck Sharp & Dohme LLC
Dermatochalasis of Eyelid, Ocular Surface Disease
Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty
This study aims to evaluate the short and long-term effects of skin-only and skin+muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow position.
- Conditions
- Dermatochalasis of Eyelid, Ocular Surface Disease, Meibomian Gland Dysfunction, Dry Eye
- Trial name
- NCT05528016
- Testing
- Upper Eyelid Blepharoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Marmara University
Skin Laxity, Meibomian Gland Dysfunction
Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region
This protocol will evaluate THERMIeyes® for its ability to treat periorbital skin laxity and wrinkles and monitor ocular surface changes and their effect on evaporative dry eye associated with MGD.
- Trial name
- NCT03280069
- Testing
- THERMIeyes® 20 RF System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Meibomian Gland Dysfunction, Dry Eye
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion…
- Trial name
- NCT05306561
- Testing
- Systane iLux thermal pulsation treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Periman Eye Institute
Dry Eye Syndromes, Meibomian Gland Dysfunction
Intense Pulsed Light in Meibomian Gland Dysfunctions
Dry eye disease (DED) is an extremely common disease whose meibomian gland dysfunction is the main etiology. Polychromatic intense pulsed light (IPL) is a promising new therapeutic alternative but few clinical data have been…
- Trial name
- LACRYSTIM (NCT04147962)
- Testing
- intense pulsed light (usual practice)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Meibomian Gland Dysfunction, Dry Eye Syndromes
Meibomian Gland Dysfunction Management With ZEST Protocol
The purpose of this study is to investigate if cleaning the eyelid margin with the ZEST protocol (Zocular Eyelid System Treatment) in patients intolerant to contact lens wear consequent to Meibomian gland dysfunction (MGD) will…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Ocular Surface Disease
- Trial name
- NCT03968731
- Testing
- Zocular Eyelid System Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Chalazia, Chalazion
Intralesional Tetracycline Injection in the Treatment of Chalazia
The investigators propose a study to investigate the role of tetracycline injection into chalazia versus observation alone. The investigators hypothesize tetracycline injection will result in a significant decrease in lesion size…
- Trial name
- TET (NCT01763437)
- Testing
- Tetracycline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Low Level Light Therapy & Skin Pigmentation
The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease.
- Trial name
- NCT07173530
- Testing
- Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Houston
Eyelid Diseases
Evaluation of Satisfaction Regarding Patient's Management of Ocular Surface Diseases
Multicentric study, open label, uncontrolled phase IV in 140 patients with meibomian glands dysfunction . Its objective is to Collect information from patients and ophthalmologists specialized in ocular surface and eyelids to…
- Trial name
- ESPOIR Ext (NCT01189474)
- Testing
- Blephasteam
- Where
- 29 sites in France
- Volunteers
- 104 people
- Sponsor
- Laboratoires Thea
Meibomian Gland Dysfunction, Cataract
Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures
The development of optical coherence tomography (OCT) and its application for in vivo imaging has opened entirely new opportunities in ophthalmology.
- Conditions
- Meibomian Gland Dysfunction, Cataract, Glaucoma, Corneal Transplantation
- Trial name
- NCT03461978
- Testing
- Ultrahigh resolution Spectral Domain OCT
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Vienna
Sjögren's Syndrome, Meibomian Gland Dysfunction
Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?
The investigators hypothesize that the dry eye caused by SS may include the evaporative type, resulting from the MGD. Furthermore, the investigators hypothesize that both pSS and sSS are associated with MGD.To test our…
- Trial name
- NCT03060005
- Testing
- Tears Naturale Forte, liposic
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tung Wah Hospital
Dry Eye
Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients
The purpose of this study is to identify age-related changes in chinese meibomian glands that may be associated with meibomian gland dysfunction (MGD).
- Trial name
- NCT02481167
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Meibomian Gland Dysfunction
Thermal Pulsation Versus Warm Compress Treatment for Meibomian Gland Dysfunction
This study aimed to assess the treatment outcome differences between a single, in-office bilateral treatment with the thermal pulsation system and twice-daily, 10-minute applications of the warm compress mask at home for 8 weeks.
- Trial name
- NCT06326931
- Testing
- thermal pulsation, warm compress
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Jacksoneye