Clinical trials: Posterior Blepharitis
Meibomian Gland Dysfunction
Efficacy and Safety of Thermic Devices in the Treatment of Meibomian Gland Dysfunction
Dry eye syndrome is a common eye disease that affects 1 to 2 out of 10 persons around the planet. One common cause of this disease is the meibomian gland dysfunction.
- Trial name
- NCT03767530
- Testing
- Mibo Thermoflo, Warm compresses and eyelid massage
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Dry Eye Syndromes
Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease
To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in evaporative dry eye disease (DED) patients with meibomian gland disfunction (MGD) and underlying inflammation undergoing…
- Trial name
- NCT04413279
- Testing
- LipiFlow Thermal Pulsation, Dexamethasone Intracanalicular Insert, 0.4mg with LipiFlow Thermal Pulsation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Eye Surgeons of Indiana
Dry Eye, Meibomian Gland Dysfunction
To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern
MGD is a chronic, diffuse abnormality of the meibomian glands, commonly characterized by terminal duct obstruction and/or qualitative/quantitative changes in the glandular secretion.
- Trial name
- NCT05383612
- Testing
- Warm compresses, 3% Diquafosol Sodium Eye Drops
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Meibomian Gland Dysfunction (Disorder), Dry Eye Syndromes
Effectiveness and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD) is one of the most common causes of dry eye diseases. Over the past decade, several treatment options in MGD have been extensively studied including warm compression, lid hygiene, ocular…
- Trial name
- NCT03518398
- Testing
- Intense Pulsed Light, Standard treatment
- Where
- Thailand
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Meibomian Gland Dysfunction
Study to Determine the Effect of Azasite on Corneal Surface Irregularity
The purpose of this study is to evaluate the effect of Azasite on patients with corneal surface irregularity (meibomian gland dysfunction).
- Trial name
- NCT01797107
- Testing
- Azasite
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philadelphia Eye Associates
Meibomian Gland Dysfunction, MGD-Meibomian Gland Dysfunction
Study to Evaluate the Safety and Efficacy of Minocycline Ointment in Subjects With Inflamed Meibomian Gland Dysfunction
To evaluate the efficacy and safety of two strengths of HY02 Ointment versus Vehicle administered twice daily for twelve weeks in subjects with a diagnosis of Inflamed Meibomian Gland Dysfunction.
- Trial name
- NCT03888378
- Testing
- 0.3% Topical Minocycline Ointment, 1% Topical Minocycline Ointment, Topical Vehicle Ointment
- Where
- 20 sites in United States
- Volunteers
- 270 people
- Sponsor
- Hovione Scientia Limited
Dry Eye, Sjogren's Syndrome
Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry Eye
The study aims to test the safety of Repetitive Magnetic Stimulation (RMS) treatment for dry eye disease. Patients are asked to undergo a one-time treatment with Epitech Ocular Magnetic Stimulation Device on one eye in the first…
- Conditions
- Dry Eye, Sjogren's Syndrome, Aqueous Tear Deficiency, Meibomian Gland Dysfunction
- Trial name
- NCT03012698
- Testing
- Ocular Repetitive Magnetic Stimulation (RMS) treatment
- Where
- 3 sites in Israel
- Volunteers
- 29 people
- Sponsor
- Epitech Mag Ltd.
Dry Eye Syndromes
Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD
The purpose of this study is to evaluate if, in patients with meibomian gland dysfunction (MGD), treatment with the Lumenis M22 Intense Pulsed Light (IPL) system causes a reduction in dry eye symptoms post-treatment, compared to…
- Trial name
- NCT02621593
- Testing
- M22-IPL
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Lumenis Be Ltd.
Meibomian Gland Dysfunction
Safety, Efficacy and Pharmacokinetics of CBT-006 in Patients With Meibomian Gland Dysfunction
STUDY DESIGN Structure: Multicenter, randomized, double-masked, vehicle-controlled, parallel group study. Duration: 3 months of TID treatment.
- Trial name
- NCT04884243
- Testing
- CBT-006
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Cloudbreak Therapeutics, LLC
Meibomian Gland Dysfunction, Dry Eye
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion…
- Trial name
- NCT05306561
- Testing
- Systane iLux thermal pulsation treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Periman Eye Institute
Demodex Infestation, Rosacea
Facial Demodicosis and Ocular Demodicosis
To understand the association between facial demodicosis and ocular demodicosis, we plan to enroll patients with facial demodicosis, ocular demodicosis, or both, in order to analyze their clinical presentations, the density of…
- Conditions
- Demodex Infestation, Rosacea, Blepharitis, Meibomian Gland Dysfunction
- Trial name
- NCT04377841
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Dry Eye Disease, Meibomian Gland Dysfunction
Safety of Tinted Soft Scleral Eye Shields When IPL is Applied on Eyelids
The purpose of this study is to verify the safety of tinted soft scleral eye shields when IPL is applied directly on eyelids.
- Trial name
- NCT05168670
- Testing
- Protection of eyes with tinted soft scleral eye shields
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lumenis Be Ltd.
Dry Eye, Evaporative Dry Eye Disease
Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction
Dry eye disease (DED) is a common chronic condition characterized by ocular surface discomfort and tear film instability. Evaporative DED associated with meibomian gland dysfunction (MGD) is a frequent phenotype and is often…
- Conditions
- Dry Eye, Evaporative Dry Eye Disease, Meibomian Gland Dysfunction (Disorder)
- Trial name
- NCT07453212
- Testing
- Dietary Supplement: Microbiome-targeted oral supplement
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Varol TUNALI
Dry Eye Syndromes
Treatment Regimens in Meibomian Gland Dysfunction
This study seeks to explore the relevance of inflammation in dry eye patients with MGD and compare the efficacy of LipiFlow treatment followed by lid hygiene and lubricant treatment with Systane Ultra or LipiFlow treatment…
- Trial name
- NCT05594745
- Testing
- Lifitegrast Ophthalmic, Systane Free, Lipiflow
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tauber Eye Center
Dermatochalasis of Eyelid, Ocular Surface Disease
Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty
This study aims to evaluate the short and long-term effects of skin-only and skin+muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow position.
- Conditions
- Dermatochalasis of Eyelid, Ocular Surface Disease, Meibomian Gland Dysfunction, Dry Eye
- Trial name
- NCT05528016
- Testing
- Upper Eyelid Blepharoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Marmara University
Dry Eye, Dry Eye Syndromes
Lacrima VR for Dry Eye Disease and Meibomian Gland Dysfunction
This is a prospective, multi-center, randomized, sham-controlled clinical investigation designed to evaluate the safety and effectiveness of the Lacrima VR system in adult subjects with Dry Eye Disease (DED) and Meibomian Gland…
- Trial name
- CLN-0154 (NCT07415330)
- Testing
- Lacrima VR System
- Volunteers
- 20 people
- Sponsor
- Demaod Ltd
Meibomian Gland Dysfunction, Dry Eye
Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye
The study objective is to evaluate the long-term treatment effectiveness for adult patients with meibomian gland dysfunction (MGD) and evaporative dry eye by: 1) comparing the LipiFlow® System to a standardized daily warm…
- Trial name
- NCT01521507
- Testing
- LipiFlow System, Warm Compress Therapy + Lid Scrub
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- TearScience, Inc.
Dry Eye Syndromes
Estrogen and the Outer Eye in Women During Fertility Treatment
The purpose of this study is to determine the relation between estrogen and progesterone levels, and between dryness of the eyes, in women during their fertile years.
- Trial name
- NCT02072122
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Meibomian Gland Dysfunction
Lipiflow Versus Warm Compresses in Parkinson's Disease
The LipiFlow System (TearScience, Morrisville, NC) is an in-office FDA approved treatment for meibomian gland dysfunction. It relieves meibomian gland obstruction through the use of heat and pulsatile pressure.
- Trial name
- NCT02894658
- Testing
- LipiFlow system, Warm compresses
- Sponsor
- Wake Forest University Health Sciences