Clinical trials: Posterior Spinal Fusion
Spinal Stenosis, Pain, Postoperative
Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery
Major purpose of this research is to evaluate the effect and usefulness of Buprenorphine transdermal system (MTDS) among the patients with lumbar spinal disease who was performed the single-level posterior lumbar fusion.
- Trial name
- NCT02416804
- Testing
- Buprenorphine, Tramadol
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Hospital
Spondylolisthesis
Posterior Lateral Fusion (PLF) With Dynesys
The primary purpose of this study is to track and document the clinical outcomes of patients with radicular pathology following posterior lateral fusion with the Dynesys Spinal System.
- Trial name
- NCT00791180
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Zimmer Biomet
Low Back Pain
Clinical, Morphological and Functional Success Predictors Following Lumbar Spinal Surgery in Patients With Chronic Low Back Pain and Degenerative Disorders.
The long term goal of this project is dual fold. First, the investigators wish to derive, validate and then test the impact of a clinical prediction rule to determine which patients who suffer from CLBP with degenerative changes…
- Trial name
- NCT02444702
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Scoliosis, Kyphosis
Comparison of Actifuse ABX and Local Bone in Spinal Surgery
This study is being done to compare people who had a standard of care spinal fusion using part of their local bone graft (a small amount of bone from the region of the spine where the fusion is occurring) to correct an adult…
- Conditions
- Scoliosis, Kyphosis, Lordosis
- Trial name
- NCT01852747
- Testing
- Multilevel Spinal fusion with Actifuse ABX®
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Ohio State University
Thoracic Spine Fracture, Lumbar; Spine, Fracture
Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit
The goal of this observational study is to compare the long-term clinical outcomes of two treatment methods (conservative therapy and surgical treatment) in patients with fractures of the thoracic and lumbar spine without…
- Conditions
- Thoracic Spine Fracture, Lumbar; Spine, Fracture, Thoracolumbar Burst Fracture, Fracture of Spine, Level Unspecified
- Trial name
- NCT06059820
- Testing
- rehabilitation treatment, Spine fusion
- Where
- 2 sites in Russia
- Volunteers
- 40 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Intervertebral Disc Degeneration
Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery
The purpose of this study is to collect on-label safety and efficacy data where InQu Bone Graft Extender is applied to transforaminal lumbar interbody fusion (TLIF) and posterior lumbar interbody fusion (PLIF).
- Trial name
- Intebody (NCT02400762)
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- ISTO Technologies, Inc.
Multi-Level Degenerative Lumbosacral Spinal Conditions
A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions
The purpose of this study is to obtain safety and effectiveness data on the investigational device for multi-level PLF procedures and determine the most appropriate rhBMP-2 dose for use in this indication.
- Trial name
- NCT03118505
- Testing
- Infuse Bone Graft, Medtronic DBM
- Where
- 17 sites in United States
- Volunteers
- 100 people
- Sponsor
- Medtronic Spinal and Biologics
Isthmic Spondylolisthesis, Surgical Procedure, Unspecified
Isthmic Spondylolisthesis Treated With Combined Approach: Clinical and Radiological Outcomes
This study aims to evaluate clinical and radiological outcomes of isthmic spondylolisthesis surgically treated with combined approach.
- Trial name
- SPLAC (NCT03585439)
- Testing
- Observational study evaluating the results of an intervention for isthmic spondylolisthesis: surgical procedure with double approach: Anterior lumbar Interbody Fusion then postero-lateral fusion
- Where
- France
- Volunteers
- 87 people
- Sponsor
- CMC Ambroise Paré
Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion
Laminectomy with internal fixation and osseofusion is a common surgery for treating degenerative spinal diseases. It removes excessive bone spurs and removes the lamina for decompression to relieve nerve compression, and then…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Spinal Stenosis, Scoliosis
- Trial name
- NCT06532968
- Testing
- ORION spinal lamina cover
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Orion Biotech Inc.
Posterior Cervical Spinal Surgery, Myelopathy Cervical
Cervical Orthosis Versus no Orthosis Following Multi-level Posterior Cervical Fusion
Use of cervical orthosis after instrumented posterior cervical spinal surgery is still widely practiced even though modern fusion techniques likely do not require additional stabilization from an external orthosis.
- Conditions
- Posterior Cervical Spinal Surgery, Myelopathy Cervical, Radiculopathy, Cervical, Spinal Stenosis Cervical
- Trial name
- NCT04308122
- Testing
- Cervical Orthosis (CO), No Orthosis
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Dr. Christopher Bailey
Pain
Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis
Patient-controlled Intermittent epidural bolus versus epidural infusion for posterior spinal fusion after adolescent idiopathic scoliosis. Scoliosis surgery is commonly performed in adolescent due to idiopathic scoliosis.
- Trial name
- NCT02669004
- Testing
- Intermittent bolus epidural morphine, continuous epidural morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Inonu University
Low Back Pain, Lumbar Spinal Fusion
Back to Life - Early Rehabilitation Therapy for Patients Undergoing Lumbar Spinal Fusion
Aim This study aims to assess the effectiveness of an early intervention comprising individually tailored physiotherapy, including dialogue, education, and graded activity, following lumbar spinal fusion surgery.
- Trial name
- Back to Life (NCT07378735)
- Testing
- SOGA - Socratic dialogue and Graded Activity, SOGA - SOcratic dialougue and Graded-Activity, SOGA - SOcratic dialogue and Graded-Activity
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Degenerative Disc Disease
Multicenter Study of the Avenue L Interbody Spinal Fusion System Using VerteBRIDGE Plating and Posterior Fixation
The purpose of this prospective clinical study is to examine the short-term safety and efficacy of the Avenue®- L interbody Spinal Fusion System with VerteBRIDGE® plating to treat one and two level degenerative disc disease…
- Trial name
- NCT02068768
- Testing
- Avenue® L Interbody Fusion System (LDR Spine)
- Where
- 4 sites in United States
- Volunteers
- 13 people
- Sponsor
- LDR Spine USA
Surgical Site Infection
Suprafascial Vancomycin Powder for Prevention of Surgical Site Infections After Instrumented Posterior Spinal Fusion
Surgical site infections (SSI) after spine surgery may occur in up to 12% of cases and can lead to increased morbidity, and healthcare costs In this randomized controlled trial the investigators aim to prospectively investigate…
- Trial name
- VANCO (NCT04017468)
- Testing
- Vancomycin
- Where
- 7 sites in Switzerland
- Volunteers
- 450 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Failed Back Surgery Syndrome, Degeneration Lumbar Spine
Restoring Segmental Lumbar Lordosis After Failed Previous Fusion at the Same Level
The restoration of lumbar lordosis is mandatory during lumbar fusion surgery for degenerative disc disease, since not restoring lumbar lordosis adequately may adversely affect surgical outcomes and the patient's quality of life…
- Conditions
- Failed Back Surgery Syndrome, Degeneration Lumbar Spine, Degenerative Spondylolisthesis, Sagittal Imbalance
- Trial name
- NCT07050290
- Testing
- Restoring segmental lordosis at the lumbar spine
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF)
Effect of Addition of Dexmedetomidine During Ultrasound Guided Bilateral Single Shot Erector Spinae Plane Block in Patients Undergoing Posterior Lumbar Interbody Fusion Under General Anesthesia
Posterior lumbar interbody fusion (PLIF) is the management of choice in double level lumbar (L) spondylolisthesis (L3-L5) after ineffective conservative treatment.
- Conditions
- Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF), Lumbar Fixation Surgery
- Trial name
- NCT03746418
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Spinal Fusion, Postoperative Recovery
Swimming-Based Rehabilitation for Recovery After Thoracolumbar Spinal Fusion
This study evaluates the effectiveness and safety of a structured swimming-based rehabilitation program in patients undergoing thoracolumbar spinal fusion.
- Conditions
- Spinal Fusion, Postoperative Recovery, Low Back Pain, Rehabilitation
- Trial name
- AQUA-SPINE (NCT07596238)
- Testing
- Swimming-Based Rehabilitation, Standard Rehabilitation
- Where
- Vietnam
- Volunteers
- 124 people
- Sponsor
- Tra Vinh General Hospital
Adult Spinal Deformity, Scoliosis
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
- Conditions
- Adult Spinal Deformity, Scoliosis, Kyphosis
- Trial name
- NCT04888104
- Testing
- Index or revision spine surgery for complex adult spinal deformity
- Where
- 9 sites in United States
- Volunteers
- 225 people
- Sponsor
- International Spine Study Group Foundation
Low Back Pain
The Effect of Graded Activity and Pain Education (GAPE) for Patients Early After Lumbar Spinal Fusion
Background An increasing number of patients with chronic low back pain (CLBP) undergo lumbar spinal fusion (LSF). Unfortunately, a substantial part of the patients still has persistent pain, functional disability and poor quality…
- Trial name
- NCT04103970
- Testing
- Graded Activity and Pain Education (GAPE)
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Adolescent Idiopathic Scoliosis (AIS)
Effectiveness of Virtual Reality- Based Rehabilitation Program in Individuals With Adolescent Idiopathic Scoliosis After Posterior Fusion Surgery
The aim of this clinical study is to investigate the effect of virtual reality based rehabilitation program on kinesiophobia, respiratory muscle strength, spinal mobility, physical activity, spinopelvic parameters and quality of…
- Trial name
- NCT06753383
- Testing
- To the Virtual Reality Based Exercise, Routine physiotherapy and rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Elif Yagmur Ozger