Clinical trials: Posterior Spine Surgery
Spine Disease, Regional Anaesthesia
Erector Spine Block for Back Surgery
In spine surgery postoperative pain can often be severe and difficult to treat.With the use of ultrasound, the performance of plane blocks and other techniques like root blocks, facet infiltration have become possible without the…
- Trial name
- NCT03214536
- Testing
- erector spinae block, Ropivacaine, Spine surgery
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Antwerp
Lumbar Spine Degeneration, Cervical Spine Degeneration
Randomized Controlled Trial Comparing Irrisept Versus Normal Saline for Wound Irrigation After Posterior Spine Surgery
To compare post-operative wound complications in patients randomized to normal saline versus Irrisept solution and any other adverse reactions from the solution.
- Trial name
- Irrisept (NCT05408923)
- Testing
- saline 0.9%, (0.05% chlorhexidine gluconate (CHG) in sterile water)
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Obesity, Lumbar Spine Surgery
WoundVac in Obese Patients Undergoing Lumbar Surgery
This is an open label, randomized clinical trial of Closed-Incision Negative-Pressure Therapy to decrease post-operative wound complications in patients with BMI ≥35kg/m2 after posterior lumbar spine surgery.
- Trial name
- NCT03688438
- Testing
- Closed-Incision Negative-Pressure Therapy
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Norton Leatherman Spine Center
Vertebral Subluxation, Spine Disease
Erector Spinae Block vs Morphine in Vertebral Fixation
The study aims to shed light about the potential role of Erector Spinae Block in the management of postoperative pain following vertebral fixation surgery via posterior approach.
- Conditions
- Vertebral Subluxation, Spine Disease, Spondylolisthesis
- Trial name
- ATLANTE (NCT04729049)
- Testing
- Erector Spinae plane Block, Patient controlled analgesia with intravenous morphine
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- AUSL Romagna Rimini
Decompression, Surgical
A Study on the Use of Educational Programs Prior to Lumbar Spinal Surgery
This study evaluated the hypothesis that the implementation of an educational program that informs spine patients about their condition, treatment options, prioritization on the wait list, and post-operative care would improve…
- Trial name
- NCT00719485
- Testing
- Educational program
- Volunteers
- 70 people
- Sponsor
- Sunnybrook Health Sciences Centre
Low Back Pain, Opiate Addiction
Study of Opioid Use After Lumbar and Cervical Spine Surgery
The purpose of this project is to assess the impact of an educational video on the use of prescription opioid medication during a 6-month period following spine surgery.
- Conditions
- Low Back Pain, Opiate Addiction, Neck Pain
- Trial name
- SOULCS (NCT02674711)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Spinal Fusion, Spinal Deformity
Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation
Background: Throughout the history of spinal deformity there have been continuous advances in the surgical treatment. Although many techniques have been successfully developed despite the anatomy complex, screw placement still…
- Conditions
- Spinal Fusion, Spinal Deformity, Spine Injury
- Trial name
- NoHARM (NCT06020417)
- Testing
- O-ARM (Medtronic, Inc, Louisville, CO), Conventional corrective surgery for arthrodesis
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Federal University of Piaui
Disc Degenerative Disease, Spine Fusion for Degenerative Spine Disease
Comparison of Posterior Cellular Bonegraft Options for Single Level Lumbar Spinal Fusion
This study involves the assessment of alternatives to iliac bone graft during spinal fusion surgery. Four types of bone graft alternatives are being compared to iliac bone graft during the posterior portion of an…
- Trial name
- NCT07187362
- Testing
- Use iliac bone graft, use bone morphogenetic protein, use bone derived allograft MSCs
- Volunteers
- 119 people
- Sponsor
- Midwest Spine & Brain Institute
Low Back Pain, Lumbosacral Radiculopathy
A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief
The purpose of this study is to collect information about how patients feel when doctors manage their pain after lumbar spine surgery using a combination of EXPAREL® and bupivacaine injected into the lumbar spine at the end of…
- Conditions
- Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation
- Trial name
- NCT03514277
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Back Pain, Fusion of Spine, Lumbar Region
The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
The postoperative pain of lumbar fusion surgery is very severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Conditions
- Back Pain, Fusion of Spine, Lumbar Region, Spinal Stenosis
- Trial name
- NCT03047044
- Testing
- Optimizing basal infusion (B.I), Conventional PCA mode
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cervical Spine Surgery, Pain Management
The Effect of High-thoracic Erector Spinae Plane Block on Postoperative Pain and Diaphragmatic Function in Posterior Cervical Spine Surgery
Posterior cervical spine surgery, often performed on older individuals with significant comorbidities, is one of the most painful surgical operations.
- Trial name
- NCT06721832
- Testing
- Erector spina plane block (ESP), Bupivacain (preoperative)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Spine Surgery, Low Back Pain
Transverse Abdominis Plane Block for Anterior Approach Spine Surgery
Therapeutic, prospective, randomized, double blind, placebo-controlled, in intention to treat, monocentric study to evaluate the analgesic efficacy of a bilateral TAP block after spine surgery with 24 hours morphine consumption
- Conditions
- Spine Surgery, Low Back Pain, Spondylolisthesis
- Trial name
- TAP ALIF (NCT02884440)
- Testing
- TAP block ropivacaine, General anesthesia
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Rennes University Hospital
Low Back Pain
Influence of Supervised Stabilization Exercises on Postural Control in Patients After Spine Surgery.
The aim of the study is to determine the impact of early rehabilitation in patients after lumbar spine surgery using microdiscectomy on balance, postural stability and foot pressure distribution.
- Trial name
- NCT05190003
- Testing
- Experimental Study
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Chronic Low-back Pain, Postsurgical Pain
Postoperative Telehealth Mindfulness Intervention After Spine Surgery
Lumbar spine pain is the leading cause of years lived with a disability and affects over 50 million individuals in the United States.
- Conditions
- Chronic Low-back Pain, Postsurgical Pain, Opioid Use, Lumbar Spine Surgery
- Trial name
- NCT04648683
- Testing
- Individual telehealth mindfulness, Group telehealth mindfulness
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of RECK in Posterior Spinal Fusion
"RECK" is a combination of local anesthesia medications, used for the purpose of pain control. RECK is an acronym which stands for Ropivacaine, Epinephrine, Clonidine, and Ketorolac.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Trial name
- NCT06447194
- Testing
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Smoking Cessation
Stop Smoking in Spine Surgery
Patients that are subjected to a medium complex surgical intervention in neck (posterior) or lumbar spine (posterior) with instrumentation are motivated to stop smoking.
- Trial name
- NCT06361459
- Testing
- Stop smoking
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Leiden University Medical Center
Scoliosis; Spinal Fusion; Blood Transfusion; Operative Blood Loss
Blood Transfusion Risk Factors and Cell Saver Impact in Pediatric Scoliosis Surgery
Spine surgery for scoliosis correction in pediatric patients is a major procedure associated with a high risk of perioperative blood loss.
- Trial name
- NCT07661589
- Testing
- posterior Instrumented Spinal Fusion, Intraoperative Cell Saver Autologous Reinfusion
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Mehdi Trifa
Spine Fusion, Postoperative Pain
Effect of Introperative Ketamine and Lidocaine Infusion on Postoperative Opioid Consumption in Posterior Spinal Fusion Surgery
Objective: The primary aim of this study was to investigate the effect of ketamine and lidocaine on postoperative opioid consumption in posterior spinal fusion surgery.
- Trial name
- NCT04711668
- Testing
- Ketamine, Lidocain, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ataturk University
Spinal Tumor, Traumatic Injury of Spine
Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery
The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7…
- Conditions
- Spinal Tumor, Traumatic Injury of Spine, Degenerative Spine Disease
- Trial name
- NCT04578691
- Testing
- "Anatase" Spine Surgery Navigation System, Medtronic Stealthstation S7 Treatment Guidance System
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Back Pain, Cognitive Behavioral Therapy
Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery
This study investigates a Cognitive Behavioral Therapy (CBT) intervention for women who are undergoing elective surgery. The objective is to provide a toolkit of stress management techniques to decrease pain and opioid use…
- Conditions
- Back Pain, Cognitive Behavioral Therapy, Surgery
- Trial name
- NCT06335485
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Brigham and Women's Hospital