Clinical trials: Posterior Vitreous Detachment
Neovascular Age-related Macular Degeneration
Intravitreal Ranibizumab in Exudative Age-related Macular Degeneration With Posterior Vitreomacular Adhesion
The main objective is to determine the efficacy of intravitreal administration of Ranibizumab combined with intravitreous injection of expansile gas and induction of posterior vitreous detachment on best-corrected visual acuity…
- Trial name
- NCT01291121
- Testing
- Intravitreal expansile gas and ranibizumab injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Retinal Vein Occlusion, Posterior Vitreous Detachment
Posterior Vitreous Detachment (PVD) Assessment During Dual Retinal Vein Occlusion (RVO) Lucentis Evaluations
This is a study of subjects with retinal vein occlusion (RVO) specifically looking at the difference in outcomes between patients with posterior vitreous detachment (PVD) and those without PVD.
- Trial name
- PADDLE (NCT00831350)
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Barnes Retina Institute
Vitreoretinal Traction Syndrome
Study to Evaluate Plasmin for the Creation of a Posterior Vitreous Detachment
Plasmin is expected to create a posterior vitreous detachment. The pharmacological creation of a posterior vitreous detachment may be beneficial in a variety of conditions.
- Trial name
- NCT00348439
- Testing
- Plasmin, Vehicle
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Bausch & Lomb Incorporated
Vitreous Detachment
Comparison of Propofol Target Controlled Infusion (TCI) and Sevoflurane
This study was an experimental, single-blinded, randomized controlled trial that aimed to compare recovery time between TCI propofol and sevoflurane.
- Trial name
- NCT04865991
- Testing
- TCI Propofol, Sevoflurane
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Macular Hole, RPE Detachment
Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies
The purpose of this study is to compare the newly released Spectral OCT/SLO (OTI, Toronto, Canada) with the Zeiss Stratus OCT (Carl-Zeiss Meditec, Dublin, CA) with regards to the quality of the images obtained as well as the ease…
- Conditions
- Macular Hole, RPE Detachment, Epiretinal Membrane, Posterior Vitreous Detachment
- Trial name
- NCT00408720
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The New York Eye & Ear Infirmary
Vitrectomy
A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)
A multicenter study to compare multiple doses of intravitreal microplasmin in patients undergoing surgical vitrectomy.
- Trial name
- NCT00412958
- Testing
- Ocriplasmin 25µg, Ocriplasmin 75µg, Ocriplasmin 125µg
- Where
- 20 sites in United States
- Volunteers
- 125 people
- Sponsor
- ThromboGenics
Posterior Vitreous Detachment
The Incidence of Complete Posterior Vitreous Degeneration After Phacoemulsification
Intraocular surgery could induce vitreous degeneration and then abnormal posterior vitreous detachment (PVD) could occur including vitreoschisis and partial-thickness PVD.
- Trial name
- NCT04727398
- Testing
- Wide-field optical coherence tomography (Optovue®)
- Where
- Thailand
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Posterior Vitreous Detachment, Diabetic Retinopathy
Annular Array Ultrasound in Ophthalmology
The objective of this research is to improve the care of ocular disease and disorders, in particular the changes in the eye associated with diabetes, by providing clinicians with dramatically improved ultrasonic images of the…
- Trial name
- NCT01415037
- Testing
- annular array ultrasound exam
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Columbia University
Vitreous Detachment, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Vitreous Modifications After Cataract Surgery
This study aims to evaluate changes in vitreous structure and the vitreoretinal interface following cataract surgery using spectral-domain optical coherence tomography (OCT).
- Trial name
- VitCat (NCT07816887)
- Testing
- cataract surgery
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University of Trieste
Vitreous Detachment, Diabetic Retinopathy
Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment
The purpose of this study is to assess the efficacy of intravitreous injections of Vitrase to induce posterior vitreous detachment(PVD) in subjects with moderate to severe non-proliferative diabetic retinopathy.
- Trial name
- NCT00198471
- Testing
- Vitrase
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Bausch & Lomb Incorporated
Endophthalmitis, Cataract
Early Vitrectomy for Endophthalmitis After Cataract Surgery
Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness.
- Conditions
- Endophthalmitis, Cataract, Vitreous Detachment, Retinal Detachment
- Trial name
- NCT05249413
- Testing
- Early 23-gauge pars-plana vitrectomy
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Benha University
Diabetic Macular Edema
Evaluation of the Role of Intravitreal Tissue Plasminogen Activator in Treatment of Refractory Diabetic Macular Edema
Purpose: to evaluate the effect of intravitreal injection of tissue plasminogen activator(tPA) in treatment of refractory diabetic macular edema(DME).
- Trial name
- NCT01141881
- Testing
- Tissue Plasminogen Activator,bevacizumab ,follow up
- Where
- Iran
- Sponsor
- Mashhad University of Medical Sciences
Epiretinal Membrane, Macular Hole
UNITY VCS Vitreoretinal Surgery
This purpose of this study is to compare the safety and effectiveness of two eye surgery systems-UNITY VCS and CONSTELLATION-in treating adults with vitreoretinal diseases or disorders.
- Conditions
- Epiretinal Membrane, Macular Hole, Visually Significant Vitreous Floater, Vitreomacular Traction
- Trial name
- NCT07054281
- Testing
- UNITY Vitreoretinal Cataract System (VCS), CONSTELLATION Vision System, Vitreoretinal ophthalmic surgery
- Where
- 8 sites in United States
- Sponsor
- Alcon Research
Vitreomacular Adhesion
Prevalence of Vitreomacular Adhesion in Patients 40 Years and Older
The purpose of this study is to evaluate the prevalence of vitreomacular adhesion (VMA) in patients 40 years and older using Spectral Domain Optical Coherence Tomography.
- Trial name
- VAST (NCT02160340)
- Where
- 18 sites in United States
- Volunteers
- 1,584 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Optic Disc Pit Maculopathy
Vitrectomy for Optic Disc Pit Maculopathy
The purpose of this study is to evaluate the efficacy of vitrectomy, without gas tamponade or laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with optic disc pits and to…
- Trial name
- NCT01340703
- Testing
- vitrectomy without laser or gas tamponade
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Kyorin University