Clinical trials: Postmenopausal Diabetes
Metabolic Syndrome
Effect of Genistein in Women With Metabolic Syndrome
The purpose of this study is to determine whether the phytoestrogen genistein is effective in improving bone condition in pre-menopausal and post-menopausal women suffering for osteopenia.
- Trial name
- NCT00541710
- Testing
- genistein
- Where
- 3 sites in Italy
- Volunteers
- 120 people
- Sponsor
- University of Messina
Type 2 Diabetes Mellitus
An Investigation Into Bone Micro-architecture in Women With Type 2 Diabetes
The number of people with type 2 diabetes is growing. This puts a lot of pressure on the health care systems. Type 2 diabetes is often associated with health problems, like poor eyesight, muscle coordination, muscle strength, and…
- Trial name
- NCT00982371
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Diabetes, Diabetes Mellitus, Type 2
A Trial Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Ethinylestradiol and Levonorgestrel in an Oral Contraceptive Combination Drug in Healthy Postmenopausal Females
This trial is conducted in Europe. The aim of the trial is to investigate the influence of oral semaglutide on pharmacokinetics (the exposure of the trial drug in the body) of ethinylestradiol and levonorgestrel in an oral…
- Trial name
- NCT02845219
- Testing
- semaglutide, SNAC, Microgynon®
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Osteoporosis, Postmenopausal, Diabetes Mellitus, Type 2
Effect of GLP-1 Receptor Agonists on Trabecular Bone Score
This study will help determine the effect of Glucagon Like Peptide-1 (GLP-1)receptor agonists on bone strength in postmenopausal women with type 2 diabetes mellitus (T2DM)
- Trial name
- NCT04964388
- Testing
- GLP-1 receptor agonist
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Mississippi Medical Center
Depression, Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women
Desvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). The sustained-release (SR) formulation, DVS SR, is being studied in the development program for the treatment of…
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00369343
- Testing
- Desvenlafaxine administered as a succinate salt in a sustained-release form (DVS SR)
- Where
- 37 sites in United States
- Volunteers
- 381 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Diabetes Mellitus, Diabetes Mellitus, Type 2
Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 Diabetes
The study tests whether pioglitazone (PIO)as compared to metformin (MET)affects bone health including bone mineral density, bone turnover markers, and osteocyte biomarker in patients with type 2 diabetes (T2DM).
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, Glucose Metabolism Disorders
- Trial name
- Pioglitazone (NCT01935804)
- Testing
- Pioglitazone, Metformin
- Where
- Saudi Arabia
- Volunteers
- 440 people
- Sponsor
- King Abdulaziz University
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Postmenopausal, Prediabetes
Glucose-Guided Eating Pilot
This is a single center, parallel-arm randomized controlled pilot study that aims to examine the feasibility and acceptability of the glucose-guided eating (GGE) mobile app and intervention in two populations at risk of chronic…
- Conditions
- Postmenopausal, Prediabetes, Adolescent and Young Adult (AYA) Cancer Survivors
- Trial name
- GET CHARGED (NCT05998460)
- Testing
- Glucose-Guided Eating with CGM, CGM only
- Volunteers
- 100 people
- Sponsor
- Georgetown University
Metabolic Syndrome
Effects of Genistein in Postmenopausal Women With Metabolic Syndrome
The 15-25% of the population of developed countries suffers for metabolic syndrome. It is associated with a 2-4 fold increase in cardiovascular morbility and mortality and with a 5- 9 fold increase in developing type II diabetes.
- Trial name
- NCT01664650
- Testing
- Genistein
- Where
- 3 sites in Italy
- Volunteers
- 120 people
- Sponsor
- University of Messina
Diabete Type 2
Vascular and Metabolic Changes in Postmenopausal Diabetics
The presence of type 2 diabetes mellitus (T2DM) also increases the relative risk of developing cardiovascular disease in women compared to men.
- Trial name
- NCT03273738
- Testing
- folate level measurement, B12
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2
Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health
The purpose of this study is to determine the effects of rosiglitazone on the bone in postmenopausal women with type 2 diabetes mellitus
- Trial name
- NCT00679939
- Testing
- Rosiglitazone, Metformin
- Where
- 42 sites in United States, Argentina and 6 more
- Volunteers
- 226 people
- Sponsor
- GlaxoSmithKline
Metabolic Syndrome, Postmenopausal Symptoms
Circadian Rhythms in Postmenopausal Women
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms…
- Trial name
- NCT04893226
- Testing
- Time-Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Osteoporosis, Postmenopausal, Type 2 Diabetes
Use of Ibandronate in Diabetic Patients
The purpose of this study is to examine whether monthly oral administration of ibandronate to postmenopausal osteoporosis patients with type 2 diabetes differs in safety and efficacy compared to patients without diabetes.
- Trial name
- NCT05266261
- Testing
- Ibandronate Oral Tablet
- Where
- South Korea
- Volunteers
- 121 people
- Sponsor
- Yeouido St. Mary's Hospital
Menopause, Type 2 Diabetes
Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis
The overall aim is to investigate the hypothesis that restoring E2 levels through MHT improves glucose and energy homeostasis and potentiates the beneficial effects of GLP-1RA in early postmenopausal women with pre- or existing…
- Trial name
- DECLARED-CT (NCT06715514)
- Testing
- GLP-1 Receptor Agonist, Menopausal Hormone Therapy
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Lia Bally
Postmenopausal Diabetes
Effects of Different Exercise Training Dose on Exercise Performance and Noninvasively Estimated Muscle Oxygen Extraction in Diabetic Postmenopausal Women
The purpose of this study is specifically to investigate (1) the exercising muscle oxygenation response in diabetic postmenopausal women; (2) the dose-response of different physical activity interventions on skeletal muscle…
- Trial name
- NCT00905203
- Testing
- exercise
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity, Sarcopenia
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes
The aim of TIMEDIAB is to demonstrate that early TRE (eTRE) combined to late (afternoon) exercise will outperform eTRE combined to morning exercise on muscle function as primary endpoint, and glucose homeostasis as secondary…
- Conditions
- Obesity, Sarcopenia, Post Menopause, Type 2 Diabetes
- Trial name
- TIMEDIAB (NCT07075133)
- Testing
- Antidiabetic diet (control), eTRE diet, Physical activity in the morning
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Bone Metabolism
Efficacy of Pioglitazone on Bone Metabolism in Postmenopausal Women With Impaired Fasting Glucose.
The purpose of this study is to evaluate the effect of pioglitazone on bone metabolism in postmenopausal women with impaired fasting glucose.
- Trial name
- NCT00708175
- Testing
- Pioglitazone
- Where
- 34 sites in United States
- Volunteers
- 156 people
- Sponsor
- Takeda
Coronary Arteriosclerosis
Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease
This study will measure and compare the levels of endothelial progenitor cells (EPCs) in the blood of people with and without risk factors for atherosclerosis (hardening of the arteries) to see if there is a relationship between…
- Trial name
- NCT00013975
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Type 2
Preventing Diabetic Osteoporosis With Exercise
The two specific aims of the study were to determine whether: 1. Greater mechanical loading of downhill exercise will increase the osteogenic index (ratio between CICP, the marker of bone formation (c-terminal propeptide of type…
- Trial name
- DIABETICBONE (NCT03930758)
- Testing
- Behavior intervention of uphill exercise, Dietary intervention of exercise before the meal, Dietary intervention of uphill exercise
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Postmenopausal Osteoporosis, Diabetes Type 2
MiDeTe - microRNA Levels Under Denosumab and Teriparatide Therapy in Postmenopausal Osteoporosis
The aim of this study is the quantitative determination of bone-specific microRNAs in the serum of postmenopausal women with osteoporosis during antiresorptive or osteoanabolic therapy.
- Trial name
- NCT03472846
- Testing
- Prolia, 60 Mg/mL Subcutaneous Solution, Teriparatide
- Where
- Austria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna