Clinical trials: Postmenopausal Symptoms, open to volunteers
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Urinary Incontinence, Postmenopausal
Effects of Multiple Intervention on Postmenopausal Women With UI
Study The purpose of this clinical trial was to investigate the effects of a multi-intervention approach, including Kegel and Tai Chi exercises, on quality of life, self-efficacy, and urinary incontinence severity in…
- Trial name
- UI Program (NCT07324668)
- Testing
- Combined Exercise Program
- Volunteers
- 117 people
- Sponsor
- Ondokuz Mayıs University
Stress Urinary Incontinence
Peri-Urethral Platelet-Rich Plasma Injections for Postmenopausal Female Stress Urinary Incontinence
his prospective interventional study will evaluate the effectiveness and safety of peri-urethral injections of platelet-rich plasma for treating stress urinary incontinence in postmenopausal women.
- Trial name
- NCT07807982
- Testing
- Autologous Platelet-Rich Plasma
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Migraine, Menopausal
Migraine Menopause Study
This study will assess whether the migraine medication eptinezumab (Vyepti) reduces migraine days in women who are in perimenopause and early menopause and who also experience night sweats and hot flashes.
- Conditions
- Migraine, Menopausal, Perimenopause
- Trial name
- NCT07916571
- Testing
- Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution
- Volunteers
- 120 people
- Sponsor
- Alberta Neurologic Centre
Obesity (BMI Equal to or >30), Postmenopausal Symptoms
Time-Restricted Eating and Personalized Energy-Restricted Diet in Obese Postmenopausal Women
This clinical study aims to compare the effects of time-restricted eating and a personalized energy-restricted diet on anthropometric measurements, body composition, biochemical parameters, blood pressure, handgrip strength…
- Conditions
- Obesity (BMI Equal to or >30), Postmenopausal Symptoms, Sleep Quality
- Trial name
- NCT07874399
- Testing
- Time-Restricted Eating, Personalized Energy-Restricted Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Psychosocial Functioning, Mindfulness
Psychosocial Effects of Mindfulness-Based Exercise in Postmenopausal Women
Menopause is a natural biological process characterized by the permanent cessation of the menstrual cycle in women. Hormonal changes associated with menopause commonly lead to mood swings, anxiety, depression, stress, and…
- Conditions
- Psychosocial Functioning, Mindfulness, Postmenopausal Symptoms
- Trial name
- NCT07424521
- Testing
- Mindfulness-Based Stress Reduction Training
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Halic University
Poor Sleep Quality, Gut Microbiome
The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) use affects gut microbiome composition, inflammation, and the body's daily temperature and blood pressure…
- Conditions
- Poor Sleep Quality, Gut Microbiome, Gut Health, Inflammation
- Trial name
- NCT07848594
- Testing
- Overnight Active Temperature Regulation: Eight Sleep Pod System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eight Sleep Inc.
Postmenopause, Overweight
Spirulina Supplementation in Postmenopausal Women
The purpose of this study is to investigate the effects of spirulina supplementation on weight gain associated with menopause, changes in metabolic parameters, sleep quality, and markers of depression in mildly overweight…
- Trial name
- NCT07718399
- Testing
- Spirulina
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Halic University
Obesity
Thermogenenic Responses to Fasting and Overfeeding in Women
This study plans to learn more about why menopause increases the risk of weight gain. During and after menopause, women are prone to increased weight gain.
- Trial name
- NCT06610162
- Testing
- Eucalaloric feeding, Acute Fasting, Acute Overfeeding
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postmenopausal Female Patients, Vasomotor Symptoms
Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females on Hormone Therapy
This study is examining whether short-term supplementation with inorganic nitrate in the form of beetroot juice can enhance vascular function in postmenopausal females taking hormone therapy compared to placebo.
- Conditions
- Postmenopausal Female Patients, Vasomotor Symptoms, Menopausal Hormone Therapy
- Trial name
- BEET-MHT (NCT07871396)
- Testing
- Moderate Intensity Exercise (MIE), High intensity exercise (HIE), Control (No exercise)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Menopausal Women, Menopausal Symptom Relief
Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy
Menopause is a natural stage in a woman's life that can be associated with symptoms such as hot flashes, night sweats, sleep problems, and vaginal dryness. Menopausal hormone therapy is commonly used to relieve these symptoms.
- Conditions
- Menopausal Women, Menopausal Symptom Relief, Hormone Therapy, Menopausal Hormone Therapy
- Trial name
- PRO-MHT (NCT07496294)
- Testing
- Dydrogesterone 10 MG Oral Tablet, Micronized progesterone 200 MG, Transdermal estradiol
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Vulvo Vaginal Atrophy (VVA)
Proof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal Women
Study Objectives: Primary: To assess the safety, tolerability, and systemic pharmacokinetics (PK) of AZU-101 Secondary: To evaluate efficacy of daily vaginal doses of AZU-101 in postmenopausal women on vaginal epithelium
- Trial name
- NCT06197568
- Testing
- Lasofoxifene Tartrate
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Azure Biotech Inc.
Bariatric Surgery, Bone Health
Bone and Muscle Health Following Sleeve Gastrectomy in Men, Premenopausal and Postmenopausal Women
Background: Bariatric surgery is gaining in popularity. While it's health benefits are undisputed, the older malabsorptive bariatric procedures (Roux-in-Y gastric bypass - RYGB and biliopancreatic diversion - BPD) are associated…
- Conditions
- Bariatric Surgery, Bone Health, Severe Obesity, Muscle Health
- Trial name
- BONUS (NCT06547515)
- Testing
- Bariatric surgery
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- CHU de Quebec-Universite Laval
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Menopause, Menopause Hot Flashes
Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women
This proof-of-concept, open-label, single-arm study is designed to evaluate the effects of daily consumption of Haelan 951, a fermented soy conventional food product, on self-reported menopausal vasomotor symptoms, sleep quality…
- Conditions
- Menopause, Menopause Hot Flashes, Menopause Related Conditions
- Trial name
- H951-MENO (NCT07751029)
- Testing
- Haelan 951
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Spectrum Clinical Research, LLC
Vasomotor Symptoms
Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).
This Phase 2a randomized, double-blind, placebo-controlled study evaluates the safety and efficacy of asimadoline (TP0052), a peripherally restricted selective kappa-opioid receptor agonist, for moderate to severe menopausal…
- Trial name
- NCT07042516
- Testing
- Asimadoline
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Tioga Pharmaceuticals
Menopause, Menopausal Hormone Therapy
A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women
This study is designed as on observational, retrospective, and prospective clinical registry aimed at collecting comprehensive real-world data on women in perimenopause, menopause, and with premature ovarian insufficiency (POI)…
- Conditions
- Menopause, Menopausal Hormone Therapy, Menopause Surgical, Menopause Related Conditions
- Trial name
- NCT07606326
- Volunteers
- 5,000 people
- Sponsor
- IRCCS San Raffaele
Overweight and Obesity
A Study to Investigate Safety, Tolerability and Pharmacokinetics of LAE103 or LAE103 in Combination With LAE102 in Healthy Overweight/Obese Participants
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of LAE103 injection in healthy overweight/obese participants or healthy postmenopausal women.
- Trial name
- NCT07230496
- Testing
- LAE103 injection, LAE102 injection in combined with LAE103 injection, Saline
- Where
- 2 sites in Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Laekna Limited
Constipation
Effect of Whole-body Vibration on Postmenopausal Constipation
This study will be conducted to investigate the effect of whole-body vibration on postmenopausal constipation
- Trial name
- NCT07196761
- Testing
- Bowel care advice, Whole-body vibration
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Arthralgia, Menopause
The MUSE Study for Menopausal Arthralgia
The investigators plan to conduct a pilot 4-arm, randomized study comprising the following interventions: muscle strengthening exercises (MSE) alone, estrogen therapy (ET) alone, and a combination of MSE and ET, compared to usual…
- Conditions
- Arthralgia, Menopause, Perimenopausal Disorder, Joint Pain
- Trial name
- MUSE (NCT06530459)
- Testing
- Menopausal hormone therapy, Exercise training, Menopausal hormone therapy + exercise training
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore