Clinical trials: Postmenopause
Metabolic Syndrome, Protection Against, Menopause
Diet, Cardiometabolic Risk (CM) and Menopause Symptoms
This research will explore the question 'What impact do the Mediterranean Diet (MedDiet) and the Heart UK Ultimate Cholesterol Lowering Plan (UCLP) Menopause have on cardiometabolic risk factors and the frequency and severity of…
- Trial name
- NCT05764473
- Testing
- The impact of MedDiet on cardiometabolic risk factors and menopause symptoms, The impact of UCLP on cardiometabolic risk factors and menopause symptoms
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
Metabolic Syndrome, Diet Modification
Diet for the Maintenance of Weight Loss and Metabolic Health in Obese Postmenopausal Women
The aim of the study will be comparing the effectiveness of two diets: moderate in fat with a high proportion of monounsaturated fatty acids (MUFAs) - the Mediterranean diet (MED) and 2) the low in fat and high in dietary fiber…
- Conditions
- Metabolic Syndrome, Diet Modification, Postmenopause
- Trial name
- WELCOME (NCT04136093)
- Testing
- the MED, the DASH, Control diet
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Overweight
Exercise and Phytoestrogens: Effect on Factors Predisposing to Cardiovascular Disease(CVD) in Postmenopausal Women
Menopause is characterized by a decrease of estrogen and progesterone levels and is associated with various changes in body composition, including an accumulation of total fat mass, a relocation of adiposity to the abdomen…
- Trial name
- NCT01048606
- Testing
- Phytoestrogens without exercise, Phytoestrogens + exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Université de Sherbrooke
Cardiovascular Diseases, Coronary Disease
Women's Estrogen/Progestin Lipid Lowering Hormone Atherosclerosis Regression Trial (WELL-HART)
To determine the effects, in postmenopausal women, of hormone replacement therapy on progression/regression of coronary heart disease, as measured by quantitative angiography.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000559
- Testing
- estrogen replacement therapy, hormone replacement therapy, estradiol
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Postmenopause, Breast Cancer
A Treatment With Fulvestrant and Exemestane in Postmenopausal Patients With Advanced Hormone Receptor-Positive (HR) + Breast Cancer
For patients receiving Faslodex 500 mg, to compare the effectiveness in terms of Time to Progression (TTP) as a function of the line of treatment (i.e. 1st vs. 2nd vs. 3rd line).
- Trial name
- ACT-FASTER: (NCT01171417)
- Where
- 92 sites in Germany
- Volunteers
- 570 people
- Sponsor
- AstraZeneca
Postmenopause
Pharmacogenetic Study of Different Hormone Therapies in Recent Menopause Women
This is cross-over, randomized clinical trial, with objective to evaluate the effects of low-dose oral hormone therapy and non-oral hormone therapy on endothelial function markers (fibrinogen, von Willebrand factor, c-reactive…
- Trial name
- NCT01432028
- Testing
- Estradiol and Progesterone, Estradiol and Drospirenone
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Denusa Wiltgen
Postmenopause, Sexual Function
On the Effect of a Hybrid Health Literacy Intervention on Sexual Function and Digital Health Literacy in Menopausal Women
This randomized controlled study will evaluate whether a hybrid health literacy education program improves sexual function and digital health literacy in postmenopausal women.
- Conditions
- Postmenopause, Sexual Function, Health Literacy, Digital Health Literacy
- Trial name
- EHHLI-MNP (NCT07839416)
- Testing
- Hybrid Health Literacy Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Postmenopausal Symptoms
Vascular Effect of CIMICIFUGA RACEMOSA
Postmenopausal women with vascular symptoms will use Cimifuga Racemosa or Placebo and the effects will be evaluated using Flow-Mediated Dilatation of the brachial artery.
- Trial name
- CRDILA (NCT03786809)
- Testing
- Cimifuga Racemosa
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Minas Gerais
Sleep Disturbance
Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints
This open-label study was designed to evaluate whether a daily dietary sleep supplement could improve sleep quality and related daytime well-being in menopausal women aged 40 to 65 with sleep complaints.
- Trial name
- NCT07839312
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Menopausal Complaints
Effect Of Transcutaneous Tibial Nerve Stimulation Technique Combined With Exercise on High Post-Void Residual Urine Volume in Post-Menopausal Women
Objective of the study is to explore effect of combining transcutaneous tibial nerve stimulation with exercise on high post-void residual urine volume in post-menopausal women.
- Trial name
- NCT07538895
- Testing
- Transcutaneous Tibial Nerve Stimulation Technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Postmenopause, Metabolism
GLYLO Supplement Pilot Trial on Glycation and Aging in Postmenopausal Women
The aim of this study is to assess the effectiveness of GLYLO, a dietary supplement, in postmenopausal women aged 45 to 65 who are overweight or obese and have elevated HbA1c levels.
- Conditions
- Postmenopause, Metabolism, Geroscience
- Trial name
- GRACE (NCT06813261)
- Testing
- GLYLO
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Buck Institute for Research on Aging
Atrophy of Vagina, Postmenopause
Sustainability of Vaginal Estrogen Therapy in Postmenopausal Women
Sustainability of vaginal ultra-low dose estrogen therapy in postmenopausal women
- Trial name
- NCT02887885
- Testing
- Gynoflor
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Postmenopause
Study Evaluating Bazedoxifene/CE in Postmenopausal Women
The purpose of this clinical trial is to study the blood levels of a drug (conjugated estrogens) in the body from one dosage form compared to another.
- Trial name
- NCT00550433
- Testing
- Bazedoxifene/Conjugated Estrogens
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Ovarian Cancer
Psychosexual Consequences of Risk-reducing Salpingo-oophorectomy
Short Rationale: Risk-reducing salpingo-oophorectomy (RRSO) is a mainstay in preventing ovarian cancer in BRCA1/2 mutation carriers, as ovarian cancer screening is ineffective in detecting ovarian cancer in an early and curable…
- Trial name
- PURSUE (NCT02372864)
- Testing
- Mindfulness based stress reduction (MBSR)
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- University Medical Center Groningen
Endometrial Neoplasms, Postmenopause
HE4 in the Diagnostic Approach of Endometrial Cancer in Patients With Postmenopausal Bleeding
This study aims to explore the sensitivity of an innovative marker, HE4, in the diagnosis approach of endometrial cancer in case of postmenopausal bleedings.
- Conditions
- Endometrial Neoplasms, Postmenopause, Uterine Hemorrhage, Cancer Biomarker
- Trial name
- METRODEC (NCT04867109)
- Testing
- Patients with Post menopausal bleeding, CA125 and HE4 assays
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Menopause
Raising Insulin Sensitivity in Post Menopause
The purpose of this study is to find out if a novel drug approved by the Food and Drug Administration [Duavee™, Pfizer, Inc] for treatment of postmenopausal symptoms (vaginal dryness and hot flashes) and prevention of…
- Trial name
- RISE (NCT02274571)
- Testing
- TSEC (Tissue-selective estrogen complexes)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Perimenopause, Postmenopause
The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial
This randomized controlled study will examine whether two different forms of structured health information-seeking education can help women in perimenopause or postmenopause use online health information more effectively.
- Conditions
- Perimenopause, Postmenopause, Cyberchondria, E-Health Literacy
- Trial name
- NCT07834216
- Testing
- Video-Based Health Information-Seeking Education, Pecha Kucha-Based Health Information-Seeking Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dyslipidemia, Menopause
Dose-response Study of Carduus Marianus in Centesimal Scale for Dyslipidemia in Climacteric Overweighed or Obese Women.
Metabolic disorders including hypercholesterolemia and hypertriglyceridemia are present in climacteric women. Carduus marianus is a homeopathic medicine that traditionally has been used for hepatic diseases.
- Conditions
- Dyslipidemia, Menopause, Obesity
- Trial name
- NCT02775448
- Testing
- Carduus marianus 6cH, Carduus marianus 12cH, Carduus marianus 30cH
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Hospital Nacional Homeopático, Mexico
Parkinson's Disease
POETRY: Study of Estrogen Replacement Therapy in Postmenopausal Women With Parkinson's Disease
The primary objectives of the POETRY study are to assess the safety and tolerability of estrogen replacement therapy (ERT) in postmenopausal women with Parkinson's disease (PD) and to assess recruitment for a study of ERT in…
- Trial name
- NCT00234676
- Testing
- Premarin ®
- Where
- 6 sites in United States
- Volunteers
- 23 people
- Sponsor
- The Parkinson Study Group