Clinical trials: Postmenopause
Pelvic Floor
Effects of Physical Training and Isoflavone Supplementation On Pelvic Floor in Women in the Postmenopausal Period
This study evaluates the effect of Physical Training and Supplementation of Isoflavone About Pelvic Floor Musculature in Women in the Postmenopausal period, and it has two groups the intervetion.
- Trial name
- NCT03167827
- Testing
- Exercise, isoflavone
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Osteoporosis, Postmenopause
The Effect of Mechanical Loading on Bone Material Strength and Microarchitecture in Postmenopausal Women
Osteoporosis is a large public health disease, characterized by low bone mass and micro architectural deterioration of bone tissue, resulting in enhanced bone fragility and consequent increase in fracture risk.
- Trial name
- NCT02339051
- Testing
- Jumping on one leg
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mattias Lorentzon
Postmenopause, Aging
Postmenopausal Women Estrogen and Progesterone Infusion
The purpose of the study is to study the effects of aging, estrogen and progesterone on the brain. Specifically, we want to look at how the hypothalamus and pituitary (two small glands in the brain) respond to estrogen.
- Trial name
- NCT00455741
- Testing
- Estradiol infusion, Progesterone infusion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Insulin Resistance Syndrome
Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause
Background: In postmenopausal females, Insulin resistance is commonly encountered in clinical setting. Hyperbaric oxygen therapy have been proposed effective in lowering blood glucose level and improving function.
- Trial name
- NCT06806345
- Testing
- Hyperbaric oxygen therapy, Hypoglycemic Drug
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Postmenopause
Effect of Two Different Isoflavone Supplement Preparations on Gene-expression in Postmenopausal Women
Alleged benefits experienced after the consumption of soy in Asian countries have been attributed to the isoflavone content of soy products.
- Trial name
- ISOII (NCT01556737)
- Testing
- High daidzein supplement, High genistein supplement
- Where
- Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Post-menopause
Beetroot Juice: a Natural Aid for Boosting the Health Benefits of Exercise in Post-menopausal Women?
Menopause and ageing bring several changes to women's health, partly due to a decline in the hormone estrogen. This reduction affects multiple systems in the body, including muscles and bones, and also influences the production…
- Trial name
- BEETBOOST (NCT07572877)
- Testing
- Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Western Norway University of Applied Sciences
Hot Flashes
Amino Acid Therapy for Hot Flashes in Postmenopausal Women
The purpose of this study is to determine the safety, tolerability, and effectiveness of the amino acid L-isoleucine in the treatment of hot flashes in postmenopausal women.
- Trial name
- NCT00081952
- Testing
- L-norleucine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Genitourinary Syndrome of Menopause
Concomitant Treatment with Topical Hyaluronic Acid and High Concentration Oxygen Therapy (Vaginal Natural Oxygenation Device - VNOD) in the Improvement of Symptoms Related to Genitourinary Syndrome of Menopause in Women with Natural and Oncological Postmenopause: Open-Label, Single-Center, Randomize
The Caress study is a single-center, open-label, randomized controlled trial (RCT) evaluating the efficacy of a combined treatment using topical hyaluronic acid and high-concentration oxygen therapy (Vaginal Natural Oxygenation…
- Trial name
- Caress (NCT06879938)
- Testing
- High-concentration vaginal oxygen therapy (Caress Flow) with topical hyaluronic acid, hyaluronic acid-based gel (Hydeal-D®)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Menopause, Perimenopause
Hop Extract Versus Soy Isoflavone Extract for Menopausal Symptoms (HOPES)
HOPES (Hops On Psychological and Estrogenic Symptoms in Menopause) is a randomized, double-blind, active-controlled nutritional intervention study in 120 peri- and postmenopausal women aged 45 to 60 years with moderate to severe…
- Conditions
- Menopause, Perimenopause, Postmenopause
- Trial name
- HOPES (NCT07904390)
- Testing
- Full Spectrum hop extract (MENODUO FullSpectrum), Soy isoflavone extract
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Menoclinica by Palacios
Bone Diseases, Cardiovascular Diseases
Postmenopausal Estrogen/Progestin Interventions (PEPI)
To assess the effects of various postmenopausal estrogen replacement therapies on selected cardiovascular risk factors, including high density lipoprotein cholesterol, systolic blood pressure, fibrinogen, and insulin and on…
- Conditions
- Bone Diseases, Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus
- Trial name
- NCT00000466
- Testing
- estrogens, conjugated, medroxyprogesterone, progesterone
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Dyspareunia
Treating Postmenopausal Dyspareunia Where it Hurts
The purpose of this study is to compare the effectiveness of two low doses of estrogen cream applied to a new location for the treatment of moderate or severe pain during sexual intercourse in postmenopausal women.
- Trial name
- NCT03240081
- Testing
- 50mcg estradiol cream, 100mcg estradiol cream
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Postmenopausal Period, Vaginal Atrophy
Vulvovaginal Atrophy Correction Using Neodymium Laser
The aim of this prospective study is characteristic of changes in the vaginal wall and vulva after treatment of neodymium laser radiation with a wavelength of 1064 nm.
- Conditions
- Postmenopausal Period, Vaginal Atrophy, Female Urogenital Diseases
- Trial name
- NCT04735549
- Testing
- Laser Treatment, Topical hormone estriol, Сlinical blood analysis
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- MeLSyTech, Ltd
Menopause, Premenopause
MyMenoPlan: Online Resource for Improving Women's Menopause Knowledge and Informed Decision-making
As part of a National Institute on Aging -funded R01, the investigators developed an evidence-based, multi-media digital resource entitled MyMenoPlan to help women learn about the menopause transition, and the symptoms and…
- Conditions
- Menopause, Premenopause, Postmenopause
- Trial name
- NCT05299983
- Testing
- MyMenoPlan, Control
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cardiovascular Diseases, Heart Diseases
Postmenopausal Progestins, MI and Stroke
To evaluate the cardiovascular effects of postmenopausal hormone replacement therapy and the suspected beneficial effects on myocardial infarction and stroke.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00005220
- Sponsor
- University of Washington
Hypercholesterolemia
Flax Lignans and Heart Health
Purpose: To demonstrate the efficacy of Beneflax™ flaxseed lignan (SDG) concentrate to lower serum cholesterol levels. Background: Flaxseed has been studied for various health benefits in humans, including prostate health…
- Trial name
- ISULignan (NCT01314586)
- Testing
- secoisolariciresinol diglucoside-containing extract of flaxseed
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Iowa State University
Amenorrhea, Postmenopause
A Study to Evaluate the Safety and Effectiveness of Asoprisnil and Estrogen Administration to Postmenopausal Women
The objective of this study is to determine the safety and effectiveness of 3 asoprisnil doses when administered to postmenopausal women with Premarin® 0.625 mg.
- Trial name
- NCT00152282
- Testing
- Asoprisnil/Premarin
- Volunteers
- 105 people
- Sponsor
- Abbott
Menopause
Relationship Between Genitourinary and Respiratory Symptoms in Postmanopause
The aim of this study is to evaluate the relationship between genitourinary system symptoms and respiratory function and respiratory muscle strength in postmenopausal women.
- Trial name
- NCT07651566
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Halic University
Postmenopause
Pharmacogenetic Study of Different Hormone Therapies in Recent Menopause Women
This is cross-over, randomized clinical trial, with objective to evaluate the effects of low-dose oral hormone therapy and non-oral hormone therapy on endothelial function markers (fibrinogen, von Willebrand factor, c-reactive…
- Trial name
- NCT01432028
- Testing
- Estradiol and Progesterone, Estradiol and Drospirenone
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Denusa Wiltgen
Postmenopause, Breast Cancer
A Treatment With Fulvestrant and Exemestane in Postmenopausal Patients With Advanced Hormone Receptor-Positive (HR) + Breast Cancer
For patients receiving Faslodex 500 mg, to compare the effectiveness in terms of Time to Progression (TTP) as a function of the line of treatment (i.e. 1st vs. 2nd vs. 3rd line).
- Trial name
- ACT-FASTER: (NCT01171417)
- Where
- 92 sites in Germany
- Volunteers
- 570 people
- Sponsor
- AstraZeneca
Healthy Female Participants, Postmenopause
A Study to Assess the Bioavailability and Adhesion of Estradiol/Levonorgestrel TDS in Healthy Post-Menopausal Female Participants
The purpose of this study is to compare the bioequivalence and adhesion performance of a test estradiol/levonorgestrel transdermal delivery system (TDS) with the reference product, Climara Pro® (estradiol/levonorgestrel…
- Trial name
- NCT07851649
- Testing
- Test Estradiol/Levonorgestrel Transdermal Delivery System, Climara Pro® (Estradiol/Levonorgestrel Transdermal System)
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.