Clinical trials: Postmenopause
Urinary Incontinence , Stress
Pelvic Floor Muscle Training vs. Pilates Exercises for Urinary Incontinence
Urinary incontinence (UI) affects approximately 40% of postmenopausal women and is therefore considered a public health problem.
- Trial name
- NCT07212478
- Testing
- PFMT, Pilates exercises
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Estadual do Norte do Parana
Postmenopause Women
Effect of 12-week FW Programme on Sex Hormone Levels and Risk Factors for MS in Postmenopausal Women
Postmenopausal women were separated into two groups: one participating in a 12-week fitness walking programe as the fitness walking group, and the other maintaining their regular lifestyle as the control group.
- Trial name
- NCT06454032
- Testing
- Fitness walking, Maintained lifestyle
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Postmenopausal Symptoms, Hot Flashes
WHAT (Women, Hot-flashes, Activity, Trial) - Physical Activity for Treatment of Hot Flushes Among Postmenopausal Women
More than 60 % of women experience hot-flashes during postmenopausal and 20 % have serious symptoms. Use of combined estrogen/progesterone therapy reduces hot-flashes effectively.
- Trial name
- WHAT (NCT01282320)
- Testing
- Physical activity intervention program
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Aging
Effect of Estrogen & Stress for Postmenopausal Women
The study tests the hypothesis that estradiol administration exacerbates the effects of the stress hormone cortisol on cognition and mood for postmenopausal women.
- Trial name
- NCT00220454
- Testing
- Climara, Hydrocortone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Post-menopausal Period
Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%
This is a Phase I, open-label, parallel trial to evaluate Pharmacokinetics, Pharmacodynamics and Safety of Testosterone gel 1% for topic usage in post-menopausal women, for 28 days
- Trial name
- NCT02667561
- Testing
- Testosterone gel 1% 2.2 mg, Testosterone gel 1% 4.4 mg, Testosterone gel 1% 8.8 mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Female Sexual Dysfunction, Postmenopausal Symptoms
Sexual Effects of Transdermal or Vaginal Testosterone
The aim of the study is to elucidate the role of testosterone treatment in postmenopausal women's sexual function and their therapeutic safety.
- Conditions
- Female Sexual Dysfunction, Postmenopausal Symptoms, Testosterone Deficiency, Testosterone Adverse Reaction
- Trial name
- NCT06794346
- Testing
- Transdermal testosterone, Vaginal testosterone gel
- Where
- Brazil
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Metabolic Syndrome, Protection Against, Menopause
Diet, Cardiometabolic Risk (CM) and Menopause Symptoms
This research will explore the question 'What impact do the Mediterranean Diet (MedDiet) and the Heart UK Ultimate Cholesterol Lowering Plan (UCLP) Menopause have on cardiometabolic risk factors and the frequency and severity of…
- Trial name
- NCT05764473
- Testing
- The impact of MedDiet on cardiometabolic risk factors and menopause symptoms, The impact of UCLP on cardiometabolic risk factors and menopause symptoms
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
Postmenopause, Energy Expenditure
Resting Energy Expenditure in Postmenopausal Women
Obesity and its associated comorbidities are rising at an alarming rate, particularly among postmenopausal women. Menopause, characterized by a decline in estradiol and progesterone levels, is often accompanied by weight gain.
- Conditions
- Postmenopause, Energy Expenditure, Hormone Replacement Therapy
- Trial name
- MenoBOLISM (NCT06905886)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postmenopause, Hot Flashes
Effects of Black Cohosh on Menopausal Hot Flashes
This study will assess whether treatment with black cohosh is effective in reducing the frequency and intensity of menopausal hot flashes.
- Conditions
- Postmenopause, Hot Flashes, Osteoporosis, Postmenopausal
- Trial name
- NCT00010712
- Testing
- Black Cohosh
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Postmenopausal Period, Postmenopausal Women
AI-Assisted Relaxation and Breathing Training in Postmenopausal Women
This study aims to evaluate the effectiveness of relaxation and breathing training delivered by a physiotherapist and by an artificial intelligence-assisted system in postmenopausal women with non-specific chronic musculoskeletal…
- Trial name
- NCT07302750
- Testing
- Physiotherapist-Guided Relaxation and Breathing Training, Artificial Intelligence-Assisted Relaxation and Breathing Training, Control Group - No Structured Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Menopause Related Conditions
Quercetin for Cardio-Skeletal Muscle Health and Estrogen Deficiency
Double blind randomized controlled parallel pilot trial of Quercetin vs placebo oral administration in 24 postmenopausal women. The study team will conduct a feasibility pilot in preparation for a larger efficacy trial that will…
- Trial name
- QUICKENED (NCT04258410)
- Testing
- Quercetin
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer
A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
The purpose of this study is to learn about the effects of the study medicine PF-07220060 plus letrozole, compared with the effects of taking letrozole alone without PF-07220060 for treatment of breast cancer.
- Trial name
- NCT06465368
- Testing
- PF-07220060, letrozole
- Where
- 51 sites in United States, Australia and 11 more
- Volunteers
- 121 people
- Sponsor
- Pfizer
Female Urogenital Diseases, Urinary Incontinence
Clinical Trial of "Magic Gyno" Laser Device
The aim of this prospective study is investigation of efficiency and safety of medical device "Magic Gyno" in accordance with the stated purpose.
- Conditions
- Female Urogenital Diseases, Urinary Incontinence, Prolapse Genital, Menopausal Syndrome
- Trial name
- NCT05463081
- Testing
- Laser treatment, Blood test, Clinical urine test
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- MeLSyTech, Ltd
Aesthetic, Menopause
Post-Menopause Skin Rejuvenation Study
The post-menopausal state is marked by a sharp decline in estrogen, leading to significant structural and functional changes in the skin, including collagen loss, dryness, thinning, and reduced elasticity.
- Conditions
- Aesthetic, Menopause, Post-menopause, Injectables
- Trial name
- NCT07205744
- Testing
- Restylane SkinBoosters Vital, Sculptra Aesthetic
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Insomniac Postmenopausal Women
Effect of Estrogen Therapy on Objective Sleep Quality in Postmenopausal Women
1. Sex hormone including estrogen have synergistic effect to serotonin activity and decrease activity of monoamine oxidase activity so the norepinephrine is not be metabolized, these substance are important to regulate hemostasis…
- Trial name
- NCT01501422
- Testing
- Estrogen patch
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Osteoporosis
Bone Estrogen Strength Training
We started the Bone, Estrogen, Strength Training (BEST) study in the fall of 1995 at the University of Arizona, Tucson, Arizona. The BEST study is the largest of its kind.
- Trial name
- NCT00000399
- Testing
- Hormone replacement therapy, Strength training
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Postmenopause, Overweight
Spirulina Supplementation in Postmenopausal Women
The purpose of this study is to investigate the effects of spirulina supplementation on weight gain associated with menopause, changes in metabolic parameters, sleep quality, and markers of depression in mildly overweight…
- Trial name
- NCT07718399
- Testing
- Spirulina
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Halic University
Postmenopausal Period, Fatigue
The Effect of Progressive Relaxation Exercises on Sleep Quality and Fatigue in Postmenopausal Period
The population of the study will be postmenopausal women who applied to the KETEM unit of a hospital in western Turkey for examination. This study is a two-group randomized controlled study.
- Conditions
- Postmenopausal Period, Fatigue, Sleep Quality
- Trial name
- NCT05483413
- Testing
- progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Bone Diseases, Cardiovascular Diseases
CVD Risk and Health in Postmenopausal Phytoestrogen Users
To determine the acceptability and benefits of use of a dietary supplement of the phytoestrogen, genistein, versus placebo on heart disease risk factors, bone density, and psychosocial outcomes in postmenopausal women.
- Conditions
- Bone Diseases, Cardiovascular Diseases, Coronary Disease, Depression
- Trial name
- NCT00000613
- Testing
- dietary supplements, genistein, diet, soy proteins
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Diabetes Mellitus
Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and Menopause
To determine if the increase in low density lipoprotein (LDL) cholesterol at the time of menopause could be ameliorated or prevented by an intensive dietary intervention.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Heart Diseases, Hypercholesterolemia
- Trial name
- NCT00000532
- Testing
- diet, fat-restricted
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)