Clinical trials: Postmenopause
Menopause
The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Non-Hysterectomized Postmenopausal Women
To determine whether treatment with ESTRATEST® Tablets is superior to treatment with esterified estrogens tablets
- Trial name
- NCT00141544
- Testing
- esterified estrogens 1.25 mg and methyltestosterone 2.5 mg, Esterified estrogens 1.25 mg
- Where
- 78 sites in United States
- Volunteers
- 28 people
- Sponsor
- Solvay Pharmaceuticals
Sleep Disturbances
Bonafide Sleep Supplement for Menopausal Women With Impaired Sleep
This open-label study evaluated whether a daily dietary sleep supplement could improve sleep and related daytime functioning in menopausal women aged 40 to 65 with impaired sleep.
- Trial name
- NCT07839299
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
HIV Infections
Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women
The purpose of this study is to find out if the anti-HIV drugs nelfinavir (NFV), lopinavir/ritonavir (LPV/r), and efavirenz (EFV) change the amount of estrogen in the blood when taken along with hormone replacement therapy (HRT)…
- Trial name
- NCT00044837
- Testing
- Medroxyprogesterone acetate, Estradiol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-3
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01045811
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Postmenopause
Study Evaluating Potential Drug Interaction Of Bazedoxifene & Premarin In Healthy Postmenopausal Women
Bazedoxifene (BZA) 20 mg tablet is an investigational medication (not approved by FDA) which is being studied for possible prevention and treatment of postmenopausal osteoporosis.
- Trial name
- NCT00706225
- Testing
- Bazedoxifene and conjugated estrogens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Metabolic Syndrome, Postmenopausal Symptoms
Circadian Rhythms in Postmenopausal Women
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms…
- Trial name
- NCT04893226
- Testing
- Time-Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Perimenopause, Postmenopause
The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial
This randomized controlled study will examine whether two different forms of structured health information-seeking education can help women in perimenopause or postmenopause use online health information more effectively.
- Conditions
- Perimenopause, Postmenopause, Cyberchondria, E-Health Literacy
- Trial name
- NCT07834216
- Testing
- Video-Based Health Information-Seeking Education, Pecha Kucha-Based Health Information-Seeking Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postmenopause, Menopausal Complaints
The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women
This trial investigates whether supervised training in combination with hormonal substitution therapy has an impact on body composition, cardiovascular risk, risk for dementia, osteoporosis and insulin sensitivity in…
- Trial name
- OPERATE (NCT05831709)
- Testing
- Exercise program, Hormonal substitution therapy per SOC
- Where
- Belgium
- Volunteers
- 390 people
- Sponsor
- University Hospital, Ghent
Osteoporosis
Alendronate and/or Parathyroid Hormone for Osteoporosis
This study looks at the effects of two medications, alendronate and parathyroid hormone, on bone mass and on bone formation and bone breakdown in women with osteoporosis.
- Trial name
- NCT00000400
- Testing
- Human parathyroid hormone [hPTH-(1-34)], alendronate
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Massachusetts General Hospital
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Glucose Monitoring, Continuous, Whole Body Protein Metabolism
Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women
The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormonal changes can adversely affect protein metabolism and muscle…
- Conditions
- Glucose Monitoring, Continuous, Whole Body Protein Metabolism, Peri-menopausal Women, Post-menopause
- Trial name
- NCT07402382
- Testing
- Amylopectin-chromium blend, Concentrated Amylopectin-chromium blend
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutrition 21, Inc.
Circadian Rhythm, Postoperative Sleep Disturbance
Effect of Esketamine on Postoperative Sleep in Postmenopausal Women
The prevalence of sleep disturbance among postmenopausal women has been reported to reach 51.6%. Epidemiological studies consistently show that the incidence of sleep disorders increases with age and menopausal transition.
- Trial name
- NCT07315074
- Testing
- Esketamine, Normal Saline
- Where
- 2 sites in China
- Volunteers
- 164 people
- Sponsor
- Zhuan Zhang
Postmenopause
Tolerability & Safety of Premarin Vaginal Cream in Indian Postmenopausal Women
This post-marketing study will provide local safety and tolerance data on the use of Premarin® vaginal cream.
- Trial name
- NCT00484107
- Testing
- Conjugated Estrogen Cream (Premarin®)
- Volunteers
- 200 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Postmenopause
To Evaluate the Impact of Smoking on PK After Single-dose Oral Administration of GS1-144 Tablets .
A Drug-Drug Interaction Study to Evaluate the Effect of Smoking (CYP1A2 Inducer) on the Pharmacokinetics Following a Single Oral Dose of GS1-144 Tablets in Chinese Healthy Postmenopausal Female Trial Participants
- Trial name
- NCT07534176
- Testing
- GS1-144 tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Heart Failure, Congestive, Cardiovascular Diseases
Effects of Exercise Training on Diastolic Heart Function in Postmenopausal Women
This study is a prospective follow-up study to the Dose-Response to Exercise in Women (DREW) study. In DREW, 450 overweight, sedentary postmenopausal women were randomly assigned to either a non-exercise control group or to 1 of…
- Trial name
- NCT00125476
- Testing
- Exercise
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Atherosclerosis, Chlamydia Infections
Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
Hardening of the arteries (atherosclerosis) and heart disease are much more common in men than in women. However, as women grow older, especially after menopause the incidence of atherosclerosis and heart disease increases.
- Conditions
- Atherosclerosis, Chlamydia Infections, Cytomegalovirus Infections, Pneumonia, Bacterial
- Trial name
- NCT00001890
- Testing
- Estrogen therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Menopause
Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndromes and Measurements of the Urinary Vitamin B3 and Estradiol Levels in Pre-, Peri- and Post-menopause
The purpose of this study is to determine whether a short supplementation (7days) with BASIS™ increases the natural production of estradiol, measured in urinary waste.
- Trial name
- NCT04841499
- Testing
- BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Osteopenia
Study to Investigate if Adding Lactulose to Vitamin D and Calcium Has an Effect on the Preservation of Bone in Postmenopausal Women
This is a randomized, double-blind, multicentre, parallel pilot clinical trial to study the efficacy of a treatment of lactulose 15 ml + vitamin D 400 U + calcium 0.5 g compared to lactulose placebo 15 ml + vitamin D 400 U +…
- Trial name
- NCT00160264
- Testing
- Lactulose, Vitamin D, Calcium
- Where
- 3 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Solvay Pharmaceuticals
Post Menopausal
Effects of Progressive Resistance Training Vasomotor Symptoms in Post Menopausal Women
The study will be a randomized clinical trial and will be conducted in Civil Hospital and Kalsoom Hospital Samundry. This study will be completed in time duration of 10 months after the approval of synopsis.
- Trial name
- NCT06166264
- Testing
- Progressive resistance training, Control group
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postmenopause, Sexual Function
On the Effect of a Hybrid Health Literacy Intervention on Sexual Function and Digital Health Literacy in Menopausal Women
This randomized controlled study will evaluate whether a hybrid health literacy education program improves sexual function and digital health literacy in postmenopausal women.
- Conditions
- Postmenopause, Sexual Function, Health Literacy, Digital Health Literacy
- Trial name
- EHHLI-MNP (NCT07839416)
- Testing
- Hybrid Health Literacy Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University